Review
Cardiac & Cardiovascular Systems
Pratik Lamichhane, Kailash Mani Pokhrel, Pashupati Pokharel, Bijay Bhandari, Pratima Lamichhane, Prakash Raj Regmi
Summary: The prevalence of rheumatic heart disease (RHD) remains high in the South Asian population, and recent studies using echocardiographic screening have identified subclinical cases, highlighting the significant burden of the disease in this region. More population-based echocardiography screening studies in each country in South Asia are needed to accurately estimate the prevalence of the disease.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2022)
Review
Genetics & Heredity
Frida Toft-Nielsen, Frida Emanuelsson, Marianne Benn
Summary: The prevalence of FH varies across different ethnicities, ranging from 0.25% (1:400) to 0.52% (1:192), with the highest rates seen among black and brown populations and the lowest among Asians. These differences suggest that targeted screening among subpopulations may increase case identification and prevention opportunities.
FRONTIERS IN GENETICS
(2022)
Review
Multidisciplinary Sciences
Hoimonty Mazumder, Kazi Faria Islam, Farzana Rahman, Easter Protiva Gain, Nobonita Saha, Irfath Sharmin Eva, Md Monir Hossain Shimul, Jyoti Das, M. Mahbub Hossain
Summary: This meta-analytic review aimed to estimate the prevalence of anemia among people with DM in South Asia. The study found that the prevalence of anemia among diabetic people in South Asia was 45%, with higher rates in females and older age groups. The study calls for further clinical and public health research to understand the context-specific epidemiological insights and evidence in this region.
Article
Medicine, General & Internal
Aristeidis H. Katsanos, Lina Palaiodimou, Christopher Price, Marios Themistocleous, Robin Lemmens, Ioannis Michopoulos, Marios K. Georgakis, Christian Weimar, Peter Kelly, Georgios Tsivgoulis
Summary: Colchicine treatment decreases the stroke risk in patients with a history of atherosclerotic cardiovascular disease, with no significant difference observed in different subgroups.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Nutrition & Dietetics
Zhangling Chen, Mavra Ahmed, Vanessa Ha, Katherine Jefferson, Vasanti Malik, Paula A. B. Ribeiro, Priccila Zuchinali, Jean-Philippe Drouin-Chartier
Summary: The overall conclusion from the study is that total dairy consumption is associated with a modestly lower risk of hypertension, CHD, and stroke; however, low-fat dairy consumption is more strongly associated with lower risk, particularly in relation to hypertension and stroke. High-fat dairy consumption also shows a lower risk of stroke.
ADVANCES IN NUTRITION
(2022)
Article
Medicine, General & Internal
Seungji Kang, Seuhyun Eum, Yoonkyung Chang, Ai Koyanagi, Louis Jacob, Lee Smith, Jae Il Shin, Tae-Jin Song
Summary: According to the Global Burden of Disease study, the DALYs of neurological diseases in South-East Asia and Western Pacific regions were 64.4 million and 85.0 million in 2019, respectively. Stroke, migraine, Alzheimer's disease and other dementias had the highest DALYs in these regions in 2019.
Review
Multidisciplinary Sciences
Ahmad Adebayo Irekeola, Nurul Adila Malek, Yusuf Wada, Nazri Mustaffa, Nur Izat Muhamad, Rafidah Hanim Shueb
Summary: This study provides a comprehensive overview of HCV genotype and subtype distribution in Southeast Asia (SEA), revealing that genotype 1 and 3 are the most common in the region, with genotype 6 becoming more prevalent after 2000. The most prevalent subtypes identified were 1b, 1a, and 3a.
Review
Medicine, General & Internal
Martin Ackah, Cynthia Osei Yeboah, Louise Ameyaw
Summary: This study aims to systematically review and meta-analyze the risk factors for in-hospital stroke mortality in sub-Saharan Africa, in order to provide targeted research. The pooled 30-day in-hospital stroke mortality rate will be analyzed, with meta-regression used to assess associated factors, as well as subgroup and sensitivity analyses conducted for further insights.
Article
Cardiac & Cardiovascular Systems
Daniel Bos, Banafsheh Arshi, Quirijn J. A. van den Bouwhuijsen, M. Kamran Ikram, Mariana Selwaness, Meike W. Vernooij, Maryam Kavousi, Aad van der Lugt
Summary: This study found that hemorrhage in carotid atherosclerotic plaque is an independent risk factor for stroke and coronary heart disease.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Review
Peripheral Vascular Disease
Karen C. Schliep, Hailey Mclean, Bin Yan, Fares Qeadan, Lauren H. Theilen, Adam de Havenon, Jennifer J. Majersik, Truls Ostbye, Surendra Sharma, Michael W. Varner
Summary: Previous meta-analyses have shown that women with a history of hypertensive disorders of pregnancy (HDP) have a 2- to 4-fold increased risk of later cardiovascular disease. This study aims to summarize the evidence for the impact of HDP on dementia and explore the unique associations between HDP and dementia subtypes.
