Dual Effect of Histidine on Polysorbate 20 Stability: Mechanistic Studies
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Dual Effect of Histidine on Polysorbate 20 Stability: Mechanistic Studies
Authors
Keywords
free fatty acid, L-histidine, oxidation, peroxyl radical, Polysorbate 20
Journal
PHARMACEUTICAL RESEARCH
Volume 35, Issue 2, Pages -
Publisher
Springer Nature
Online
2018-01-17
DOI
10.1007/s11095-017-2321-1
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Degradation Mechanisms of Polysorbate 20 Differentiated by 18O-labeling and Mass Spectrometry
- (2016) Lin Zhang et al. PHARMACEUTICAL RESEARCH
- Key interactions of surfactants in therapeutic protein formulations: A review
- (2015) Tarik A. Khan et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Oxidative Degradation of Polysorbate Surfactants Studied by Liquid Chromatography–Mass Spectrometry
- (2015) Oleg V. Borisov et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Understanding Particle Formation: Solubility of Free Fatty Acids as Polysorbate 20 Degradation Byproducts in Therapeutic Monoclonal Antibody Formulations
- (2015) Nidhi Doshi et al. MOLECULAR PHARMACEUTICS
- Characterization and Stability Study of Polysorbate 20 in Therapeutic Monoclonal Antibody Formulation by Multidimensional Ultrahigh-Performance Liquid Chromatography–Charged Aerosol Detection–Mass Spectrometry
- (2014) Yi Li et al. ANALYTICAL CHEMISTRY
- Carbon-centered radicals add reversibly to histidine – implications
- (2014) Thomas Nauser et al. CHEMICAL COMMUNICATIONS
- Stabilisation of proteins via mixtures of amino acids during spray drying
- (2014) Ankur Ajmera et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Ester Hydrolysis of Polysorbate 80 in mAb Drug Product: Evidence in Support of the Hypothesized Risk After the Observation of Visible Particulate in mAb Formulations
- (2014) Steven R. Labrenz JOURNAL OF PHARMACEUTICAL SCIENCES
- Investigation of Histidine Stabilizing Effects on LDH During Freeze-Drying
- (2012) Anas Al-Hussein et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Toward Understanding Molecular Heterogeneity of Polysorbates by Application of Liquid Chromatography–Mass Spectrometry with Computer-Aided Data Analysis
- (2011) Oleg V. Borisov et al. ANALYTICAL CHEMISTRY
- Photosensitizers Form in Histidine Buffer and Mediate the Photodegradation of a Monoclonal Antibody
- (2011) Steven D. Stroop et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Site-Specific Tryptophan Oxidation Induced by Autocatalytic Reaction of Polysorbate 20 in Protein Formulation
- (2011) Xanthe M. Lam et al. PHARMACEUTICAL RESEARCH
- The Degradation of Polysorbates 20 and 80 and its Potential Impact on the Stability of Biotherapeutics
- (2011) Ravuri S. K. Kishore et al. PHARMACEUTICAL RESEARCH
- The Relative Rate of Immunoglobulin Gamma 1 Fragmentation
- (2010) Tim J. Kamerzell et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Degradation of Polysorbates 20 and 80: Studies on Thermal Autoxidation and Hydrolysis
- (2010) Ravuri S.K. Kishore et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Recent trends in stabilising peptides and proteins in pharmaceutical formulation – considerations in the choice of excipients
- (2009) Lene Jorgensen et al. Expert Opinion on Drug Delivery
- A Quantitative Kinetic Study of Polysorbate Autoxidation: The Role of Unsaturated Fatty Acid Ester Substituents
- (2009) Jia Yao et al. PHARMACEUTICAL RESEARCH
- Dual effects of Tween 80 on protein stability
- (2007) Wei Wang et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Polysorbates 20 and 80 Used in the Formulation of Protein Biotherapeutics: Structure and Degradation Pathways
- (2007) Bruce A. Kerwin JOURNAL OF PHARMACEUTICAL SCIENCES
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More