Article
Public, Environmental & Occupational Health
Kristin J. Marks, Penelope P. Howards, Melissa M. Smarr, W. Dana Flanders, Kate Northstone, Johnni H. Daniel, Andreas Sjodin, Antonia M. Calafat, Terryl J. Hartman
Summary: The study found that prenatal exposure to mixtures of persistent endocrine-disrupting chemicals may affect birth size, with PFAS being the most important contributors to the association with birth weight.
Article
Environmental Sciences
Bora Plaku-Alakbarova, Oleg Sergeyev, Paige L. Williams, Jane S. Burns, Mary M. Lee, Russ Hauser, Susan A. Korrick
Summary: The study found that in a group of 8-9 year old Russian boys, serum dioxins, furans and PCBs clustered by chlorination pattern, with Sigma NDL-PCBs representing 4,4'-chlorinated PCBs most effectively. This may reflect shared persistence, metabolism or source of exposure of these chemicals in the human body.
Article
Public, Environmental & Occupational Health
Jessica M. Madrigal, Robert M. Sargis, Victoria Persky, Mary E. Turyk
Summary: The study suggests that certain organochlorine pesticides may alter male estradiol levels. The positive associations with estradiol may implicate sex hormones as a possible mechanism for disease risk among those with organochlorine pesticide exposure.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2021)
Article
Environmental Sciences
Saira Amir, Manolis Tzatzarakis, Charalampos Mamoulakis, Jaafar Haris Bello, Syed Ali Musstjab Akber Shah Eqani, Elena Vakonaki, Markos Karavitakis, Sikandar Sultan, Faheem Tahir, Syed Tahir Abbas Shah, Aristidis Tsatsakis
Summary: Male infertility is a major issue with various pathological factors such as endocrine disruption due to environmental pollution. Organochlorine pollutants can disrupt the male reproductive system, with PCBs, DDTs, and HCB being major concerns. Serum samples are the best for assessing health outcomes related to exposure levels.
ENVIRONMENTAL RESEARCH
(2021)
Article
Environmental Sciences
Jaroslav Mosko, Michael Pohorely, Tomas Cajthaml, Michal Jeremias, Ana A. Robles-Aguilar, Siarhei Skoblia, Zdenek Beno, Petra Innemanova, Lucie Linhartova, Klara Michalikova, Erik Meers
Summary: The study focused on using slow pyrolysis to treat organic pollutants in stabilized sewage sludge, finding that temperatures above 600 degrees Celsius effectively removed the majority of organic pollutants. It was proposed that high temperature (>600 degrees Celsius) slow pyrolysis can satisfactorily remove organic pollutants from resulting sludge-char, making it a safe soil improver.
Article
Pediatrics
Maya Berlin, Dana Barchel, Anna Brik, Elkana Kohn, Ayelet Livne, Rimona Keidar, Josef Tovbin, Moshe Betser, Miki Moskovich, Dror Mandel, Ronit Lubetzky, Amit Ovental, Pam Factor-Litvak, Malka Britzi, Tomer Ziv-Baran, Ronit Koren, Chagit Klieger, Matitiahu Berkovitch, Ilan Matok, Ronella Marom
Summary: The study involving 263 mother-newborn dyads found no significant associations between PCB exposure and thyroid function in mothers and newborns. However, in women with low BMI, PCBs may impact TSH and TPO-Ab levels.
FRONTIERS IN PEDIATRICS
(2021)
Article
Environmental Sciences
Rui An, Bin Li, Sining Zhong, Guyu Peng, Jie Li, Ruoqi Ma, Qian Chen, Jinren Ni
Summary: Concerns about groundwater contamination in China have increased due to the growing demand for fresh water and economic development. This study examines the vulnerability of aquifers to hazardous substances in a rapidly urbanizing city, Xiong'an New Area. The researchers collected groundwater samples and identified various emerging organic contaminants (EOCs). They found significant aggregation of EOCs along the Tang River, mainly due to historical residue and accumulation from wastewater storage. The study highlights the importance of controlling groundwater pollution and ensuring drinking water safety in rapidly urbanizing cities.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Pediatrics
Anna A. Kroenke, Anne Jurkutat, Maike Schlingmann, Tanja Poulain, Matthias Nuechter, Anja Hilbert, Hannu Kiviranta, Antje Koerner, Mandy Vogel, Olle Soeder, Carl G. Bornehag, Wieland Kiess
Summary: The study found that maternal exposure to persistent organic pollutants (POPs) affects various aspects of pre- and postnatal development, as well as the thyroid hormone status of both mother and child. Pregnant women in a German cohort showed significant accumulation of POPs, with correlations between maternal POP levels and child's birth length and weight gain, as well as FT3 levels in the mother and child. These findings provide additional evidence for the potentially harmful influence of POPs on maternal and child health.
