Article
Biochemistry & Molecular Biology
Ruida Liu, Yanhui Shen, Minxuan Wang, Ruihua Liu, Ziqian Cui, Pengzhen Li, Qidi Wu, Qian Shen, Jing Chen, Siping Zhang, Shaodong Liu, Huijuan Ma, Chaoyou Pang, Changwei Ge
Summary: In this study, the upregulation of GhMYB102 gene during early stages of drought stress in upland cotton was identified through analysis of drought transcriptomic data. GhMYB102, which encodes a conserved MYB transcription factor, is closely related to AtMYB102 and is mainly expressed in roots. Silencing of GhMYB102 resulted in decreased drought resistance in plants. Furthermore, GhMYB102 was found to directly bind promoter regions of GhNCED1 and GhZAT10 and regulate their expression, suggesting its positive role in drought tolerance by participating in ABA biosynthesis or regulating the expression of drought-responsive genes.
Article
Plant Sciences
Vinod Kumar, Deepika Singh, Adity Majee, Shikha Singh, Roohi, Mehar Hasan Asif, Aniruddha P. Sane, Vidhu A. Sane
Summary: This study utilized comparative differential transcriptomic analysis to identify genes predominantly expressed during root growth in tomato, revealing common expression of around 15,000 genes and root-specific expression of approximately 3000 genes of various classes. Root-specific expression was observed for numerous transcription factors, kinases, phosphatases, and hormone pathways related to root growth.
PHYSIOLOGY AND MOLECULAR BIOLOGY OF PLANTS
(2021)
Article
Forestry
Wuqi Wei, Jinzhi He, Yiwei Luo, Zhen Yang, Xiaoyu Xia, Yuanxiang Han, Ningjia He
Summary: This study identified 15 TCP transcription factors in the mulberry genome, and found that 5 of these genes are correlated with root development and may increase mulberry tolerance to drought.
Article
Plant Sciences
Jingwei Zhang, Dazhuang Huang, Xiaojie Zhao, Man Zhang, Qian Wang, Xueyan Hou, Dongliu Di, Beibei Su, Shaokun Wang, Pai Sun
Summary: This study isolated two WRKY genes from Iris germanica and found that they play an important role in the response to drought stress. Furthermore, through the study of transgenic Arabidopsis, it was discovered that IgWRKY50 and IgWRKY32 can improve the drought tolerance of plants.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Shuchao Dong, Jiayi Ling, Liuxia Song, Liping Zhao, Yinlei Wang, Tongmin Zhao
Summary: Drought has a significant impact on tomatoes, leading to tissue dehydration and decreased yield. The key genes involved in dehydration response and tolerance in tomatoes are still not well understood. Dehydration decreases the relative water content of tomato leaves and promotes the content of malondialdehyde and ion leakage. Dehydration also triggers oxidative stress and enhances the activity of antioxidant enzymes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Agronomy
Haiju Zhao, Changhai Wang, Haiyan Lan
Summary: The bHLH transcription factor CgbHLH001 from Chenopodium glaucum was found to confer drought tolerance in maize by accumulating soluble sugar and proline contents, as well as increasing the activities of antioxidant enzymes. These findings suggest that CgbHLH001 has the potential for improving drought resistance in maize breeding.
MOLECULAR BREEDING
(2021)
Article
Plant Sciences
Joo-Seok Park, Yoram Choi, Min-Gyun Jeong, Yeong-Il Jeong, Ji-Hyun Han, Hong-Kyu Choi
Summary: This study conducted a transcriptome analysis of soybean callus to identify key genes and pathways involved in callus formation. The results showed that genes associated with hormones, cell wall modification, and cell cycle underwent transcriptional reprogramming throughout callus formation. Furthermore, it was discovered that hormones such as auxin, cytokinin, and brassinosteroid activated genes involved in root and shoot meristem development during callus formation. Overall, this study provides significant insights into the molecular mechanisms governing callus formation in soybean.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Plant Sciences
Hossein Kazemi, Atefeh Sabouri, Ali Aalami, Amin Abedi
Summary: A comprehensive meta-analysis on sorghum using RNA-seq data identified differentially expressed genes and co-expression modules associated with responses to drought and salinity stresses, providing novel insights into the molecular mechanisms of abiotic tolerance in sorghum.
