Journal
OSTEOPOROSIS INTERNATIONAL
Volume 29, Issue 5, Pages 1135-1145Publisher
SPRINGER LONDON LTD
DOI: 10.1007/s00198-018-4388-x
Keywords
BMD change; Dietary pattern; Factor analysis; Older men; Prudent; Western
Categories
Funding
- National Institutes of Health (NIH) funding
- NIH Roadmap for Medical Research [U01 AG027810, U01 AG042124, U01 AG042139, U01 AG042140, U01 AG042143, U01 AG042145, U01 AG042168, U01 AR066160, UL1 TR000128, U01 AR45580, U01 AR45614, U01 AR45632, AR45647, AR45654, AR45583, AG18197]
- NIH/NIAMS [P50 AR063043]
- National Institute on Aging (NIA)
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
- National Center for Advancing Translational Sciences (NCATS)
- National Center for Research Resources (NCRR)
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A Summary Studying dietary patterns is often more informative than individual nutrients or foods. We found that a Prudent dietary pattern (rich in vegetables and fish) was associated with reduced loss of total hip BMD in older men. A Prudent dietary pattern may be a potential lifestyle strategy for minimizing bone loss. Introduction This study aimed to identify baseline dietary patterns using factor analysis in a cohort of older men and to evaluate whether the dietary patterns were associated with bone mineral density change (%Delta BMD) at the total hip and femoral neck over time. Methods Participants (n = 4379; mean age 72.9 +/- 5.5 years) were from the Osteoporotic Fractures in Men (MrOS) prospective cohort study and had dietary data collected at baseline (March 2000-April 2002) and BMD measured at baseline and Visit 2 (March 2005-May 2006). Dietary intake was assessed with a brief Block food frequency questionnaire (FFQ); factor analysis was used to derive dietary patterns. BMD was measured by dual-energy x-ray absorptiometry (DXA); %Delta BMD was calculated from baseline to Visit 2. We used generalized linear regression to estimate least square (LS) means of %Delta BMD in quartiles of the dietary pattern scores adjusted for potential confounding factors. Results Two major dietary patterns were derived: Prudent (abundant in vegetables, salad, and non-fried fish) and Western (rich in hamburger, fries, processed meats, cheese, and sweets/desserts). There was an inverse association between adherence to the Prudent pattern and total hip %Delta BMD (p-trend = 0.028 after adjusting for age and clinical site; p-trend = 0.033 after further adjustment for smoking, calcium supplement use, diabetes, hypertension, and total energy intake). No other consistent associations between dietary patterns and %Delta BMD were observed. Conclusions Greater adherence to a Prudent dietary pattern may attenuate total hip BMD loss (%Delta BMD) in older men.
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