Article
Endocrinology & Metabolism
Juncai Ye, Qiao Li, Jing Nie
Summary: This study aimed to evaluate the prevalence, characteristics, and associated factors of wrist fractures in Americans aged 50 and above by analyzing data from NHANES. The results showed that the prevalence of wrist fractures among Americans in this age group was 12%.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Review
Medicine, General & Internal
Olawunmi Olagundoye, Janice Y. Kung, William Gibson, Adrian Wagg
Summary: This study aims to conduct a scoping review on UI risk factors in older men in order to provide evidence for the development of evidence-based interventions. The researchers will use JBI's method and protocol to screen and extract relevant studies, and conduct a qualitative and quantitative analysis to describe the risk factors for UI among older men.
Article
Endocrinology & Metabolism
Cecilia Rogmark, Artur Fedorowski, Viktor Hamrefors
Summary: Identification of risk factors associated with incident fractures among middle-aged women and men revealed age, sex, body mass index, previous fracture, family history of fracture, leisure-time physical activity, heavy work, living alone, smoking, and alcohol consumption as significant factors. Individuals with more risk factors had a higher fracture risk, while moderate leisure-time physical activity was associated with lower risk.
JOURNAL OF BONE AND MINERAL RESEARCH
(2021)
Article
Endocrinology & Metabolism
Nicholas C. Harvey, Eric Orwoll, Timothy Kwok, Magnus K. Karlsson, Bjorn E. Rosengren, Eva Ribom, Jane A. Cauley, Peggy M. Cawthon, Kristine Ensrud, Enwu Liu, Alfonso J. Cruz-Jentoft, Roger A. Fielding, Cyrus Cooper, John A. Kanis, Mattias Lorentzon, Claes Ohlsson, Dan Mellstrom, Helena Johansson, Eugene McCloskey
Summary: Adjustment for femoral neck bone mineral density (fnBMD) reduces the predictive value for fracture of sarcopenia definitions based on appendicular lean mass (ALM), but inclusion of physical performance measures strengthens it. Severe sarcopenia definitions incorporating chair stand time, gait speed, and grip strength demonstrate the highest predictability for fracture, even at low prevalence levels.
JOURNAL OF BONE AND MINERAL RESEARCH
(2021)
Article
Endocrinology & Metabolism
W. -Y. Yu, H. -F. Hwang, C. -Y. Chen, M. -R. Lin
Summary: This study found that activity before the fall, type of fall, and falling direction were the main influencing factors of vertebral fractures in older men and women. Risk factors for men included low education, asthma, depression, among others, while for women they included fracture history and osteoporosis. Combining predisposing and situational risk factors can provide a more comprehensive assessment of vertebral fracture risk.
OSTEOPOROSIS INTERNATIONAL
(2021)
Article
Medicine, General & Internal
Wan Fen Yip, Lixia Ge, Bee Hoon Heng, Woan Shin Tan
Summary: This prospective cohort study aimed to identify the risk factors of incident falls between men and women. The findings showed that older age, pre-frailty, and depression or feelings of depression/anxiety were associated with higher odds of incident falls. Subgroup analyses revealed that older age was a risk factor for incident falls in men, while pre-frailty was a risk factor for incident falls in women.
Article
Nutrition & Dietetics
Eva Warensjo Lemming, Liisa Byberg, Jonas Hoijer, Susanna C. Larsson, Alicja Wolk, Karl Michaelsson
Summary: This study in Swedish adults found a non-linear association between dietary calcium intake and hip fracture risk, with adherence to a modified Mediterranean diet leading to reduced hip fracture rates. Both women and men benefitted from a healthy diet in relation to hip fracture risk.
CLINICAL NUTRITION
(2021)
Article
Public, Environmental & Occupational Health
Katsuyasu Kouda, Yuki Fujita, Kumiko Ohara, Takahiro Tachiki, Junko Tamaki, Akiko Yura, Jong-Seong Moon, Etsuko Kajita, Kazuhiro Uenishi, Masayuki Iki
Summary: The trunk-to-peripheral fat ratio is associated with cardiometabolic risk factors independently of whole-body fat mass, particularly in underweight to normal-weight populations. Parameters of the fat ratio may be useful for assessing cardiometabolic risk factors.