JOURNAL OF PLANT GROWTH REGULATION
(2023)
Review
Plant Sciences
Le Yang, Linchao Xia, Yi Zeng, Qingquan Han, Sheng Zhang
Summary: This review summarizes the mechanisms and methods of grafted plants' resistance to drought, including adaptive changes in root, stem, and leaf morphology, regulation of stomatal closure, activation of osmoregulation, enhancement of antioxidant systems, and regulation of phytohormones and gene expression. Additionally, it highlights the importance of phytohormone interactions and the establishment of graft communication through genetic materials.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Agronomy
Liangjing Cao, Mingjie Lyu, Jingyi Wang, Xuan Wang, Xinchang Li, Ruilian Jing, Jun Liu, Xinwen Hu
Summary: This study identified a large number of gene polymorphisms and mutations in two popular winter wheat cultivars and found time-point specific and cultivar-preferential responsive gene expression patterns related to abiotic stress response. Unexpected pathways associated with stress responses were also discovered.
Article
Plant Sciences
Kora Vyse, Stephanie Schaarschmidt, Alexander Erban, Joachim Kopka, Ellen Zuther
Summary: This study investigates the metabolic and transcriptomic changes in plants during cold priming and triggering. The research findings suggest that genes involved in cell wall remodeling and stress response regulation are induced during triggering, while the expression of late embryogenesis abundant proteins and antifreeze proteins is higher during priming. Moreover, the study indicates that a cold triggering stimulus might be perceived as a milder stress compared to priming in plants.
PHYSIOLOGIA PLANTARUM
(2022)
Review
Plant Sciences
Shehzad Iqbal, Xiukang Wang, Iqra Mubeen, Muhammad Kamran, Iqra Kanwal, Gonzalo A. Diaz, Aqleem Abbas, Aasma Parveen, Muhammad Nauman Atiq, Huda Alshaya, Tarek K. Zin El-Abedin, Shah Fahad
Summary: Human activities have triggered global warming, causing drought stresses that affect both animals and plants. To minimize the impact of drought stress on plants, it is crucial to establish a plant feedback mechanism of resistance to drought. This mechanism includes physical and physiological changes as well as molecular processes such as signal transduction and reactive clearance of oxygen. Additionally, microorganisms and the application of certain substances play an important role in enhancing drought resistance in plants.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Plant Sciences
Nilesh Vikram Lande, Pragya Barua, Dipak Gayen, Vijay Wardhan, Theboral Jeevaraj, Sunil Kumar, Subhra Chakraborty, Niranjan Chakraborty
Summary: The study of a dehydration-responsive chloroplast proteome in chickpea identified and investigated the uncharacterized protein CaPDZ1, which plays an important role in PSII complex assembly and/or repair. CaPDZ1 interacts with PSII-associated proteins and is expressed preferentially in photosynthetic tissues, showing multiple abundance under dehydration stress.
