Peroxiredoxin 4 (PRDX4): Its critical in vivo roles in animal models of metabolic syndrome ranging from atherosclerosis to nonalcoholic fatty liver disease

Increased peroxiredoxin 4 levels in patients with prediabetes compared to normal glucose tolerance subjects

(2016) Antoaneta Gateva et al.   CLINICAL ENDOCRINOLOGY

Novel function of histamine signaling via histamine receptors in cholesterol and bile acid metabolism: Histamine H2 receptor protects against nonalcoholic fatty liver disease

(2016) Sohsuke Yamada et al.   PATHOLOGY INTERNATIONAL

Criticalin vivoroles of histamine and histamine receptor signaling in animal models of metabolic syndrome

(2016) Sohsuke Yamada et al.   PATHOLOGY INTERNATIONAL

Overexpression of Peroxiredoxin 4 Affects Intestinal Function in a Dietary Mouse Model of Nonalcoholic Fatty Liver Disease

(2016) Aya Nawata et al.   PLoS One

ERO1: A protein disulfide oxidase and H2O2 producer

(2015) Ester Zito   FREE RADICAL BIOLOGY AND MEDICINE

Physiological and pathological views of peroxiredoxin 4

(2015) Junichi Fujii et al.   FREE RADICAL BIOLOGY AND MEDICINE

Novel function of histamine signaling in hyperlipidemia-induced atherosclerosis: Histamine H1 receptors protect and H2 receptors accelerate atherosclerosis

(2015) Sohsuke Yamada et al.   PATHOLOGY INTERNATIONAL

Histamine receptors expressed in circulating progenitor cells have reciprocal actions in ligation-induced arteriosclerosis

(2015) Sohsuke Yamada et al.   PATHOLOGY INTERNATIONAL

Peroxiredoxin 4 Protects Against Nonalcoholic Steatohepatitis and Type 2 Diabetes in a Nongenetic Mouse Model

(2013) Atsunori Nabeshima et al.   ANTIOXIDANTS & REDOX SIGNALING

Intestinal microbiota in patients with nonalcoholic fatty liver disease

(2013) Marialena Mouzaki et al.   HEPATOLOGY

Synergistic cooperation of PDI family members in peroxiredoxin 4-driven oxidative protein folding

(2013) Yoshimi Sato et al.   Scientific Reports

Apoptosis Signal–Regulating Kinase 1 Deficiency Attenuates Vascular Injury–Induced Neointimal Hyperplasia by Suppressing Apoptosis in Smooth Muscle Cells

(2012) Takashi Tasaki et al.   AMERICAN JOURNAL OF PATHOLOGY

Overexpression of Peroxiredoxin 4 Attenuates Atherosclerosis in Apolipoprotein E Knockout Mice

(2012) Xin Guo et al.   ANTIOXIDANTS & REDOX SIGNALING

Animal Models of Atherosclerosis

(2012) Godfrey S. Getz et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Metformin Prevents and Reverses Inflammation in a Non-Diabetic Mouse Model of Nonalcoholic Steatohepatitis

(2012) Yuki Kita et al.   PLoS One

Smooth Muscle Cell Apoptosis Promotes Vessel Remodeling and Repair via Activation of Cell Migration, Proliferation, and Collagen Synthesis

(2011) Haixiang Yu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Histamine Deficiency Decreases Atherosclerosis and Inflammatory Response in Apolipoprotein E Knockout Mice Independently of Serum Cholesterol Level

(2011) Ke-Yong Wang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Apoptosis Signal–Regulating Kinase 1 Deficiency Accelerates Hyperlipidemia-Induced Atheromatous Plaques via Suppression of Macrophage Apoptosis

(2011) Sohsuke Yamada et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Crystal Structure of Reduced and of Oxidized Peroxiredoxin IV Enzyme Reveals a Stable Oxidized Decamer and a Non-disulfide-bonded Intermediate in the Catalytic Cycle

(2011) Zhenbo Cao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peroxiredoxin Functions as a Peroxidase and a Regulator and Sensor of Local Peroxides

(2011) Sue Goo Rhee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histamine Regulation in Glucose and Lipid Metabolism via Histamine Receptors

(2010) Ke-Yong Wang et al.   AMERICAN JOURNAL OF PATHOLOGY

Overexpression of Peroxiredoxin 4 Protects Against High-Dose Streptozotocin-Induced Diabetes by Suppressing Oxidative Stress and Cytokines in Transgenic Mice

(2010) Yan Ding et al.   ANTIOXIDANTS & REDOX SIGNALING

Peak radial and circumferential strain measured by velocity vector imaging is a novel index for detecting vulnerable plaques in a rabbit model of atherosclerosis

(2010) Lei Zhang et al.   ATHEROSCLEROSIS

Intestinal lipid absorption

(2009) Jahangir Iqbal et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Short-term adaptation of postprandial lipoprotein secretion and intestinal gene expression to a high-fat diet

(2009) Sandra Jimena Hernández Vallejo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Macrophage Apoptosis in Advanced Atherosclerosis

(2009) Ira Tabas et al.   Annals of the New York Academy of Sciences

Apoptosis and Cytokines in Non-Alcoholic Steatohepatitis

(2009) Wing-Kin Syn et al.   Clinics in Liver Disease

Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease

(2009) Luca Miele et al.   HEPATOLOGY

High-fructose diet elevates myocardial superoxide generation in mice in the absence of cardiac hypertrophy

(2009) Kimberley Mellor et al.   NUTRITION

Immunolocalization of 8-OHdG and OGG1 in pancreatic islets of streptozotocin-induced diabetic rats

(2008) Yong Pyong Ku et al.   ACTA HISTOCHEMICA

Matrix Metalloproteinase 12 Accelerates the Initiation of Atherosclerosis and Stimulates the Progression of Fatty Streaks to Fibrous Plaques in Transgenic Rabbits

(2008) Sohsuke Yamada et al.   AMERICAN JOURNAL OF PATHOLOGY

Peroxiredoxin 4knockout results in elevated spermatogenic cell death via oxidative stress

(2008) Yoshihito Iuchi et al.   BIOCHEMICAL JOURNAL

Induction of nuclear factor-κB and its downstream genes by TNF-α and IL-1β has a pro-apoptotic role in pancreatic beta cells

(2008) F. Ortis et al.   DIABETOLOGIA

Mechanisms and consequences of macrophage apoptosis in atherosclerosis

(2008) Tracie Seimon et al.   JOURNAL OF LIPID RESEARCH