PEDIATRIC RESEARCH
(2022)
Article
Endocrinology & Metabolism
Guelen Ayhan, Florence Rouget, Frank Giton, Nathalie Costet, Leah Michineau, Christine Monfort, Jean-Pierre Thome, Philippe Kadhel, Sylvaine Cordier, Alejandro Oliva, Luc Multigner
Summary: In utero exposure to chlordecone was associated with elevated levels of selected thyroid (TSH) and sex-steroid (DHEA, TT, and DHT) hormones at seven years in a non-monotonic dose response (inverted U) relationship, suggesting potential implications for future health and reproductive function in adolescence and adulthood.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Environmental Sciences
Kristin J. Marks, Penelope P. Howards, Melissa M. Smarr, W. Dana Flanders, Kate Northstone, Johnni H. Daniel, Antonia M. Calafat, Andreas Sjodin, Michele Marcus, Terryl J. Hartman
Summary: The study found that prenatal exposure to mixtures of persistent EDCs is not significantly associated with early menarche in female offspring.
ENVIRONMENTAL POLLUTION
(2021)
Article
Endocrinology & Metabolism
Edwina Brennan, Alexandra E. Butler, Daniel S. Drage, Thozhukat Sathyapalan, Stephen L. Atkin
Summary: This study found a correlation between PCBs and certain circulating miRNAs, but not with metabolic parameters. In the healthy control group, these miRNAs were associated with menstrual cycle factors, while the correlation was weaker in the PCOS group. This suggests that PCBs may affect fertility through their impact on the hypothalamo-ovarian axis.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Environmental Sciences
Shanshan Xu, Solrunn Hansen, Arja Rautio, Marjo-Riitta Jarvelin, Khaled Abass, Jaana Rysa, Saranya Palaniswamy, Sandra Huber, Joan O. Grimalt, Pierre Dumas, Jon Oyvind Odland
Summary: This study found lower levels of selected persistent organic pollutants (POPs) in the serum of women from Northern Norway, with concentrations of dioxins, polychlorinated biphenyls (PCBs), organochlorine pesticides (OCPs), and chlorinated paraffins showing decreasing trends over the studied period. However, medium chain chlorinated paraffins exhibited an increasing trend, raising concerns about their emerging contamination impact on humans. Further global observational studies with larger sample sizes on chlorinated paraffins are needed to validate these findings.
ENVIRONMENTAL RESEARCH
(2022)
Review
Oncology
Tammy C. Bleak, Gloria M. Calaf
Summary: Environmental endocrine disruptor chemicals can disrupt the endocrine system in living organisms, leading to hormone-related cancers. It is crucial to study the susceptibility of organs to these substances.
Article
Environmental Sciences
Yanfen Hao, Yingming Li, Frank Wania, Ruiqiang Yang, Pu Wang, Qinghua Zhang, Guibin Jiang
Summary: Passive air samples were collected in Ny-Alesund and London Island in the Arctic annually for seven years to investigate concentrations of persistent organic pollutants (POPs). The study found declining trends in most POPs, with 3,3'-dichlorobiphenyl (PCB-11) being prevalent. Long-range atmospheric transport was identified as the main factor influencing the distribution of POPs in the Arctic atmosphere, with minor impact from human activities at research stations.
Article
Environmental Sciences
Mingye Zhang, Limei Wang, Xiang Li, Lulu Song, Dan Luo, Qiang Li, Youjie Wang, Zhengce Wan, Surong Mei
Summary: This study investigated the association between individual and combined exposure to PCBs and OCPs and the risk of metabolic syndrome (MetS) in Wuhan, China. The results showed that PCBs and OCPs were commonly detected in the samples and were positively correlated with increased odds of MetS. Furthermore, the mixture of PCBs and OCPs, with p,p'-DDE being the largest contributor, was also associated with the risk of MetS.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Clemence Vannier, Cecile Chevrier, Laurence Hubert-Moy
Summary: This review analyzes the role of Land Use and Land Cover (LULC) in Residential Exposure to Agricultural Pesticides (REAP) and highlights the need for further research on LULC mitigation elements.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH
(2022)
Article
Chemistry, Analytical
Jade Chaker, David Mobjerg Kristensen, Thorhallur Ingi Halldorsson, Sjurdur Frodi Olsen, Christine Monfort, Cecile Chevrier, Bernard Jegou, Arthur David
Summary: Sample preparation methods have a significant impact on the detection of low-abundant chemicals in biological samples. This study evaluated the performance of 12 sample preparation methods and proposed a combination of protein precipitation and phospholipid and protein removal plates to broaden the visible chemical space.
ANALYTICAL CHEMISTRY
(2022)
Article
Environmental Sciences
Abir Aachimi, Florian Marc, Nathalie Bonvallot, Frederic Clerc
Summary: A work situation matrix constructed from French data can help occupational safety and health managers determine the level of risks for work tasks and prioritize those that are most risky.
JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HYGIENE
(2022)
Article
Public, Environmental & Occupational Health
Parisa Montazeri, Serena Fossati, Charline Warembourg, Maribel Casas, Diana B. P. Clemente, Raquel Garcia-Esteban, Tim S. Nawrot, Martine Vrijheid
Summary: This study aimed to evaluate the association between prenatal exposure to phthalates and phenols and macro- and microvascular health during early adolescence. The results showed little evidence to suggest that prenatal exposure to these chemicals is associated with cardiovascular health, except for a few associations with certain compounds.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2022)
Article
Environmental Sciences
Z. Chupeau, F. Mercier, E. Rouxel, B. Le Bot, G. Chauvet, T. Simeon, N. Bonvallot, C. Zaros, C. Chevrier, P. Glorennec
Summary: This study describes the pre- and post-natal exposure of children to organophosphate flame retardants (OPFRs) and explores their possible determinants. The results show correlations between pre- and post-natal exposures, but no correlations between different OPFRs. Additionally, pre-natal exposure is associated with exposure to polybrominated diphenyl ethers, and home renovation work and the type of flooring in children's rooms are also associated with exposure. Higher socioeconomic status is associated with lower exposure to certain OPFRs.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Environmental Sciences
Paula de Prado-Bert, Charline Warembourg, Audrius Dedele, Barbara Heude, Eva Borras, Eduard Sabido, Gunn Marit Aasvang, Johanna Lepeule, John Wright, Jose Urquiza, Kristine B. Gutzkow, Lea Maitre, Leda Chatzi, Maribel Casas, Marina Vafeiadi, Mark J. Nieuwenhuijsen, Montserrat de Castro, Regina Grazuleviciene, Rosemary R. C. McEachan, Xavier Basagana, Martine Vrijheid, Jordi Sunyer, Mariona Bustamante
Summary: This study explored the association between air pollution exposure and protein profiles, as well as their link with blood pressure in children. The findings suggest that certain air pollutants are positively associated with the levels of hepatocyte growth factor (HGF) and interleukin 8 (IL8), and home exposure to NO2 is related to higher systolic blood pressure.
ENVIRONMENTAL RESEARCH
(2022)
Review
Urology & Nephrology
Jacques Auger, Florence Eustache, Cecile Chevrier, Bernard Jegou
Summary: Studies over the past four decades have shown geographical differences in sperm production and suggest a possible decline over time. However, the evidence is not clear on whether human semen quality is deteriorating worldwide or in the Western world.
