Ionophore and Biometal Modulation of P-glycoprotein Expression and Function in Human Brain Microvascular Endothelial Cells

Development and Validation of an In-Cell Western for Quantifying P-Glycoprotein Expression in Human Brain Microvascular Endothelial (hCMEC/D3) Cells

(2017) Mitchell P. McInerney et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Clioquinol Decreases Amyloid-β Burden and Reduces Working Memory Impairment in a Transgenic Mouse Model of Alzheimer's Disease

(2017) Cristina Grossi et al.   JOURNAL OF ALZHEIMERS DISEASE

The Effects of Copper on Brain Microvascular Endothelial Cells and Claudin Via Apoptosis and Oxidative Stress

(2016) Jian Wang et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

A Role for P-Glycoprotein in Clearance of Alzheimer Amyloid ? -Peptide from the Brain

(2016) Wei Wang et al.   Current Alzheimer Research

ABC transporters as mediators of drug resistance and contributors to cancer cell biology

(2016) Jamie I. Fletcher et al.   DRUG RESISTANCE UPDATES

Dynamic internalization and recycling of a metal ion transporter: Cu homeostasis and CTR1, the human Cu+uptake system

(2016) Rebecca J. Clifford et al.   JOURNAL OF CELL SCIENCE

Providing a molecular mechanism for P-glycoprotein; why would I bother?

(2015) R. Callaghan   BIOCHEMICAL SOCIETY TRANSACTIONS

Endothelial β-Catenin Signaling Is Required for Maintaining Adult Blood–Brain Barrier Integrity and Central Nervous System HomeostasisCLINICAL PERSPECTIVE

(2015) Khiem A. Tran et al.   CIRCULATION

Amyloid-β efflux from the central nervous system into the plasma

(2014) Kaleigh Filisa Roberts et al.   ANNALS OF NEUROLOGY

The many “faces” of copper in medicine and treatment

(2014) Anna Hordyjewska et al.   BIOMETALS

Activity of P-Glycoprotein, a  -Amyloid Transporter at the Blood-Brain Barrier, Is Compromised in Patients with Mild Alzheimer Disease

(2014) A. K. Deo et al.   JOURNAL OF NUCLEAR MEDICINE

Differences in amyloid-β clearance across mouse and human blood–brain barrier models: Kinetic analysis and mechanistic modeling

(2014) Hisham Qosa et al.   NEUROPHARMACOLOGY

Inhibition of Wnt/β-catenin signaling downregulates P-glycoprotein and reverses multi-drug resistance of cholangiocarcinoma

(2013) Dong-Yan Shen et al.   CANCER SCIENCE

CNS drug targeting: have we travelled in right path?

(2013) Antony Deva Punitha et al.   JOURNAL OF DRUG TARGETING

Copper promotion of angiogenesis in isolated rat aortic ring: role of vascular endothelial growth factor

(2013) Qi-feng Li et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Role of ABC Transporters in the Pathogenesis of Alzheimer’s Disease

(2012) Alaa H. Abuznait et al.   ACS Chemical Neuroscience

Intracellular trafficking of P-glycoprotein

(2011) Dong Fu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The Alzheimer’s therapeutic PBT2 promotes amyloid-β degradation and GSK3 phosphorylation via a metal chaperone activity

(2011) Peter J. Crouch et al.   JOURNAL OF NEUROCHEMISTRY

Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders

(2011) Berislav V. Zlokovic   NATURE REVIEWS NEUROSCIENCE

Regulation of brain iron and copper homeostasis by brain barrier systems: Implication in neurodegenerative diseases

(2011) Wei Zheng et al.   PHARMACOLOGY & THERAPEUTICS

Alzheimer's Disease

(2011) D. J. Selkoe   Cold Spring Harbor Perspectives in Biology

Wnt/β-catenin signaling controls development of the blood–brain barrier

(2008) Stefan Liebner et al.   JOURNAL OF CELL BIOLOGY

Rapid Restoration of Cognition in Alzheimer's Transgenic Mice with 8-Hydroxy Quinoline Analogs Is Associated with Decreased Interstitial Aβ

(2008) Paul A. Adlard et al.   NEURON

Effects of acute exposure to aluminum on blood–brain barrier and the protection of zinc

(2008) Yang Song et al.   NEUROSCIENCE LETTERS

Modulation of P-Glycoprotein at the Blood-Brain Barrier: Opportunities to Improve Central Nervous System Pharmacotherapy

(2008) D. S. Miller et al.   PHARMACOLOGICAL REVIEWS