TDP-43 causes neurotoxicity and cytoskeletal dysfunction in primary cortical neurons
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Title
TDP-43 causes neurotoxicity and cytoskeletal dysfunction in primary cortical neurons
Authors
Keywords
Neurons, Axons, Motor neurons, Cytoskeleton, Immunostaining, Toxicity, Apoptosis, Axonal transport
Journal
PLoS One
Volume 13, Issue 5, Pages e0196528
Publisher
Public Library of Science (PLoS)
Online
2018-05-23
DOI
10.1371/journal.pone.0196528
References
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Note: Only part of the references are listed.- Futsch/MAP1B mRNA Is a Translational Target of TDP-43 and Is Neuroprotective in a Drosophila Model of Amyotrophic Lateral Sclerosis
- (2014) A. N. Coyne et al. JOURNAL OF NEUROSCIENCE
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- (2014) Sami J Barmada et al. Nature Chemical Biology
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- (2014) Nael H. Alami et al. NEURON
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- (2014) Bradley N. Smith et al. NEURON
- ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43
- (2013) E. S. Arnold et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2012) Claudia Fallini et al. HUMAN MOLECULAR GENETICS
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- (2011) Fabienne C. Fiesel et al. FEBS Journal
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- (2011) James R Tollervey et al. NATURE NEUROSCIENCE
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- (2010) S. J. Barmada et al. JOURNAL OF NEUROSCIENCE
- TDP-43-Based Animal Models of Neurodegeneration: New Insights into ALS Pathology and Pathophysiology
- (2010) Iga Wegorzewska et al. Neurodegenerative Diseases
- The multiple roles of TDP-43 in pre-mRNA processing and gene expression regulation
- (2010) Emanuele Buratti et al. RNA Biology
- Rethinking ALS: The FUS about TDP-43
- (2009) Clotilde Lagier-Tourenne et al. CELL
- Expression of TDP-43 C-terminal Fragmentsin VitroRecapitulates Pathological Features of TDP-43 Proteinopathies
- (2009) Lionel M. Igaz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration
- (2009) I. Wegorzewska et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6
- (2009) C. Vance et al. SCIENCE
- TDP-43A315T mutation in familial motor neuron disease
- (2008) Michael A. Gitcho et al. ANNALS OF NEUROLOGY
- TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis
- (2008) Vivianna M Van Deerlin et al. LANCET NEUROLOGY
- TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis
- (2008) Edor Kabashi et al. NATURE GENETICS
- TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
- (2008) J. Sreedharan et al. SCIENCE
- TDP-43: an emerging new player in neurodegenerative diseases
- (2008) I-Fan Wang et al. TRENDS IN MOLECULAR MEDICINE
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