PHYSIOLOGIA PLANTARUM
(2022)
Article
Biochemistry & Molecular Biology
Zhijun Wang, Yanjun Li, Qianhao Zhu, Liwen Tian, Feng Liu, Xinyu Zhang, Jie Sun
Summary: In this study, the molecular mechanisms underlying the varietal difference in Mepiquat chloride (MC) sensitivity in cotton plants were investigated using transcriptome analysis. The results revealed that signal transduction of phytohormones, biosynthesis of gibberellins (GAs) and brassinosteroids (BRs), and profiles of transcription factors (TFs) were differentially affected by MC in the two cotton varieties. These findings indicate that although the same or similar biological pathways are influenced by MC treatment in cotton plants, the extent of effect varies, leading to different phenotypic outcomes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Plant Sciences
Huimin Zhao, Yani Niu, Hao Dong, Yaqi Jia, Yucheng Wang
Summary: The study identified two S1Fa-like TF genes, PtS1Fa1 and PtS1Fa2, in Populus trichocarpa. While PtS1Fa1 did not show significant effects, overexpression of PtS1Fa2 increased antioxidant activity and reduced ROS accumulation, playing a crucial role in drought tolerance in the plant.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Sapna Badhan, Andrew S. Ball, Nitin Mantri
Summary: The current genome editing system CRISPR/Cas9 has been proven effective in plant applications, with the DNA-free editing showing promise in achieving targeted mutagenesis in chickpea. By selecting drought tolerance-related genes 4CL and RVE7 for editing in chickpea protoplast, this study demonstrated high efficiency in editing the RVE7 gene, providing insights into gene functions under drought stress in chickpea.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Nutrition & Dietetics
Huong Thi Lan Nguyen, Stefan Kasapis, Nitin Mantri
Summary: The study compared the effects of Manuka honey and newly developed honeys on oxidative stress and cholesterol homeostasis, showing that Arjuna, Guggul, and Manuka honeys had significant antioxidant activities and reduced total cholesterol levels, while Jiaogulan honey exhibited the most cytotoxic effects.
Review
Oncology
Kanika Singh, Nazim Nassar, Ava Bachari, Ellen Schanknecht, Srinivasareddy Telukutla, Roby Zomer, Terrence J. Piva, Nitin Mantri
Summary: Prostate cancer is the second most commonly diagnosed cancer in males, and recent evidence suggests that cannabinoids may serve as powerful regulators of cell growth and differentiation. Research over the past two decades has shown that cannabinoids not only have palliative effects, but also hold promising potential as antitumor agents in a variety of cancers, including prostate cancer. This analysis may offer insights into the selection and development of specific cannabinoids for use in antitumor drugs for the treatment of prostate cancer.
Review
Cell Biology
Uday Chand Jha, Harsh Nayyar, Nitin Mantri, Kadambot H. M. Siddique
Summary: Noncoding RNAs play a critical role in plant growth, development, and stress responses, interacting with DNA, RNA, and proteins to modulate target genes, yet the regulatory mechanisms controlling these processes are still not well understood.
Article
Nutrition & Dietetics
Mayank Kaashyap, Marc Cohen, Nitin Mantri
Summary: Kombucha, a fermented tea, has potential health benefits due to its microbial communities beneficial for the human gut. The study identified previously undescribed microbial species in kombucha, with Acetobacter, Komagataeibacter and Starmerella having potential roles in preventing conditions like diabetes and obesity. Additionally, kombucha has high protein and phenolic content, low sugar content, making it a powerful probiotic with commercial value and immense health benefits.
Review
Pharmacology & Pharmacy
Haleh Mahmoudinoodezh, Srinivasa Reddy Telukutla, Sukhvir Kaur Bhangu, Ava Bachari, Francesca Cavalieri, Nitin Mantri
Summary: Recent studies have shown increased interest in the scientific community regarding the use of Cannabis sativa plant and its extracts for medicinal purposes. Due to their characteristics, cannabinoids are prone to degradation in solution. Thus, various delivery methods, including topical and transdermal, have been developed to enhance their bioavailability and stability. These methods have the potential to eliminate the psychotropic effects of cannabinoids.
Article
Plant Sciences
Mayank Kaashyap, Rebecca Ford, Anita Mann, Rajeev K. Varshney, Kadambot H. M. Siddique, Nitin Mantri
Summary: Salinity is a significant problem for salt-sensitive chickpea, and understanding the molecular mechanisms under salt stress is essential. Transcriptomic analysis of two genotypes revealed differentially expressed genes associated with salt tolerance, including genes involved in flowering time, pollen development, and transcription regulation. These genes can be potential candidates for improving salt tolerance in chickpea.
Article
Food Science & Technology
Alka Rani, Charles Chinyere Dike, Nitin Mantri, Andrew Ball
Summary: This study developed a rapid and reliable method for the detection of viable Escherichia coli O157:H7 using recombinase polymerase amplification (RPA) combined with propidium monoazide (PMAxx). The assay was able to differentiate between viable/dead bacteria and detect VBNC cells. It showed good performance in terms of detection limit, applicability, and pH stability.
