TBX1 protein interactions and microRNA-96-5p regulation controls cell proliferation during craniofacial and dental development: implications for 22q11.2 deletion syndrome

Tbx1 is required autonomously for cell survival and fate in the pharyngeal core mesoderm to form the muscles of mastication

(2014) Ping Kong et al.   HUMAN MOLECULAR GENETICS

A Pituitary Homeobox 2 (Pitx2):microRNA-200a-3p:β-catenin Pathway Converts Mesenchymal Cells to Amelogenin-expressing Dental Epithelial Cells

(2014) Thad Sharp et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian TBX1 Preferentially Binds and Regulates Downstream Targets Via a Tandem T-site Repeat

(2014) Raquel Castellanos et al.   PLoS One

The Pitx2:miR-200c/141:noggin pathway regulates Bmp signaling and ameloblast differentiation

(2013) H. Cao et al.   DEVELOPMENT

MicroRNA-17-92, a Direct Ap-2α Transcriptional Target, Modulates T-Box Factor Activity in Orofacial Clefting

(2013) Jun Wang et al.   PLoS Genetics

Sox2+ Stem Cells Contribute to All Epithelial Lineages of the Tooth via Sfrp5+ Progenitors

(2012) Emma Juuri et al.   DEVELOPMENTAL CELL

Tbx1 regulates oral epithelial adhesion and palatal development

(2012) Noriko Funato et al.   HUMAN MOLECULAR GENETICS

An RNA interference screen uncovers a new molecule in stem cell self-renewal and long-term regeneration

(2012) Ting Chen et al.   NATURE

Pharyngeal mesoderm regulatory network controls cardiac and head muscle morphogenesis

(2012) I. Harel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dental developmental disturbances in 50 individuals with the 22q11.2 deletion syndrome; relation to medical conditions?

(2011) Hilde Nordgarden et al.   ACTA ODONTOLOGICA SCANDINAVICA

Head and neck manifestations of 22q11.2 deletion syndromes

(2011) Tal Marom et al.   EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY

Hierarchical Interactions of Homeodomain and Forkhead Transcription Factors in Regulating Odontogenic Gene Expression

(2011) Shankar R. Venugopalan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of MicroRNAs in the Stem Cell Niche of the Adult Mouse Incisor

(2011) Andrew H. Jheon et al.   PLoS One

Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs

(2010) Frederic Michon et al.   DEVELOPMENTAL BIOLOGY

Tbx1 regulates progenitor cell proliferation in the dental epithelium by modulating Pitx2 activation of p21

(2010) Huojun Cao et al.   DEVELOPMENTAL BIOLOGY

Bmp Signaling Regulates Myocardial Differentiation from Cardiac Progenitors Through a MicroRNA-Mediated Mechanism

(2010) Jun Wang et al.   DEVELOPMENTAL CELL

MicroRNAs Regulate Pituitary Development, and MicroRNA 26b Specifically Targets Lymphoid Enhancer Factor 1 (Lef-1), Which Modulates Pituitary Transcription Factor 1 (Pit-1) Expression

(2010) Zichao Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNAs Play a Critical Role in Tooth Development

(2010) H. Cao et al.   JOURNAL OF DENTAL RESEARCH

Tbx1 is necessary for palatal elongation and elevation

(2010) Steven Goudy et al.   MECHANISMS OF DEVELOPMENT

Tbx1 Regulates Proliferation and Differentiation of Multipotent Heart Progenitors

(2009) Li Chen et al.   CIRCULATION RESEARCH

Enamel-free teeth: Tbx1 deletion affects amelogenesis in rodent incisors

(2009) Javier Catón et al.   DEVELOPMENTAL BIOLOGY

Gain of function ofTbx1affects pharyngeal and heart development in the mouse

(2009) Francesca Vitelli et al.   GENESIS

Epithelial Fibroblast Growth Factor Receptor 1 Regulates Enamel Formation

(2009) K. Takamori et al.   JOURNAL OF DENTAL RESEARCH

Mutations in the seed region of human miR-96 are responsible for nonsyndromic progressive hearing loss

(2009) Ángeles Mencía et al.   NATURE GENETICS

Tbx1 Regulates the BMP-Smad1 Pathway in a Transcription Independent Manner

(2009) F. Gabriella Fulcoli et al.   PLoS One

MicroRNA expression profiling of the developing murine molar tooth germ and the developing murine submandibular salivary gland

(2008) Anne-Marthe Jevnaker et al.   ARCHIVES OF ORAL BIOLOGY

Human and Mouse Enamel Phenotypes Resulting from Mutation or Altered Expression of AMEL, ENAM, MMP20 and KLK4

(2008) J. Timothy Wright et al.   CELLS TISSUES ORGANS

A regulatory relationship between Tbx1 and FGF signaling during tooth morphogenesis and ameloblast lineage determination

(2008) Thimios A. Mitsiadis et al.   DEVELOPMENTAL BIOLOGY

Deletion of the Pitx1 genomic locus affects mandibular tooth morphogenesis and expression of the Barx1 and Tbx1 genes

(2007) Thimios A. Mitsiadis et al.   DEVELOPMENTAL BIOLOGY