DEC205-DC targeted DNA vaccine against CX3CR1 protects against atherogenesis in mice

Role of the CX3C chemokine receptor CX3CR1 in the pathogenesis of atherosclerosis after aortic transplantation

(2017) Zuzanna Rowinska et al.   PLoS One

A novel CX3CR1 antagonist eluting stent reduces stenosis by targeting inflammation

(2015) Mohammed T. Ali et al.   BIOMATERIALS

Macrophage subsets in atherosclerosis

(2014) Giulia Chinetti-Gbaguidi et al.   Nature Reviews Cardiology

Chemokines and atherosclerosis: focus on the CX3CL1/CX3CR1 pathway

(2013) Stavros Apostolakis et al.   ACTA PHARMACOLOGICA SINICA

Pharmacological Inhibition of the Chemokine Receptor, CX3CR1, Reduces Atherosclerosis in Mice

(2013) Lucie Poupel et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

1,25(OH)2 vitamin D suppresses macrophage migration and reverses atherogenic cholesterol metabolism in type 2 diabetic patients

(2013) Amy E. Riek et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Role of CX3CR1 Receptor in Monocyte/Macrophage Driven Neovascularization

(2013) Arun H. S. Kumar et al.   PLoS One

Fractalkine: A Survivor's Guide

(2012) Gemma E. White et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Distribution of macrophage polarization markers in human atherosclerosis

(2012) J. Lauran Stöger et al.   ATHEROSCLEROSIS

DNA vaccine encoding CD40 targeted to dendritic cells in situ prevents the development of Heymann nephritis in rats

(2012) Ya Wang et al.   KIDNEY INTERNATIONAL

Safety and Immunogenicity of an HIV-1 Gag DNA Vaccine with or without IL-12 and/or IL-15 Plasmid Cytokine Adjuvant in Healthy, HIV-1 Uninfected Adults

(2012) Spyros A. Kalams et al.   PLoS One

Fractalkine Is Expressed in Early and Advanced Atherosclerotic Lesions and Supports Monocyte Recruitment via CX3CR1

(2012) Moritz Stolla et al.   PLoS One

Fractalkine – a local inflammatory marker aggravating platelet activation at the vulnerable plaque

(2012) Ulrike Flierl et al.   THROMBOSIS AND HAEMOSTASIS

Design of immunogenic and effective multi-epitope DNA vaccines for melanoma

(2011) Hyun-Il Cho et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

An experimental live chimeric porcine circovirus 1-2a vaccine decreases porcine circovirus 2b viremia when administered intramuscularly or orally in a porcine circovirus 2b and porcine reproductive and respiratory syndrome virus dual-challenge model

(2011) Tanja Opriessnig et al.   MICROBIOLOGY AND IMMUNOLOGY

DNA-based vaccines for multiple sclerosis: Current status and future directions

(2010) Nicolas Fissolo et al.   CLINICAL IMMUNOLOGY

Fractalkine/CX3CR1: why a single chemokine-receptor duo bears a major and unique therapeutic potential

(2010) Jan G D'Haese et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Dendritic cell targeted HIV gag protein vaccine provides help to a DNA vaccine including mobilization of protective CD8+ T cells

(2010) G. Nchinda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aspirin Inhibits Fractalkine Expression in Atherosclerotic Plaques and Reduces Atherosclerosis in ApoE Gene Knockout Mice

(2009) Hong Liu et al.   CARDIOVASCULAR DRUGS AND THERAPY

Fractalkine has anti-apoptotic and proliferative effects on human vascular smooth muscle cells via epidermal growth factor receptor signalling

(2009) Gemma E. White et al.   CARDIOVASCULAR RESEARCH

DNA vaccine therapy for chronic hepatitis C virus (HCV) infection: immune control of a moving target

(2009) Matti Sällberg et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Therapeutic HPV DNA vaccines

(2009) Archana Monie et al.   Expert Review of Vaccines

Bone marrow-derived CX3CR1 progenitors contribute to neointimal smooth muscle cells via fractalkine CX3CR1 interaction

(2009) Arun H. S. Kumar et al.   FASEB JOURNAL

CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival

(2008) L. Landsman et al.   BLOOD

Vaccination against CD99 inhibits atherogenesis in low-density lipoprotein receptor-deficient mice

(2008) E. J.A. van Wanrooij et al.   CARDIOVASCULAR RESEARCH

Combined Inhibition of CCL2, CX3CR1, and CCR5 Abrogates Ly6C hi and Ly6C lo Monocytosis and Almost Abolishes Atherosclerosis in Hypercholesterolemic Mice

(2008) Christophe Combadière et al.   CIRCULATION

The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells

(2008) Godwin Nchinda et al.   JOURNAL OF CLINICAL INVESTIGATION

Immunogenicity of CIGB-230, a therapeutic DNA vaccine preparation, in HCV-chronically infected individuals in a Phase I clinical trial

(2008) L. Alvarez-Lajonchere et al.   JOURNAL OF VIRAL HEPATITIS

Chemokines and Their Receptors: Drug Targets in Immunity and Inflammation

(2007) Antonella Viola et al.   Annual Review of Pharmacology and Toxicology

Fractalkine Deficiency Markedly Reduces Macrophage Accumulation and Atherosclerotic Lesion Formation in CCR2 −/− Mice

(2007) Noah Saederup et al.   CIRCULATION