Review
Chemistry, Medicinal
T. Srinivasa Reddy, Roby Zomer, Nitin Mantri
Summary: Medical cannabis has gained significant attention for its potential benefits in managing pain, anxiety, depression, and neurological disorders. The major phytocannabinoids derived from the cannabis plant, THC and CBD, have shown pharmacological and therapeutic properties. In particular, they have been studied for their use in cancer treatment due to their palliative effects and anticancer activities. However, their poor solubility and bioavailability limit their clinical application, thus nanotechnology-based drug delivery strategies are being developed to improve their efficacy.
PHYTOTHERAPY RESEARCH
(2023)
Article
Agronomy
Minna Yu, Peng Sun, Xinyi Huang, Zhuoyue Zha, Xin Wang, Nitin Mantri, Heqiang Lou, Bo Jiang, Zonggen Shen, Yanfang Sun, Hongfei Lu
Summary: The effects of CO2, temperature, and nitrogen supply on photosynthesis, root growth, and nitrogen allocation in strawberries were investigated. Elevated CO2 reduced photosynthetic rates and nitrogen concentration in leaves, accelerated leaf senescence, and increased root growth and nitrogen use efficiency. However, when nitrogen was supplied together with elevated CO2, root nitrogen concentration decreased but total root dry weight increased.
Article
Cell Biology
Ava Bachari, Nazim Nassar, Srinivasareddy Telukutla, Roby Zomer, Chaitali Dekiwadia, Terrence J. Piva, Nitin Mantri
Summary: Melanoma, an aggressive form of skin cancer, is resistant to advanced cancer treatments. Studies have shown that Cannabis sativa extracts exhibit potential anticancer effects against melanoma cells. However, further research is needed to evaluate their safety, efficacy, and clinical applications.
Review
Biochemistry & Molecular Biology
Deepak A. Yaraguppi, Zabin K. Bagewadi, Ninganagouda R. Patil, Nitin Mantri
Summary: This comprehensive review examines iturin, a cyclic lipopeptide originating from Bacillus subtilis and related bacteria. These compounds have potent inhibitory effects against plant disease-causing bacteria and fungi, making them valuable in bio-pesticides and mycosis treatment. Additionally, iturin exhibits diverse features such as anticancer and hemolytic effects, and finds applications across industries such as food, petroleum, pharmaceuticals, and cosmetics.
Review
Medicine, Research & Experimental
Ava Bachari, Nazim Nassar, Ellen Schanknecht, Srinivasareddy Telukutla, Terrence Jerald Piva, Nitin Mantri
Summary: This article provides an overview of the pathophysiology of melanoma, current pharmacotherapy, and the challenges associated with different pharmacological approaches. It also highlights the utility of cannabinoids as an additive remedy for melanoma.
WIRES MECHANISMS OF DISEASE
(2023)
Review
Biochemistry & Molecular Biology
Ellen Schanknecht, Ava Bachari, Nazim Nassar, Terrence Piva, Nitin Mantri
Summary: Melanoma is a deadly and physically impairing disease with ongoing treatment deficiencies. Current treatment regimens face pitfalls, with low five-year survival rates for patients with advanced metastatic invasion. Polyphenolic compounds, including cannabinoids, terpenoids, and flavonoids, show promising potential for anti-cancer, anti-inflammatory, and palliative utility. Cannabis sativa, with its medicinal compounds, could offer considerable relief for melanoma sufferers and should be further evaluated pharmacologically.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Food Science & Technology
Alka Rani Batra, Charles Chinyere Dike, Nitin Mantri, Andrew S. Ball
Summary: This study compares the application of RPA-LFA with PCR, qPCR, and LAMP in the diagnosis of E. coli O157:H7. The results show no significant difference in specificity among the four methods, but RPA-LFA performs the best in terms of sensitivity. The developed nitrocellulose paper strips combined with RPA can detect contamination in less than 25 minutes.