Article
Cardiac & Cardiovascular Systems
Martin O'Donnell, Graeme J. Hankey, Sumathy Rangarajan, Siu Lim Chin, Purnima Rao-Melacini, John Ferguson, Denis Xavier, Liu Lisheng, Hongye Zhang, Prem Pais, Patricio Lopez-Jaramillo, Albertino Damasceno, Peter Langhorne, Annika Rosengren, Antonio L. Dans, Ahmed Elsayed, Alvaro Avezum, Charles Mondo, Andrew Smyth, Conor Judge, Hans-Christoph Diener, Danuta Ryglewicz, Anna Czlonkowska, Nana Pogosova, Christian Weimar, Romana Iqbal, Rafael Diaz, Khalid Yusoff, Afzalhussein Yusufali, Aytekin Oguz, Xingyu Wang, Ernesto Penaherrera, Fernando Lanas, Okechukwu Samuel Ogah, Adensola Ogunniyi, Helle K. Iversen, German Malaga, Zvonko Rumboldt, Shahram Oveisgharan, Fawaz AlHussain, Magazi Daliwonga, Yongchai Nilanont, Salim Yusuf
Summary: The study found that deficits in knowledge, detection, and treatment of hypertension contribute to an increased risk of stroke, younger age of onset, and a larger proportion of intracerebral hemorrhage in lower-income countries.
Review
Peripheral Vascular Disease
Yuda Turana, Jeslyn Tengkawan, Yook Chin Chia, Michael Nathaniel, Ji-Guang Wang, Apichard Sukonthasarn, Chen-Huan Chen, Huynh Van Minh, Peera Buranakitjaroen, Jinho Shin, Saulat Siddique, Jennifer M. Nailes, Sungha Park, Boon Wee Teo, Jorge Sison, Arieska Ann Soenarta, Satoshi Hoshide, Jam Chin Tay, Guru Prasad Sogunuru, Yuqing Zhang, Narsingh Verma, Tzung-Dau Wang, Kazuomi Kario
Summary: Stroke is a major cause of disability and vascular death in Asia and globally. Studies in Asia have found that hypertension is the most prevalent risk factor for stroke, with blood pressure levels and variability also playing a role. Post-stroke cognitive impairment is a significant public health concern that is often overlooked despite its increasing prevalence. Preventing recurrence and increasing awareness and adherence to hypertension treatment are key goals in Asia.
JOURNAL OF CLINICAL HYPERTENSION
(2021)
Review
Cardiac & Cardiovascular Systems
Xuejun Yin, Anthony Rodgers, Adam Perkovic, Liping Huang, Ka-Chun Li, Jie Yu, Yangfeng Wu, J. H. Y. Wu, Matti Marklund, Mark D. Huffman, J. Jaime Miranda, Gian Luca Di Tanna, Darwin Labarthe, Paul Elliott, Maoyi Tian, Bruce Neal
Summary: The study found that salt substitutes have consistent effects on reducing blood pressure across different geographic regions and populations. The blood pressure-mediated protective effects on clinical outcomes are likely applicable to different population subgroups and countries worldwide.
Review
Medicine, General & Internal
Rami Z. Morsi, Yuan Zhang, Julian Carrion-Penagos, Harsh Desai, Elie Tannous, Sachin Kothari, Assem M. Khamis, Andrea J. Darzi, Ammar Tarabichi, Reena Bastin, Layal Hneiny, Sonam Thind, Elisheva Coleman, James R. Brorson, Scott Mendelson, Ali Mansour, Shyam Prabhakaran, Tareq Kass-Hout
Summary: This article presents the current published guidelines and meta-analyses comparing endovascular thrombectomy (EVT) alone versus EVT with bridging intravenous thrombolysis (IVT), suggesting that EVT alone is non-inferior to EVT with bridging thrombolysis in achieving favourable functional outcome. The study aims to systematically update the evidence, perform a meta-analysis of randomized trials, and conduct an economic evaluation comparing both strategies.
Review
Clinical Neurology
Robin Brown, Audrey Low, Hugh S. Markus
Summary: The progression rate of white matter hyperintensities (WMHs) varies depending on the characteristics of the population being studied, with factors such as age, baseline lesion volume, hypertension, and smoking being associated with WMH growth. Sample sizes for clinical trials using WMH as an outcome measure will vary greatly based on patient population selection and baseline lesion volume.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2021)
Review
Peripheral Vascular Disease
James E. Sharman, Isabella Tan, George S. Stergiou, Carolina Lombardi, Francesca Saladini, Mark Butlin, Raj Padwal, Kei Asayama, Alberto Avolio, Tammy M. Brady, Alan Murray, Gianfranco Parati
Summary: Automated oscillometric blood pressure measuring devices have replaced manual auscultatory blood pressure measurement by mercury sphygmomanometers in clinical settings. These validated devices provide similar blood pressure values to manual measurement, making them the recommended standard for hypertension diagnosis and management globally.
JOURNAL OF HUMAN HYPERTENSION
(2023)
Review
Peripheral Vascular Disease
Dean S. Picone, Raj Padwal, George S. Stergiou, Jordana B. Cohen, Richard J. McManus, Siegfried Eckert, Kei Asayama, Neil Atkins, Michael Rakotz, Cintia Lombardi, Tammy M. Brady, James E. Sharman
Summary: Clinically validated, automated arm-cuff blood pressure measuring devices are recommended for accurate measurement. However, most devices available for consumers lack proper validation, which increases the risk of misdiagnosis and mismanagement of blood pressure. Validated device lists have been developed to address this issue, but there are still challenges to overcome.
JOURNAL OF HUMAN HYPERTENSION
(2023)
Article
Peripheral Vascular Disease
Shingo Nakayama, Michihiro Satoh, Hirohito Metoki, Takahisa Murakami, Yukako Tatsumi, Kei Asayama, Azusa Hara, Takuo Hirose, Megumi Tsubota-Utsugi, Masahiro Kikuya, Takefumi Mori, Atsushi Hozawa, Yutaka Imai, Takayoshi Ohkubo
Summary: This study investigated the association between ambulatory blood pressure and the risk of home hypertension in a normotensive population. The results showed that considering ambulatory blood pressure can improve the accuracy of the 10-year prediction model for home hypertension risk.
AMERICAN JOURNAL OF HYPERTENSION
(2023)
Article
Geriatrics & Gerontology
Takuma Shibuki, Miho Iida, Sei Harada, Suzuka Kato, Kazuyo Kuwabara, Aya Hirata, Mizuki Sata, Minako Matsumoto, Yusuke Osawa, Tomonori Okamura, Daisuke Sugiyama, Toru Takebayashi
Summary: This study aimed to examine the association between sleep duration and quality and sarcopenia among older community-dwellers in Japan. The results showed that long sleep duration was positively associated with sarcopenia, especially low muscle strength and low physical performance. However, insomnia was not associated with sarcopenia or its components in long sleepers.
ARCHIVES OF GERONTOLOGY AND GERIATRICS
(2023)
Review
Peripheral Vascular Disease
Kei Asayama, Katarzyna Stolarz-Skrzypek, Wen-Yi Yang, Tine W. Hansen, Jana Brguljan-Hitij, Augustine N. Odili, Yan Li, Jan A. Staessen
Summary: The International Databases on Ambulatory (IDACO) and Home (IDHOCO) Blood Pressure in Relation to Cardiovascular Outcome conducted a meta-analysis which found that 24-hour and nighttime blood pressure levels are the best predictors of adverse health outcomes. They also established corresponding thresholds for home and ambulatory blood pressure. The study emphasized the importance of out-of-office blood pressure monitoring in tackling the hypertension pandemic.
HYPERTENSION RESEARCH
(2023)
Article
Peripheral Vascular Disease
Gianfranco Parati, Grzegorz Bilo, Anastasios Kollias, Martino Pengo, Juan Eugenio Ochoa, Paolo Castiglioni, George S. Stergiou, Giuseppe Mancia, Kei Asayama, Roland Asmar, Alberto Avolio, Enrico G. Caiani, Alejandro De La Sierra, Eamon Dolan, Andrea Grillo, Przemyslaw Guzik, Satoshi Hoshide, Geoffrey A. Head, Yutaka Imai, Eeva Juhanoja, Thomas Kahan, Kazuomi Kario, Vasilios Kotsis, Reinhold Kreutz, Konstantinos G. Kyriakoulis, Yan Li, Efstathios Manios, Anastasia S. Mihailidou, Pietro Amedeo Modesti, Stefano Omboni, Paolo Palatini, Alexandre Persu, Athanasios D. Protogerou, Francesca Saladini, Paolo Salvi, Pantelis Sarafidis, Camilla Torlasco, Franco Veglio, Charalambos Vlachopoulos, Yuqing Zhang
Summary: Blood pressure is not static, but fluctuates continuously due to environmental and behavioral factors. Increased blood pressure variability may indicate impaired cardiovascular regulation and is associated with increased mortality and disease incidence.
JOURNAL OF HYPERTENSION
(2023)
Review
Peripheral Vascular Disease
Keiko Kondo, Katsuyuki Miura, Tomonori Okamura, Akira Okayama, Hirotsugu Ueshima
Summary: Dietary habits significantly impact healthy life expectancy by affecting cardiovascular disease risk and chronic diseases. The NIPPON DATA80/90 cohort study found that a dietary pattern characterized by high intake of fruits, vegetables, fish (n-3 polyunsaturated fatty acids), and dietary fiber, and low intake of salt and sodium-to-potassium ratio, is associated with a lower risk of cardiovascular disease mortality. These findings can inform effective strategies for cardiovascular disease prevention.
JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS
(2023)
Article
Public, Environmental & Occupational Health
Hideki Nagata, Katsuyuki Miura, Sachiko Tanaka, Aya Kadota, Takehito Hayakawa, Keiko Kondo, Akira Fujiyoshi, Naoyuki Takashima, Yoshikuni Kita, Akira Okayama, Tomonori Okamura, Hirotsugu Ueshima
Summary: This study investigated the relationship between functional capacity and mortality risk among a population-based cohort of older residents in Japan. Impaired functional capacity was associated with a higher risk of all-cause mortality, with different factors playing a role for men and women.
JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Yiwei Liu, Aya Hirata, Tomonori Okamura, Daisuke Sugiyama, Takumi Hirata, Aya Kadota, Keiko Kondo, Takayoshi Ohkubo, Katsuyuki Miura, Akira Okayama, Hirotsugu Ueshima
Summary: The impact of resting heart rate on cardiovascular disease mortality varies according to serum albumin levels in the general Japanese population.
JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Multidisciplinary Sciences
Michihiro Satoh, Tomoya Yoshida, Hirohito Metoki, Takahisa Murakami, Yukako Tatsumi, Takuo Hirose, Kyosuke Takabatake, Megumi Tsubota-Utsugi, Azusa Hara, Kyoko Nomura, Kei Asayama, Masahiro Kikuya, Atsushi Hozawa, Yutaka Imai, Takayoshi Ohkubo
Summary: The long-term reproducibility of the white-coat effect is limited in the general population without antihypertensive treatment, and the change in the white-coat effect is mainly caused by office blood pressure variation.
SCIENTIFIC REPORTS
(2023)
Article
Peripheral Vascular Disease
Yukiko Okami, Queenie Chan, Katsuyuki Miura, Aya Kadota, Paul Elliott, Kamal Masaki, Akira Okayama, Nagako Okuda, Katsushi Yoshita, Naoko Miyagawa, Tomonori Okamura, Kiyomi Sakata, Shigeyuki Saitoh, Masaru Sakurai, Hideaki Nakagawa, Jeremiah Stamler, Hirotsugu Ueshima
Summary: This study aimed to compare the differences in serum lipids, especially particle size and fractions, between Japanese living in Japan and Japanese-Americans in Hawaii, and to examine the associated modifiable lifestyle factors. The results showed that Japanese had lower concentrations of HDL4, and higher fish intake was associated with lower HDL4 concentrations.
JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS
(2023)
Article
Peripheral Vascular Disease
Ayako Kunimura, Katsuyuki Miura, Hiroyoshi Segawa, Sayuki Torii, Keiko Kondo, Takashi Hisamatsu, Aya Kadota, Akira Fujiyoshi, Yuichiro Yano, Yoshihisa Nakagawa, Tomonori Okamura, Hirotsugu Ueshima, SESSA Res Grp
Summary: This study assessed the relationship between serum PCSK9 concentration and coronary artery calcium (CAC) prevalence in the general population. It found a significant association between serum PCSK9 concentration and CAC prevalence in men aged <60 years, but not in men aged 60-69 years or ≥70 years.
JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS
(2023)
Meeting Abstract
Peripheral Vascular Disease
Arisa Wada, Mai Kabayama, Kayo Godai, Michiko Kido, Sumiyo Hashimoto, Makiko Higashi, Hiromi Hatanaka, Takeshi Kikuchi, Takayuki Dodo, Kei Asayama, Takayoshi Ohkubo, Hiromi Rakugi, Yasuharu Tabara, Kei Kamide
JOURNAL OF HYPERTENSION
(2023)
Article
Peripheral Vascular Disease
Megumi Tsubota-Utsugi, Michihiro Satoh, Jun Watanabe, Jun Takebayashi, Tomoyuki Oki, Yukako Tatsumi, Kei Asayama, Masahiro Kikuya, Takahisa Murakami, Takuo Hirose, Hirohito Metoki, Azusa Hara, Kyoko Nomura, Atsushi Hozawa, Yoshitaka Tsubono, Yutaka Imai, Takayoshi Ohkubo
Summary: This study examined the association between hydrophilic and lipophilic antioxidant capacities of a Japanese diet and chronic kidney disease (CKD) risk. The findings suggest that a high intake of lipophilic antioxidants may be associated with a reduced risk of CKD, particularly in women. Achieving a balance between dietary antioxidant intake and pro-oxidants induced by unhealthy lifestyles may be crucial for preventing future kidney deterioration.
JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS
(2023)