ENVIRONMENTAL HEALTH AND PREVENTIVE MEDICINE
(2021)
Article
Cell & Tissue Engineering
N. Walter, D. Szymski, S. M. Kurtz, D. W. Lowenberg, V. Alt, E. Lau, M. Rupp
Summary: This study investigated the incidence and mortality rates of proximal humerus fractures (PHFs) in the elderly population in the USA, as well as the factors influencing mortality rate. The results showed a decrease in incidence rate from 2009 to 2019, although not statistically significant. The one-year mortality rate was higher for nonoperative treatment compared to surgical treatment and shoulder arthroplasty. Significant mortality risk factors after operative treatment included age, sex, COPD, cerebrovascular disease, chronic kidney disease, concomitant fracture, congestive heart failure, and osteoporotic fracture.
BONE & JOINT RESEARCH
(2023)
Article
Medicine, General & Internal
Yanina Balabanova, Bahman Farahmand, Hans Garmo, Par Stattin, Gunnar Brobert
Summary: This nationwide cohort study in Sweden found that men with prostate cancer had a 50% increased risk of venous thromboembolism (VTE) compared with men without prostate cancer during a 5-year follow-up period.
Article
Orthopedics
Kai Song, Bowen Zhu, Yao Yao, Qing Jiang, Jin Xiong, Hongfei Shi
Summary: The study aimed to determine the incidence and independent risk factors of preoperative deep vein thrombosis (DVT) in patients with intertrochanteric fractures. The results showed a high incidence of preoperative DVT and identified factors such as advanced age, female gender, delayed admission, combined cranial trauma, shorter thrombin time, increased level of D-dimer, and lower level of albumin as independent risk factors. It is important to identify high-risk patients for better prevention and treatment of preoperative DVT in this population.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2022)
Article
Peripheral Vascular Disease
Saki Teramura, Kazumasa Yamagishi, Mitsumasa Umesawa, Mina Hayama-Terada, Isao Muraki, Koutatsu Maruyama, Mari Tanaka, Rie Kishida, Tomomi Kihara, Midori Takada, Tetsuya Ohira, Hironori Imano, Yuji Shimizu, Tomoko Sankai, Takeo Okada, Akihiko Kitamura, Masahiko Kiyama, Hiroyasu Iso
Summary: The objective of this study was to examine sex-specific risk factors for hyperuricemia or gout in Japanese cohorts. The results showed that alcohol drinking and hypertension are risk factors for hyperuricemia or gout among men, while smoking is a risk factor among women.
JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS
(2023)
Article
Geriatrics & Gerontology
Donovan T. Maust, Amy S. B. Bohnert, Julie Strominger, Neil Alexander, Lillian Min, Geoffrey J. Hoffman, Jason E. Goldstick
Summary: This study found that older adults prescribed BZD at the lowest dose had a reduced risk of fall injury immediately after taking the medication. Concurrent use of antipsychotics and opioids was also associated with higher short-term fall injury risk.
Article
Geriatrics & Gerontology
Samuel Hawley, Dominic Inman, Celia L. Gregson, Michael Whitehouse, Antony Johansen, Andrew Judge
Summary: This study aims to identify risk factors and examine associations with returning home or recovery of mobility among hip fracture patients who have normal preoperative cognition. The results show that patients with postoperative delirium are less likely to return home or regain outdoor mobility. Multiple factors, including deficits in preoperative cognition and malnutrition, increase the risk of delirium, while the use of preoperative nerve blocks reduces the risk. Understanding the importance of preventing postoperative delirium and identifying high-risk patients can potentially improve outcomes for hip fracture patients.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2023)
Article
Orthopedics
Yunxu Tian, Yanbin Zhu, Kexin Zhang, Miao Tian, Shuhui Qin, Xiuting Li, Yingze Zhang
Summary: The study aimed to determine the incidence and risk factors for postoperative pneumonia in geriatric patients following hip fracture surgeries. The results identified age, sex, respiratory disease, heart disease, cerebrovascular disease, liver disease, preoperative stay, and general anesthesia as independent risk factors for postoperative pneumonia in elderly patients.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2022)
Article
Oncology
Juhua Luo, John T. Schousboe, Kristine E. Ensrud, Michael Hendryx
Summary: Our study aimed to examine long-term cognitive impairment among older breast cancer survivors. We found that breast cancer survivors had accelerated cognitive impairment after cancer diagnosis, especially among women diagnosed at older age or at advanced stage.
