Biomolecular study of human thymidylate synthase conformer-selective inhibitors: New chemotherapeutic approach

Crystal structure of the active form of native human thymidylate synthase in the absence of bound substrates

(2017) P. Deschamps et al.   Acta Crystallographica Section F-Structural Biology Communications

Virtual screening reveals allosteric inhibitors of the Toxoplasma gondii thymidylate synthase–dihydrofolate reductase

(2014) Hitesh Sharma et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Evolution of Metamorphism in Thymidylate Synthases Within the Primate Lineages

(2011) BeiBei Luo et al.   JOURNAL OF MOLECULAR EVOLUTION

TS and ERCC-1 mRNA expressions and clinical outcome in patients with metastatic colon cancer in CONFIRM-1 and -2 clinical trials

(2011) P P Grimminger et al.   PHARMACOGENOMICS JOURNAL

Protein-protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase

(2011) D. Cardinale et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel Approaches for Targeting Thymidylate Synthase To Overcome the Resistance and Toxicity of Anticancer Drugs

(2010) Divita Garg et al.   JOURNAL OF MEDICINAL CHEMISTRY

Human thymidylate synthase with loop 181-197 stabilized in an inactive conformation: Ligand interactions, phosphorylation, and inhibition profiles

(2010) BeiBei Luo et al.   PROTEIN SCIENCE

Variants of human thymidylate synthase with loop 181-197 stabilized in the inactive conformation

(2009) Leslie L. Lovelace et al.   PROTEIN SCIENCE

The R163K Mutant of Human Thymidylate Synthase Is Stabilized in an Active Conformation: Structural Asymmetry and Reactivity of Cysteine 195†‡

(2008) Lydia M. Gibson et al.   BIOCHEMISTRY