Human recombinant arginase enzyme reduces plasma arginine in mouse models of arginase deficiency

Arginine deprivation in cancer therapy

(2015) Lynn G. Feun et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Treatment of arginase deficiency revisited: guanidinoacetate as a therapeutic target and biomarker for therapeutic monitoring

(2014) Wajdi Amayreh et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Myocyte-mediated Arginase Expression Controls Hyperargininemia but not Hyperammonemia in Arginase-deficient Mice

(2014) Chuhong Hu et al.   MOLECULAR THERAPY

Recombinant Human Arginase Toxicity in Mice Is Reduced by Citrulline Supplementation

(2014) Jeremy P. Mauldin et al.   Translational Oncology

Lethal phenotype in conditional late-onset arginase 1 deficiency in the mouse

(2013) Jennifer Kasten et al.   MOLECULAR GENETICS AND METABOLISM

Inducible Arginase 1 Deficiency in Mice Leads to Hyperargininemia and Altered Amino Acid Metabolism

(2013) Yuan Yan Sin et al.   PLoS One

Argocytes Containing Enzyme Nanoparticles Reduce Toxic Concentrations of Arginine in the Blood

(2012) Yu. G. Kaminsky et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

Clinical Features and Neurologic Progression of Hyperargininemia

(2012) Daniel R. Carvalho et al.   PEDIATRIC NEUROLOGY

Retinal risks of high-dose ornithine supplements: a review

(2011) Seiji Hayasaka et al.   BRITISH JOURNAL OF NUTRITION

Strategies for optimizing the serum persistence of engineered human arginase I for cancer therapy

(2011) Everett Stone et al.   JOURNAL OF CONTROLLED RELEASE

Replacing Mn2+with Co2+in Human Arginase I Enhances Cytotoxicity towardl-Arginine Auxotrophic Cancer Cell Lines

(2010) Everett M. Stone et al.   ACS Chemical Biology

Arginase deficiency in multiple tissues in argininemia

(2010) Virginia V. Michels et al.   CLINICAL GENETICS

Guanidino compound levels in blood, cerebrospinal fluid, and post-mortem brain material of patients with argininemia

(2010) Joshua L. Deignan et al.   MOLECULAR GENETICS AND METABOLISM

Establishing a consortium for the study of rare diseases: The Urea Cycle Disorders Consortium

(2010) Jennifer Seminara et al.   MOLECULAR GENETICS AND METABOLISM

Toll-like receptor–induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

(2008) Karim C El Kasmi et al.   NATURE IMMUNOLOGY

Increased plasma and tissue guanidino compounds in a mouse model of hyperargininemia

(2007) Joshua L. Deignan et al.   MOLECULAR GENETICS AND METABOLISM