Journal
PHYTOCHEMISTRY LETTERS
Volume 26, Issue -, Pages 125-129Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.phytol.2018.05.031
Keywords
Zanthoxylum zanthoxyloides; Rutaceae; Cytotoxicity; Alkamides; Zanthoamides
Categories
Funding
- Commonwealth Commission
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Three new alkamides, zanthoamides G-I (1-3), together with ten known compounds, araliopsine, skimmianine, N-methylplatydesminium cation, isoplatydesmine, myrtopsine, atanine, N-methylatanine, sesamin, hesperetin and hesperidin, were isolated from the fruits of Zanthoxylum zanthoxyloides. Their structures were elucidated by spectroscopic means. All isolated compounds were assessed for their cytotoxicity against A549, MCF7, PC3 and PNT2 cell lines. Among the alkamides, only zanthoamide G (1) showed low level of cytotoxicity against MCF7 cells.
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