Potential high-frequency off-target mutagenesis induced by CRISPR/Cas9 in Arabidopsis and its prevention
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Potential high-frequency off-target mutagenesis induced by CRISPR/Cas9 in Arabidopsis and its prevention
Authors
Keywords
Genome editing, CRISPR/Cas9, Off-target effects, Editing specificity, Editing efficiency
Journal
PLANT MOLECULAR BIOLOGY
Volume 96, Issue 4-5, Pages 445-456
Publisher
Springer Nature
Online
2018-02-23
DOI
10.1007/s11103-018-0709-x
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Gene Targeting by Homology-Directed Repair in Rice Using a Geminivirus-Based CRISPR/Cas9 System
- (2017) Mugui Wang et al. Molecular Plant
- Enhanced proofreading governs CRISPR–Cas9 targeting accuracy
- (2017) Janice S. Chen et al. NATURE
- CRISPR-S: an active interference element for a rapid and inexpensive selection of genome-edited, transgene-free rice plants
- (2017) Hai-Ping Lu et al. PLANT BIOTECHNOLOGY JOURNAL
- High-efficiency gene targeting in hexaploid wheat using DNA replicons and CRISPR/Cas9
- (2017) Javier Gil-Humanes et al. PLANT JOURNAL
- Efficient DNA-free genome editing of bread wheat using CRISPR/Cas9 ribonucleoprotein complexes
- (2017) Zhen Liang et al. Nature Communications
- MISSA 2.0: an updated synthetic biology toolbox for assembly of orthogonal CRISPR/Cas systems
- (2017) Hai-Yan Zhang et al. Scientific Reports
- Methods for Optimizing CRISPR-Cas9 Genome Editing Specificity
- (2016) Josh Tycko et al. MOLECULAR CELL
- High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects
- (2016) Benjamin P. Kleinstiver et al. NATURE
- Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
- (2016) John G Doench et al. NATURE BIOTECHNOLOGY
- Defining and improving the genome-wide specificities of CRISPR–Cas9 nucleases
- (2016) Shengdar Q. Tsai et al. NATURE REVIEWS GENETICS
- An Effective Strategy for Reliably Isolating Heritable and Cas9 -Free Arabidopsis Mutants Generated by CRISPR/Cas9-Mediated Genome Editing
- (2016) Xiuhua Gao et al. PLANT PHYSIOLOGY
- Genome editing in maize directed by CRISPR–Cas9 ribonucleoprotein complexes
- (2016) Sergei Svitashev et al. Nature Communications
- Achieving Plant CRISPR Targeting that Limits Off-Target Effects
- (2016) Jeffrey D. Wolt et al. Plant Genome
- Genome-Wide Assessment of Efficiency and Specificity in CRISPR/Cas9 Mediated Multiple Site Targeting in Arabidopsis
- (2016) Brenda A. Peterson et al. PLoS One
- How specific is CRISPR/Cas9 really?
- (2015) Henriette O’Geen et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- DNA-free genome editing in plants with preassembled CRISPR-Cas9 ribonucleoproteins
- (2015) Je Wook Woo et al. NATURE BIOTECHNOLOGY
- Highly efficient heritable plant genome engineering using Cas9 orthologues fromStreptococcus thermophilusandStaphylococcus aureus
- (2015) Jeannette Steinert et al. PLANT JOURNAL
- Auxin binding protein 1 (ABP1) is not required for either auxin signaling orArabidopsisdevelopment
- (2015) Yangbin Gao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Boosting CRISPR/Cas9 multiplex editing capability with the endogenous tRNA-processing system
- (2015) Kabin Xie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rationally engineered Cas9 nucleases with improved specificity
- (2015) I. M. Slaymaker et al. SCIENCE
- Egg cell-specific promoter-controlled CRISPR/Cas9 efficiently generates homozygous mutants for multiple target genes in Arabidopsis in a single generation
- (2015) Zhi-Ping Wang et al. GENOME BIOLOGY
- Embryonic lethality of Arabidopsis abp1-1 is caused by deletion of the adjacent BSM gene
- (2015) Xinhua Dai et al. Nature Plants
- A CRISPR/Cas9 toolkit for multiplex genome editing in plants
- (2014) Hui-Li Xing et al. BMC PLANT BIOLOGY
- The CRISPR/Cas9 system produces specific and homozygous targeted gene editing in rice in one generation
- (2014) Hui Zhang et al. PLANT BIOTECHNOLOGY JOURNAL
- Both CRISPR/Cas-based nucleases and nickases can be used efficiently for genome engineering inArabidopsis thaliana
- (2014) Friedrich Fauser et al. PLANT JOURNAL
- Multigeneration analysis reveals the inheritance, specificity, and patterns of CRISPR/Cas-induced gene modifications in Arabidopsis
- (2014) Z. Feng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Staying on target with CRISPR-Cas
- (2013) Dana Carroll NATURE BIOTECHNOLOGY
- DNA targeting specificity of RNA-guided Cas9 nucleases
- (2013) Patrick D Hsu et al. NATURE BIOTECHNOLOGY
- High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
- (2013) Yanfang Fu et al. NATURE BIOTECHNOLOGY
- RNA-Guided Human Genome Engineering via Cas9
- (2013) P. Mali et al. SCIENCE
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
- (2012) M. Jinek et al. SCIENCE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now