Article
Plant Sciences
Wanli You, Jinglin Zhang, Xueyin Ru, Feng Xu, Zhengguo Wu, Peng Jin, Yonghua Zheng, Shifeng Cao
Summary: This study investigated the effect of calcium chloride (CaCl2) treatment on GABA accumulation in fresh-cut cantaloupe and the underlying mechanisms. The results showed that CaCl2 treatment increased GABA content and the activities of GAD and SSADH enzymes, while reducing glutamate content and GABA-T activity. Additionally, CaCl2 treatment upregulated the expressions of CmCML11 and CmCAMTA5, as well as several GABA shunt genes, through the transcriptional activation by CmCAMTA5. Furthermore, the interaction between CmCML11 and CmCAMTA5 enhanced the transcriptional activation of GABA shunt genes. Overall, this study reveals that CaCl2 treatment promotes GABA accumulation in fresh-cut cantaloupe through the combined effect of CmCML11 and CmCAMTA5 in regulating the expressions of GABA shunt genes.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)
Article
Plant Sciences
Min Wang, Yupeng Wang, Xiaohui Wang, Guangwei Wei, Huiyi Yang, Xi Yang, Tinghai Shen, Huijie Qu, Sheng Fang, Ziming Wu
Summary: This study identified the high nitrogen use efficiency (NUE) black sesame variety 17-156 and analyzed its underlying physiological and molecular mechanisms. The results showed that 17-156 possesses a sophisticated nitrogen metabolizing machinery to uptake and assimilate higher quantities of inorganic nitrogen, simultaneously improving carbon metabolism and growth. Many important genes were up-regulated in 17-156 under high nitrogen condition. Additionally, 38 potential candidate genes were identified for future studies to improve sesame's NUE. These findings provide valuable resources for understanding the regulatory network of nitrogen metabolism and developing sesame cultivars with improved NUE.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)
Article
Plant Sciences
He Dong, Chongmei Xu, Chengtao Zhang, Li Zhang, Yaqin Yao, Suiqi Zhang
Summary: The study found that short cells in maize leaves not only improve leaf mechanical support and photosynthetic performance, enhance drought resistance, but also participate in stomatal regulation.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)
Article
Plant Sciences
Na Liu, Wenyan Shang, Mengxin Guan, Jibin Xiao, Guangxiang Tian, Baozhan Ma, Wenjing Shang, Xu Li, Shijia Zhao, Chuang Li, Kun Cheng, Wenming Zheng
Summary: This study cloned the full-length cDNA sequence of TaSPX3 gene in wheat and found that TaSPX3 responds to low phosphorus stress in multiple wheat genotypes. Overexpressing TaSPX3 can alleviate phosphorus deficiency symptoms and promote plant growth in Arabidopsis. The study also revealed the interaction of TaSPX3 with other genes related to the phosphorus starvation signaling pathway.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)
Article
Plant Sciences
Kongyuan Wu, Lizhen Wang, Zihan Wu, Ziqing Liu, Zengfei Li, Jun Shen, Shengjie Shi, Hong Liu, Christopher Rensing, Renwei Feng
Summary: Selenium (Se) can reduce uptake and translocation of cadmium (Cd) in plants by regulating root morphology. This study investigated the effects of Se(IV) on root exudates, root morphology, root endogenous hormones, and Cd uptake efficiency in rice under Cd stress. The results showed that Se(IV) significantly reduced Cd concentrations in shoots and roots, and decreased Cd uptake efficiency via root hairs. Se(IV) also affected root morphology, root exudates, and the synthesis of hormones like IAA and JA. However, transcriptome analysis revealed no upregulated differentially expressed genes (DEGs) in IAA synthesis.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)
Article
Plant Sciences
Di Wang, Huaifang Zhang, Xuefei Hu, Haizhen Zhang, Shuang Feng, Aimin Zhou
Summary: This study identified a cell number regulator gene called SlCNR8 in willow, which enhances resistance to trace metals in transgenic poplar seedlings. SlCNR8 reduces Cd uptake and accumulation, and can be used as a candidate gene for genetic improvement of phytostabilisation of trace metals.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2024)