JOURNAL OF CANCER SURVIVORSHIP
(2023)
Article
Geriatrics & Gerontology
Mary E. Winger, Paolo Caserotti, Jane A. Cauley, Robert M. Boudreau, Sara R. Piva, Peggy M. Cawthon, Eric S. Orwoll, Kristine E. Ensrud, Deborah M. Kado, Elsa S. Strotmeyer
Summary: This study investigated the application of lower-extremity power and upper-extremity strength in fall injuries and found that lower leg power and grip strength predicted future fall injury risk in older men, independent of physical performance.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Geriatrics & Gerontology
Lisa Langsetmo, John T. Schousboe, Brent C. Taylor, Jane A. Cauley, Howard A. Fink, Peggy M. Cawthon, Marcia L. Stefanick, Deborah M. Kado, Allyson M. Kats, Kristine E. Ensrud
Summary: This study evaluated the risks of clinical fracture, hip fracture, and mortality prior to fracture among men aged at least 80 years. The results showed that fall history, hip bone mineral density, and recent fracture were strong predictors of clinical fracture and hip fracture. Age and multimorbidity were strong predictors of mortality before fracture. The study results have important implications for guiding osteoporosis drug treatment decisions.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Critical Care Medicine
Sobhan Salari Shahrbabaki, Dominik Linz, Susan Redline, Katie Stone, Kristine Ensrud, Mathias Baumert
Summary: Arousal during sleep triggers ventricular repolarization lability, which may increase the risk of long-term cardiovascular mortality. The QT variability index during arousal is independently associated with all-cause and cardiovascular mortality, indicating maladaptation of ventricular repolarization to the arousal stimulus. Further study is needed to determine if arousal suppression can reduce ventricular repolarization lability and subsequent mortality, and if arousal-related QT variability index can be used for more accurate risk stratification.
Article
Geriatrics & Gerontology
Alexandra Cours, Mei-Hua Huang, Howard Fink, Kristine E. Ensrud, John T. Schousboe, Wendy Katzman, Diane Schneider, Nancy E. Lane, Peggy Cawthon, Deborah M. Kado
Summary: This study found that increasing blocks-measured kyphosis is associated with a higher risk of mortality in older men, indicating that hyperkyphosis should be considered as a clinically significant problem.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2023)
Article
Geriatrics & Gerontology
Terri L. Blackwell, Mariana G. Figueiro, Gregory J. Tranah, Jamie M. Zeitzer, Kristine Yaffe, Sonia Ancoli-Israel, Deborah M. Kado, Kristine E. Ensrud, Nancy E. Lane, Yue Leng, Katie L. Stone
Summary: This study found that older men with worse alignment of activity and light had lower levels of cognition and increased rates of cognitive decline. However, there was no association between phasor angle and cognition. Interventions that improve the alignment of light and activity may help slow cognitive decline in older adults.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Medicine, General & Internal
Kenneth Gundle, Elizabeth R. Hooker, Sara E. Golden, Sarah Shull, Kristina Crothers, Anne C. Melzer, Christopher G. Slatore
Summary: The low uptake of lung cancer screening (LCS) is due to the challenges in assessing patients' cigarette pack-years and years since quitting. This study used data from electronic health records to determine LCS eligibility based on age and cigarette use criteria. The results showed high sensitivity but low specificity in identifying former or current tobacco users, indicating the need for more efficient methods of identifying eligible patients. These findings can help healthcare systems improve their LCS outreach efforts and estimate the number of potentially eligible patients.
