Relatively favorable prognosis for MLL -rearranged childhood acute leukemia with reciprocal translocations

The MLL recombinome of acute leukemias in 2017

(2017) C Meyer et al.   LEUKEMIA

Molecular studies reveal MLL-MLLT10/AF10 and ARID5B-MLL gene fusions displaced in a case of infantile acute lymphoblastic leukemia with complex karyotype

(2017) Mitsuteru Hiwatari et al.   Oncology Letters

The AF4-MLL fusion transiently augments multilineage hematopoietic engraftment but is not sufficient to initiate leukemia in cord blood CD34+ cells

(2017) Cristina Prieto et al.   Oncotarget

Acute leukaemia and myelodysplastic syndromes with chromosomal rearrangement involving 11q23 locus, but notMLLgene

(2016) Wenli Zuo et al.   JOURNAL OF CLINICAL PATHOLOGY

Unique FamilialMLL(KMT2A)-Rearranged Precursor B-Cell Infant Acute Lymphoblastic Leukemia in Non-twin Siblings

(2016) Karen A. Urtishak et al.   PEDIATRIC BLOOD & CANCER

Expression of MLL-AF4 or AF4-MLL fusions does not impact the efficiency of DNA damage repair

(2016) Julio Castaño et al.   Oncotarget

Revisiting the biology of infant t(4;11)/MLL-AF4+ B-cell acute lymphoblastic leukemia

(2015) A. Sanjuan-Pla et al.   BLOOD

Treatment outcome of young children with acute lymphoblastic leukaemia: achievements and directions implied from Shanghai Children's Medical Centre based SCMC-ALL-2005 protocol

(2015) Yang Liang et al.   BRITISH JOURNAL OF HAEMATOLOGY

Molecular mechanisms of MLL-associated leukemia

(2015) Akihiko Yokoyama   INTERNATIONAL JOURNAL OF HEMATOLOGY

Clinical usefulness of fluorescencein situhybridization for detection ofMLLrearrangements in acute myeloid leukemia

(2015) Neus Ruiz-Xivillé et al.   LEUKEMIA & LYMPHOMA

Proteasome Inhibitors Evoke Latent Tumor Suppression Programs in Pro-B MLL Leukemias through MLL-AF4

(2014) Han Liu et al.   CANCER CELL

Detection of Gene Rearrangements in Targeted Clinical Next-Generation Sequencing

(2014) Haley J. Abel et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Diverse functions of PHD fingers of the MLL/KMT2 subfamily

(2013) Muzaffar Ali et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The distribution ofMLLbreakpoints correlates with outcome in infant acute leukaemia

(2013) Mariana Emerenciano et al.   BRITISH JOURNAL OF HAEMATOLOGY

The MLL recombinome of acute leukemias in 2013

(2013) C Meyer et al.   LEUKEMIA

Application of next generation sequencing to human gene fusion detection: computational tools, features and perspectives

(2012) Q. Wang et al.   BRIEFINGS IN BIOINFORMATICS

Chromoanagenesis and cancer: mechanisms and consequences of localized, complex chromosomal rearrangements

(2012) Andrew J Holland et al.   NATURE MEDICINE

Genomic analysis of a four-way t(4;11;22;10) associated with MLL-AF4 in an adult acute lymphoblastic leukemia

(2011) Sun Young Cho et al.   ANNALS OF HEMATOLOGY

Three-way Translocation ofMLL/MLLT3, t(1;9;11)(p34.2;p22;q23), in a Pediatric Case of Acute Myeloid Leukemia

(2011) Kyung Ran Jun et al.   Korean Journal of Laboratory Medicine

The PHD3 Domain of MLL Acts as a CYP33-Regulated Switch between MLL-Mediated Activation and Repression,

(2010) Sangho Park et al.   BIOCHEMISTRY

Improved outcome with hematopoietic stem cell transplantation in a poor prognostic subgroup of infants with mixed-lineage-leukemia (MLL)-rearranged acute lymphoblastic leukemia: results from the Interfant-99 Study

(2010) G. Mann et al.   BLOOD

The AF4{middle dot}MLL fusion protein is capable of inducing ALL in mice without requirement of MLL{middle dot}AF4

(2010) A. Bursen et al.   BLOOD

Pro Isomerization in MLL1 PHD3-Bromo Cassette Connects H3K4me Readout to CyP33 and HDAC-Mediated Repression

(2010) Zhanxin Wang et al.   CELL

Genetic aberrations in paediatric acute leukaemias and implications for management of patients

(2010) Tomasz Szczepański et al.   LANCET ONCOLOGY

Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study

(2009) B. V. Balgobind et al.   BLOOD

BreakDancer: an algorithm for high-resolution mapping of genomic structural variation

(2009) Ken Chen et al.   NATURE METHODS