The p38 mitogen activated protein kinase inhibitor losmapimod in chronic obstructive pulmonary disease patients with systemic inflammation, stratified by fibrinogen: A randomised double-blind placebo-controlled trial

Plasma Fibrinogen Qualification as a Drug Development Tool in Chronic Obstructive Pulmonary Disease. Perspective of the Chronic Obstructive Pulmonary Disease Biomarker Qualification Consortium

(2016) Bruce E. Miller et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Therapeutic Potential of p38 MAP Kinase Inhibition in the Management of Cardiovascular Disease

(2014) Marie Fisk et al.   American Journal of Cardiovascular Drugs

Losmapimod, a novel p38 mitogen-activated protein kinase inhibitor, in non-ST-segment elevation myocardial infarction: a randomised phase 2 trial

(2014) L Kristin Newby et al.   LANCET

Intensification of Statin Therapy Results in a Rapid Reduction in Atherosclerotic Inflammation

(2013) Ahmed Tawakol et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

P38 inhibition in COPD; cautious optimism

(2013) Dave Singh   THORAX

Efficacy and safety of the p38 MAPK inhibitor losmapimod for patients with chronic obstructive pulmonary disease: a randomised, double-blind, placebo-controlled trial

(2013) Henrik Watz et al.   Lancet Respiratory Medicine

Anti-Tumor Necrosis Factor-α Therapy Reduces Aortic Inflammation and Stiffness in Patients With Rheumatoid Arthritis

(2012) Kaisa M. Mäki-Petäjä et al.   CIRCULATION

Blood fibrinogen as a biomarker of chronic obstructive pulmonary disease: Table 1

(2012) Annelyse Duvoix et al.   THORAX

Clinical and Radiographic Predictors of GOLD–Unclassified Smokers in the COPDGene Study

(2011) Emily S. Wan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Fibrinogen and cardiovascular disease: Genetics and biomarkers

(2011) Dimitris Tousoulis et al.   BLOOD REVIEWS

Inhibition of p38 Mitogen-Activated Protein Kinase Improves Nitric Oxide–Mediated Vasodilatation and Reduces Inflammation in Hypercholesterolemia

(2011) Joseph Cheriyan et al.   CIRCULATION

An Oral Inhibitor of p38 MAP Kinase Reduces Plasma Fibrinogen in Patients With Chronic Obstructive Pulmonary Disease

(2011) David A. Lomas et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Aortic calcification, arterial stiffness and bone mineral density in patients with COPD

(2011) Charlotte E. Bolton et al.   Artery Research

Increased Risk of Myocardial Infarction and Stroke Following Exacerbation of COPD

(2009) Gavin C. Donaldson et al.   CHEST

Systemic manifestations and comorbidities of COPD

(2009) P. J. Barnes et al.   EUROPEAN RESPIRATORY JOURNAL

Determinants of Systemic Vascular Function in Patients with Stable Chronic Obstructive Pulmonary Disease

(2008) Philipp Eickhoff et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE