Liposomal Irinotecan Accumulates in Metastatic Lesions, Crosses the Blood-Tumor Barrier (BTB), and Prolongs Survival in an Experimental Model of Brain Metastases of Triple Negative Breast Cancer

Effect of hesperidin on the pharmacokinetics of CPT-11 and its active metabolite SN-38 by regulating hepatic Mrp2 in rats

(2016) Xingdong Wang et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Comparative effectiveness of stereotactic radiosurgery versus whole-brain radiation therapy for patients with brain metastases from breast or non-small cell lung cancer

(2016) Lia M. Halasz et al.   CANCER

Quantitative Fluorescence Microscopy Measures Vascular Pore Size in Primary and Metastatic Brain Tumors

(2016) Rajendar K. Mittapalli et al.   CANCER RESEARCH

Dual HER2 Targeting with Trastuzumab and Liposomal-Encapsulated Doxorubicin (MM-302) Demonstrates Synergistic Antitumor Activity in Breast and Gastric Cancer

(2016) Christopher W. Espelin et al.   CANCER RESEARCH

Characterization of passive permeability at the blood–tumor barrier in five preclinical models of brain metastases of breast cancer

(2016) Chris E. Adkins et al.   CLINICAL & EXPERIMENTAL METASTASIS

Semi-automated rapid quantification of brain vessel density utilizing fluorescent microscopy

(2016) Kaci A. Bohn et al.   JOURNAL OF NEUROSCIENCE METHODS

ABCG2 and ABCB1 Limit the Efficacy of Dasatinib in a PDGF-B-Driven Brainstem Glioma Model

(2016) R. K. Mittapalli et al.   MOLECULAR CANCER THERAPEUTICS

Efficacy and pharmacokinetics of a modified acid-labile docetaxel-PRINT® nanoparticle formulation against non-small-cell lung cancer brain metastases

(2016) Maria Sambade et al.   Nanomedicine

NKTR-102 Efficacy versus irinotecan in a mouse model of brain metastases of breast cancer

(2015) Chris E. Adkins et al.   BMC CANCER

Cancer statistics, 2015

(2015) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Co-encapsulation of chrysophsin-1 and epirubicin in PEGylated liposomes circumvents multidrug resistance in HeLa cells

(2015) Yu-Li Lo et al.   CHEMICO-BIOLOGICAL INTERACTIONS

A Novel Preclinical Method to Quantitatively Evaluate Early-Stage Metastatic Events at the Murine Blood-Brain Barrier

(2014) C. E. Adkins et al.   Cancer Prevention Research

Preclinical Activity of Nanoliposomal Irinotecan Is Governed by Tumor Deposition and Intratumor Prodrug Conversion

(2014) A. V. Kalra et al.   CANCER RESEARCH

Lipid-based capsaicin-loaded nano-colloidal biocompatible topical carriers with enhanced analgesic potential and decreased dermal irritation

(2014) Kaisar Raza et al.   JOURNAL OF LIPOSOME RESEARCH

Pharmacokinetics, tumor accumulation and antitumor activity of nanoliposomal irinotecan following systemic treatment of intracranial tumors

(2014) Charles O Noble et al.   Nanomedicine

Capecitabine and lapatinib uptake in surgically resected brain metastases from metastatic breast cancer patients: a prospective study

(2014) Aki Morikawa et al.   NEURO-ONCOLOGY

Quantitative fluorescence microscopy provides high resolution imaging of passive diffusion and P-gp mediated efflux at the in vivo blood–brain barrier

(2013) Rajendar K. Mittapalli et al.   JOURNAL OF NEUROSCIENCE METHODS

Passive Tumor Targeting of Renal-Clearable Luminescent Gold Nanoparticles: Long Tumor Retention and Fast Normal Tissue Clearance

(2013) Jinbin Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Paclitaxel–Hyaluronic NanoConjugates Prolong Overall Survival in a Preclinical Brain Metastases of Breast Cancer Model

(2013) Rajendar K. Mittapalli et al.   MOLECULAR CANCER THERAPEUTICS

Anthracycline nano-delivery systems to overcome multiple drug resistance: A comprehensive review

(2013) Ping Ma et al.   Nano Today

P-glycoprotein mediated efflux limits substrate and drug uptake in a preclinical brain metastases of breast cancer model

(2013) Chris E. Adkins et al.   Frontiers in Pharmacology

The EPR effect for macromolecular drug delivery to solid tumors: Improvement of tumor uptake, lowering of systemic toxicity, and distinct tumor imaging in vivo

(2012) Hiroshi Maeda et al.   ADVANCED DRUG DELIVERY REVIEWS

Clinicopathologic features, patterns of recurrence, and survival among women with triple-negative breast cancer in the National Comprehensive Cancer Network

(2012) Nancy U. Lin et al.   CANCER

Epirubicin loaded with propylene glycol liposomes significantly overcomes multidrug resistance in breast cancer

(2012) Ying-Zheng Zhao et al.   CANCER LETTERS

Lapatinib plus capecitabine in patients with previously untreated brain metastases from HER2-positive metastatic breast cancer (LANDSCAPE): a single-group phase 2 study

(2012) Thomas Bachelot et al.   LANCET ONCOLOGY

Liposome Encapsulation of a Photochemical NO Precursor for Controlled Nitric Oxide Release and Simultaneous Fluorescence Imaging

(2012) Alexis D. Ostrowski et al.   MOLECULAR PHARMACEUTICS

Summary Report on the Graded Prognostic Assessment: An Accurate and Facile Diagnosis-Specific Tool to Estimate Survival for Patients With Brain Metastases

(2011) Paul W. Sperduto et al.   JOURNAL OF CLINICAL ONCOLOGY

Lapatinib Distribution in HER2 Overexpressing Experimental Brain Metastases of Breast Cancer

(2011) Kunal S. Taskar et al.   PHARMACEUTICAL RESEARCH

Heterogeneous Blood-Tumor Barrier Permeability Determines Drug Efficacy in Experimental Brain Metastases of Breast Cancer

(2010) P. R. Lockman et al.   CLINICAL CANCER RESEARCH

Delivering nanomedicine to solid tumors

(2010) Rakesh K. Jain et al.   Nature Reviews Clinical Oncology

Improved Pharmacokinetics and Efficacy of a Highly Stable Nanoliposomal Vinorelbine

(2008) D. C. Drummond et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS