Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 16, Issue 25, Pages 4628-4632Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8ob00989a
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Funding
- National Natural Science Foundation of China [21472172, 21272212]
- Natural Science Foundation of Zhejiang Province [LY17B060009]
- Zhejiang University Student Science and Technology Innovation Program [2017R403052]
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In this study, a single fluorescent probe (DPFP) containing a 1,8-naphthalimide dye and a homoallylamino group for imaging pH and formaldehyde (FA) has been developed that exhibits significant blue fluorescence ((em) at 455 nm) under acidic pH conditions (pH < 7.0) and green fluorescence ((em) at 555 nm) in the presence of FA, respectively. Furthermore, probe DPFP was successfully applied to image acidic lysosomes and exogenous or endogenous FA in living HeLa cells.
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