Reprogramming of the estrogen responsive transcriptome contributes to tamoxifen-dependent protection against tumorigenesis in the p53 null mammary epithelial cells

Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53-deficient mammary cancers

(2016) Adam D. Pfefferle et al.   Disease Models & Mechanisms

Proven value of translational research with appropriate animal models to advance breast cancer treatment and save lives: the tamoxifen tale

(2015) V. Craig Jordan   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Reprogramming of the ERR  and ER  Target Gene Landscape Triggers Tamoxifen Resistance in Breast Cancer

(2015) V. Thewes et al.   CANCER RESEARCH

Steroid Hormones, Steroid Receptors, and Breast Cancer Stem Cells

(2015) Jessica Finlay-Schultz et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Endocrine hormones and local signals during the development of the mouse mammary gland

(2015) Cathrin Brisken et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Tamoxifen as the first targeted long-term adjuvant therapy for breast cancer

(2014) V Craig Jordan   ENDOCRINE-RELATED CANCER

p53 in breast cancer subtypes and new insights into response to chemotherapy

(2013) Philippe Bertheau et al.   BREAST

Hallmarks of Aromatase Inhibitor Drug Resistance Revealed by Epigenetic Profiling in Breast Cancer

(2013) M. P. H. M. Jansen et al.   CANCER RESEARCH

Anastrozole for prevention of breast cancer in high-risk postmenopausal women (IBIS-II): an international, double-blind, randomised placebo-controlled trial

(2013) Jack Cuzick et al.   LANCET

Research Resource: Progesterone Receptor Targetome Underlying Mammary Gland Branching Morphogenesis

(2013) Ashlee R. Lain et al.   MOLECULAR ENDOCRINOLOGY

Genome-wide reprogramming of the chromatin landscape underlies endocrine therapy resistance in breast cancer

(2013) L. Magnani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein tyrosine phosphatases - from housekeeping enzymes to master regulators of signal transduction

(2012) Nicholas K. Tonks   FEBS Journal

Luteinizing Hormone/Human Chorionic Gonadotropin-Mediated Activation of mTORC1 Signaling Is Required for Androgen Synthesis by Theca-Interstitial Cells

(2012) Murugesan Palaniappan et al.   MOLECULAR ENDOCRINOLOGY

Differential oestrogen receptor binding is associated with clinical outcome in breast cancer

(2012) Caryn S. Ross-Innes et al.   NATURE

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

p53 mutations in cancer

(2012) Patricia A. J. Muller et al.   NATURE CELL BIOLOGY

Activation of Multiple Proto-oncogenic Tyrosine Kinases in Breast Cancer via Loss of the PTPN12 Phosphatase

(2011) Tingting Sun et al.   CELL

Exemestane for Breast-Cancer Prevention in Postmenopausal Women

(2011) Paul E. Goss et al.   NEW ENGLAND JOURNAL OF MEDICINE

Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cells

(2011) J. I. Herschkowitz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo

(2011) Kristen L. Meerbrey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antiestrogens and Their Therapeutic Applications in Breast Cancer and Other Diseases

(2010) Simak Ali et al.   Annual Review of Medicine

Tyrosine dephosphorylation is required for Bak activation in apoptosis

(2010) Joanna L Fox et al.   EMBO JOURNAL

Control of mammary stem cell function by steroid hormone signalling

(2010) Marie-Liesse Asselin-Labat et al.   NATURE

Progesterone induces adult mammary stem cell expansion

(2010) Purna A. Joshi et al.   NATURE

FOXA1 is a key determinant of estrogen receptor function and endocrine response

(2010) Antoni Hurtado et al.   NATURE GENETICS

Hormone Action in the Mammary Gland

(2010) C. Brisken et al.   Cold Spring Harbor Perspectives in Biology

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

(2009) Balazs Györffy et al.   BREAST CANCER RESEARCH AND TREATMENT

An oestrogen-receptor-α-bound human chromatin interactome

(2009) Melissa J. Fullwood et al.   NATURE

Predicting prognosis using molecular profiling in estrogen receptor-positive breast cancer treated with tamoxifen

(2008) Sherene Loi et al.   BMC GENOMICS