Article
Medicine, General & Internal
Dana A. Bliuc, Thach Tran, Weiwen Chen, Dunia E. Alarkawi, Dima D. Alajlouni, Fiona R. Blyth, Lyn March, Kristine Ensrud, Robert Blank, Jacqueline Center
Summary: This study investigated the association between multimorbidity and osteoporosis investigation and treatment in fracture patients, and found that multimorbidity significantly impacted the treatment of osteoporosis. This suggests that fracture risk may be underestimated or underprioritized in the presence of other chronic conditions, highlighting the need for improved fracture care in these patients.
Article
Medicine, Research & Experimental
Alan R. Teo, Aaron A. Call, Elizabeth R. Hooker, Clarissa Fong, Elizabeth Karras, Steven K. Dobscha
Summary: The pilot study aimed to determine the feasibility, barriers, and facilitators of a remote trial of VA S.A.V.E. gatekeeper training in close supports of veterans. Despite some challenges, the study found that the remote trial of gatekeeper training is feasible in the specific population.
CONTEMPORARY CLINICAL TRIALS COMMUNICATIONS
(2022)
Article
Emergency Medicine
Kathleen F. Carlson, Tess A. Gilbert, Lauren Maxim, Elizabeth R. Hooker, Sarah Shull, Bryann DeBeer, Susan DeFrancesco, Lauren Denneson
Summary: Suicide is a leading cause of death in the U.S., especially among Veterans. Nonfatal firearm injuries provide important opportunities for suicide prevention, but are currently underutilized. This study analyzed associations between nonfatal firearm injuries and subsequent suicide among Veterans, finding that such injuries may be significant risk factors for suicide.
ACADEMIC EMERGENCY MEDICINE
(2023)
Article
Emergency Medicine
Avery Z. Laliberte, Apoorva Salvi, Elizabeth Hooker, Brandon Roth, Robert Handley, Kathleen Carlson, Denise Hynes, Anais Tuepker, Jason I. Chen
Summary: This study aimed to explore factors associated with the lack of Veterans Health Administration (VHA) care utilization among Veterans with a positive suicide risk screen in the emergency department (ED). The study found that 4.1% of Veterans did not receive VHA mental health services 6 months after the positive screen. Factors associated with not utilizing services included no comorbidity, no mental health diagnosis, no past-year mental health visits, and no past-year homelessness. The findings highlight the need for enhanced follow-up care to mitigate suicide risk among these Veterans.
ACADEMIC EMERGENCY MEDICINE
(2023)
Letter
Critical Care Medicine
Kelly C. Vranas, Elizabeth R. Hooker, Sara E. Golden, Shannon Nugent, Christopher Slatore
Article
Health Care Sciences & Services
Elizabeth R. Hooker, Joaquin Chapa, Kelly C. Vranas, Meike Niederhausen, Sarah J. Goodlin, Christopher G. Slatore, Donald R. Sullivan
Summary: This study aimed to understand the relationship between hospice and palliative care (PC) and factors that influence this relationship. The findings revealed that patients who received PC were more likely to enroll in hospice. Moreover, regional differences and PC team and facility characteristics also affected the use of hospice.
JOURNAL OF PALLIATIVE MEDICINE
(2023)
Letter
Medicine, General & Internal
Carolyn J. Crandall, Kristine E. Ensrud
JAMA INTERNAL MEDICINE
(2023)
Article
Geriatrics & Gerontology
S. R. Bauer, C. E. McCulloch, P. M. Cawthon, K. E. Ensrud, A. M. Suskind, J. C. Newman, S. L. Harrison, A. Senders, K. Covinsky, L. M. Marshall
Summary: Change in phenotypic frailty is associated with non-linear increases in lower urinary tract symptoms (LUTS) severity among older men, independent of age and comorbidities.
JOURNAL OF FRAILTY & AGING
(2023)
