Integrative pathway genomics of lung function and airflow obstruction

Genome-wide association analysis identifies six new loci associated with forced vital capacity

(2014) Daan W Loth et al.   NATURE GENETICS

Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis

(2014) Michael H Cho et al.   Lancet Respiratory Medicine

Gene set bagging for estimating the probability a statistically significant result will replicate

(2013) Andrew E Jaffe et al.   BMC BIOINFORMATICS

Systematic identification of trans eQTLs as putative drivers of known disease associations

(2013) Harm-Jan Westra et al.   NATURE GENETICS

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

(2013) Danielle Welter et al.   NUCLEIC ACIDS RESEARCH

Genome-Wide Association Studies IdentifyCHRNA5/3andHTR4in the Development of Airflow Obstruction

(2012) Jemma B. Wilk et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

BEDOPS: high-performance genomic feature operations

(2012) Shane Neph et al.   BIOINFORMATICS

Extracellular matrix composition in COPD

(2012) Raquel Annoni et al.   EUROPEAN RESPIRATORY JOURNAL

Systematic Localization of Common Disease-Associated Variation in Regulatory DNA

(2012) M. T. Maurano et al.   SCIENCE

Ten Years of Pathway Analysis: Current Approaches and Outstanding Challenges

(2012) Purvesh Khatri et al.   PLoS Computational Biology

Lung eQTLs to Help Reveal the Molecular Underpinnings of Asthma

(2012) Ke Hao et al.   PLoS Genetics

Genome-Wide Joint Meta-Analysis of SNP and SNP-by-Smoking Interaction Identifies Novel Loci for Pulmonary Function

(2012) Dana B. Hancock et al.   PLoS Genetics

Acute Exacerbations of Chronic Obstructive Pulmonary Disease

(2011) Mona Bafadhel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Interactome Networks and Human Disease

(2011) Marc Vidal et al.   CELL

Matrix metalloproteinases in COPD

(2011) A. Churg et al.   EUROPEAN RESPIRATORY JOURNAL

The future of chronic obstructive pulmonary disease treatment—difficulties of and barriers to drug development

(2011) Fernando J Martinez et al.   LANCET

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function

(2011) María Soler Artigas et al.   NATURE GENETICS

Differential Expression of Tissue Repair Genes in the Pathogenesis of Chronic Obstructive Pulmonary Disease

(2010) John V. Gosselink et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Targeting Phosphoinositide-3-Kinase-δ with Theophylline Reverses Corticosteroid Insensitivity in Chronic Obstructive Pulmonary Disease

(2010) Yasuo To et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

Meta-analysis of gene-environment interaction: joint estimation of SNP and SNP × environment regression coefficients

(2010) Alisa K. Manning et al.   GENETIC EPIDEMIOLOGY

Analysing biological pathways in genome-wide association studies

(2010) Kai Wang et al.   NATURE REVIEWS GENETICS

GSA-SNP: a general approach for gene set analysis of polymorphisms

(2010) Dougu Nam et al.   NUCLEIC ACIDS RESEARCH

i-GSEA4GWAS: a web server for identification of pathways/gene sets associated with traits by applying an improved gene set enrichment analysis to genome-wide association study

(2010) K. Zhang et al.   NUCLEIC ACIDS RESEARCH

Diverse Genome-wide Association Studies Associate the IL12/IL23 Pathway with Crohn Disease

(2009) Kai Wang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genome-wide Association Analysis Identifies PDE4D as an Asthma-Susceptibility Gene

(2009) Blanca E. Himes et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Allergic airway hyperresponsiveness, inflammation, and remodeling do not develop in phosphoinositide 3-kinase γ–deficient mice

(2009) Masahide Takeda et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Assessment of air space size characteristics by intercept (chord) measurement: an accurate and efficient stereological approach

(2009) Lars Knudsen et al.   JOURNAL OF APPLIED PHYSIOLOGY

Molecular networks as sensors and drivers of common human diseases

(2009) Eric E. Schadt   NATURE

Genome-wide association study identifies five loci associated with lung function

(2009) Emmanouela Repapi et al.   NATURE GENETICS

Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function

(2009) Dana B Hancock et al.   NATURE GENETICS

MMP12,Lung Function, and COPD in High-Risk Populations

(2009) Gary M. Hunninghake et al.   NEW ENGLAND JOURNAL OF MEDICINE

Common Regulatory Variation Impacts Gene Expression in a Cell Type-Dependent Manner

(2009) A. S. Dimas et al.   SCIENCE

A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci

(2009) Sreekumar G. Pillai et al.   PLoS Genetics

Genome-Wide Association Study Implicates Chromosome 9q21.31 as a Susceptibility Locus for Asthma in Mexican Children

(2009) Dana B. Hancock et al.   PLoS Genetics

Genome-wide association study identifies ANXA11 as a new susceptibility locus for sarcoidosis

(2008) Sylvia Hofmann et al.   NATURE GENETICS

Using the lower limit of normal for the FEV1/FVC ratio reduces the misclassification of airway obstruction

(2008) M P Swanney et al.   THORAX

Distinct Roles for Arp2/3 Regulators in Actin Assembly and Endocytosis

(2007) Brian J Galletta et al.   PLOS BIOLOGY