NATURE REVIEWS UROLOGY
(2022)
Article
Environmental Sciences
Nuria Guil-Oumrait, German Cano-Sancho, Parisa Montazeri, Nikos Stratakis, Charline Warembourg, Maria-Jose Lopez-Espinosa, Jesus Vioque, Loreto Santa-Marina, Alba Jimeno-Romero, Rosa Ventura, Nuria Monfort, Martine Vrijheid, Maribel Casas
Summary: This study aimed to assess the effects of prenatal exposure to phthalates and phenols on childhood BMI and blood pressure. The results showed that benzophenone-3 (BP3) may be associated with higher BMI and diastolic blood pressure, while methyl paraben (MEPA) may be associated with lower systolic blood pressure. However, there was little evidence for an overall effect of the chemical mixture.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Environmental Sciences
Lea Maitre, Jean-Baptiste Guimbaud, Charline Warembourg, Nuria Guil-Oumrait, Paula Marcela Petrone, Marc Chadeau-Hyam, Martine Vrijheid, Xavier Basagana, Juan R. Gonzalez
Summary: The exposome recognizes the simultaneous exposure of individuals to various environmental factors and aims to discover the factors behind diseases using a holistic approach. However, quantifying the health effects of complex exposure mixtures presents challenges. To address these challenges, the Barcelona Institute for Global Health organized a data challenge event where researchers from different disciplines could compete and apply state-of-the-art methods on a partially simulated exposome dataset.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Environmental Sciences
Mathilde Lize, Christine Monfort, Florence Rouget, Gwendolina Limon, Gael Durand, Helene Tillaut, Cecile Chevrier
Summary: This study found that prenatal exposure to certain organophosphate pesticides was associated with increased autistic traits in 11-year-old children. Specifically, maternal urine samples with detectable levels of chlorpyrifos or its metabolites were significantly associated with higher scores on autism spectrum trait assessments.
ENVIRONMENTAL RESEARCH
(2022)
Article
Public, Environmental & Occupational Health
Ian Hough, Matthieu Rolland, Ariane Guilbert, Emie Seyve, Barbara Heude, Remy Slama, Sarah Lyon-Caen, Isabelle Pin, Cecile Chevrier, Itai Kloog, Johanna Lepeule
Summary: This study aimed to evaluate the association between ambient temperature and preterm delivery. The results showed that night-time heat and cold exposure were associated with an increased risk of preterm birth in a temperate climate.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Environmental Sciences
M. Kadawathagedara, G. Muckle, S. Cordier, L. Michineau, B. Tressieres, A. Mallard, L. Kovacic, L. Multigner, P. Quenel, C. Chevrier
Summary: This study found that prenatal exposure to Zika virus and household insecticides may have adverse effects on the health, development, and behavior of newborns. The results showed that these exposures were associated with smaller head circumference and lower birth weight among newborns, and also affected development and behavior at 18 months of age.
ENVIRONMENTAL RESEARCH
(2022)
Article
Environmental Sciences
Natacha Tessier, Romain Boissonnot, Virginie Desvignes, Marie Frochen, Mathilde Merlo, Olivier Blanchard, Cecile Chevrier, Laurence Guldner, Corinne Mandin, Ohri Yamada, Jean-Luc Volatier
Summary: This study investigated pesticide usage in French households and compiled a list of pesticides and active ingredients stored at home. The findings showed that 75% of households had used at least one pesticide in the past year, with insecticides, particularly pyrethroids, being the most commonly used type.
ENVIRONMENTAL RESEARCH
(2023)
Article
Environmental Sciences
Naomi Lejeune, Fabien Mercier, Cecile Chevrier, Nathalie Bonvallot, Barbara Le Bot
Summary: This study aimed to assess the exposure of pregnant women in Brittany to pesticides, and results show the detection of organophosphate and pyrethroid residues, providing valuable insights into the exposure situation.
JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY
(2022)
Article
Endocrinology & Metabolism
Helene Tillaut, Christine Monfort, Frank Giton, Charline Warembourg, Florence Rouget, Sylvaine Cordier, Fabrice Laine, Eric Gaudreau, Ronan Garlantezec, Dave Saint-Amour, Cecile Chevrier
Summary: This cross-sectional study highlights associations between some persistent organic pollutants (POPs) and thyroid function disruption, which is consistent with the existing literature. The associations were found to be sex-specific and moderated by pubertal status in boys, suggesting the involvement of complex endocrine interactions.
NEUROENDOCRINOLOGY
(2022)