4.8 Article

Iron-Catalyzed Aerobic Oxidation and Annulation Reaction of Pyridine and α-Substituted Allenoate toward Functionalized Indolizine

Journal

ORGANIC LETTERS
Volume 20, Issue 2, Pages 413-416

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.7b03696

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Funding

  1. National Natural Science Foundation of China [21472121, 21272148]
  2. State Key Laboratory of Applied Organic Chemistry, Lanzhou University

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An iron-catalyzed reaction of pyridine and a substituted allenoate has been disclosed. The present strategy incorporates the aerobic oxidation into annulation involving substituted allenoate, thus providing a new access to functionalized indolizine.

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