The Toxoplasma gondii ME-49 strain upregulates levels of A20 that inhibit NF-κB activation and promotes apoptosis in human leukaemia T-cell lines

Leukocyte Ig-Like receptor B1 restrains dendritic cell function through increased expression of the NF-κB regulator ABIN1/TNIP1

(2016) Rahul C. Khanolkar et al.   JOURNAL OF LEUKOCYTE BIOLOGY

PMA/IONO affects diffuse large B-cell lymphoma cell growth through upregulation of A20 expression

(2016) Wenxiu Yang et al.   ONCOLOGY REPORTS

Is Toxoplasma Gondii Infection a Risk Factor for Leukemia? An Evidence-Based Meta-Analysis

(2016) Yi Huang et al.   MEDICAL SCIENCE MONITOR

MicroRNA let-7 Modulates the Immune Response to Mycobacterium tuberculosis Infection via Control of A20, an Inhibitor of the NF-κB Pathway

(2015) Manish Kumar et al.   Cell Host & Microbe

Toxoplasma gondii isolate with genotype Chinese 1 triggers trophoblast apoptosis through oxidative stress and mitochondrial dysfunction in mice

(2015) Xiucai Xu et al.   EXPERIMENTAL PARASITOLOGY

Increased expressions of ADAMTS-13 and apoptosis contribute to neuropathology duringToxoplasma gondiiencephalitis in mice

(2015) Gungor Cagdas Dincel et al.   NEUROPATHOLOGY

T. gondii rhoptry protein ROP18 induces apoptosis of neural cells via endoplasmic reticulum stress pathway

(2015) Lijuan Wan et al.   Parasites & Vectors

CD8+ T cell immunity in an encephalitis model of Toxoplasma gondii infection

(2015) SuJin Hwang et al.   Seminars in Immunopathology

Toxoplasma gondii induce apoptosis of neural stem cells via endoplasmic reticulum stress pathway

(2014) TENG WANG et al.   PARASITOLOGY

Impairment of T Cell Function in Parasitic Infections

(2014) Vasco Rodrigues et al.   PLoS Neglected Tropical Diseases

MALT1 Small Molecule Inhibitors Specifically Suppress ABC-DLBCL In Vitro and In Vivo

(2012) Lorena Fontan et al.   CANCER CELL

Leishmania donovani Exploits Host Deubiquitinating Enzyme A20, a Negative Regulator of TLR Signaling, To Subvert Host Immune Response

(2012) S. Srivastav et al.   JOURNAL OF IMMUNOLOGY

The Ubiquitin-Editing Protein A20 Prevents Dendritic Cell Activation, Recognition of Apoptotic Cells, and Systemic Autoimmunity

(2011) Mirjam Kool et al.   IMMUNITY

ABIN1 Protein Cooperates with TAX1BP1 and A20 Proteins to Inhibit Antiviral Signaling

(2011) Linlin Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polyubiquitin binding to ABIN1 is required to prevent autoimmunity

(2011) Sambit K. Nanda et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NF-κB in T-cell Acute Lymphoblastic Leukemia: Oncogenic Functions in Leukemic and in Microenvironmental Cells

(2010) Nuno R. dos Santos et al.   Cancers

ABIN-1 negatively regulates NF-κB by inhibiting processing of the p105 precursor

(2009) Shai Cohen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A20 Negatively Regulates T Cell Receptor Signaling to NF- B by Cleaving Malt1 Ubiquitin Chains

(2009) M. Duwel et al.   JOURNAL OF IMMUNOLOGY

Apoptosis in Toxoplasma gondii activated T cells: The role of IFNγ in enhanced alteration of Bcl-2 expression and mitochondrial membrane potential

(2009) Sakhina Begum-Haque et al.   MICROBIAL PATHOGENESIS

ABIN-1 is a ubiquitin sensor that restricts cell death and sustains embryonic development

(2008) Shigeru Oshima et al.   NATURE

T cell antigen receptor stimulation induces MALT1 paracaspase–mediated cleavage of the NF-κB inhibitor A20

(2008) Beatrice Coornaert et al.   NATURE IMMUNOLOGY

The proteolytic activity of the paracaspase MALT1 is key in T cell activation

(2008) Fabien Rebeaud et al.   NATURE IMMUNOLOGY