Candidate genetic modifiers of retinitis pigmentosa identified by exploiting natural variation inDrosophila

Natural Variation in Gene Expression Modulates the Severity of Mutant Phenotypes

(2015) Victoria Vu et al.   CELL

MAP4K4 regulates integrin-FERM binding to control endothelial cell motility

(2015) Philip Vitorino et al.   NATURE

A New Initiative on Precision Medicine

(2015) Francis S. Collins et al.   NEW ENGLAND JOURNAL OF MEDICINE

Behavioral idiosyncrasy reveals genetic control of phenotypic variability

(2015) Julien F. Ayroles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exome Sequence Analysis Suggests that Genetic Burden Contributes to Phenotypic Variability and Complex Neuropathy

(2015) Claudia Gonzaga-Jauregui et al.   Cell Reports

Linkage Disequilibrium and Inversion-Typing of the Drosophila melanogaster Genome Reference Panel

(2015) David Houle et al.   G3-Genes Genomes Genetics

A Genome-Wide Association Study for Nutritional Indices in Drosophila

(2015) Robert L. Unckless et al.   G3-Genes Genomes Genetics

Global Diversity Lines–A Five-Continent Reference Panel of Sequenced Drosophila melanogaster Strains

(2015) Jennifer K. Grenier et al.   G3-Genes Genomes Genetics

Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines

(2014) W. Huang et al.   GENOME RESEARCH

GPR179 Is Required for High Sensitivity of the mGluR6 Signaling Cascade in Depolarizing Bipolar Cells

(2014) T. A. Ray et al.   JOURNAL OF NEUROSCIENCE

Cryptic genetic variation: evolution's hidden substrate

(2014) Annalise B. Paaby et al.   NATURE REVIEWS GENETICS

Melanoma susceptibility as a complex trait: genetic variation controls all stages of tumor progression

(2014) B Ferguson et al.   ONCOGENE

Mutations in Four Glycosyl Hydrolases Reveal a Highly Coordinated Pathway for Rhodopsin Biosynthesis and N-Glycan Trimming in Drosophila melanogaster

(2014) Erica E. Rosenbaum et al.   PLoS Genetics

Potential roles of adenosine deaminase-2 in diabetic retinopathy

(2013) Nehal M. Elsherbiny et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Genetic architecture of quantitative traits and complex diseases

(2013) Wenqing Fu et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Effect of Genetic Variation in a Drosophila Model of Diabetes-Associated Misfolded Human Proinsulin

(2013) B. Z. He et al.   GENETICS

Genetic Complexity in a Drosophila Model of Diabetes-Associated Misfolded Human Proinsulin

(2013) S.-Y. Park et al.   GENETICS

The Collaborative Cross: A Recombinant Inbred Mouse Population for the Systems Genetic Era

(2013) D. W. Threadgill et al.   ILAR JOURNAL

Using natural variation in Drosophila to discover previously unknown endoplasmic reticulum stress genes

(2013) C. Y. Chow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GPR179 Is Required for Depolarizing Bipolar Cell Function and Is Mutated in Autosomal-Recessive Complete Congenital Stationary Night Blindness

(2012) Neal S. Peachey et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Whole-Exome Sequencing Identifies Mutations in GPR179 Leading to Autosomal-Recessive Complete Congenital Stationary Night Blindness

(2012) Isabelle Audo et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Large Neurological Component to Genetic Differences Underlying Biased Sperm Use in Drosophila

(2012) C. Y. Chow et al.   GENETICS

A broad expression profile of the GMR-GAL4 driver in Drosophila melanogaster

(2012) W.-Z. Li et al.   GENETICS AND MOLECULAR RESEARCH

The diversity outbred mouse population

(2012) Gary A. Churchill et al.   MAMMALIAN GENOME

The Drosophila melanogaster Genetic Reference Panel

(2012) Trudy F. C. Mackay et al.   NATURE

CDK5 and MEKK1 mediate pro-apoptotic signalling following endoplasmic reticulum stress in an autosomal dominant retinitis pigmentosa model

(2012) Min-Ji Kang et al.   NATURE CELL BIOLOGY

Genome-wide efficient mixed-model analysis for association studies

(2012) Xiang Zhou et al.   NATURE GENETICS

Knockdown of Bardet-Biedl Syndrome Gene BBS9/PTHB1 Leads to Cilia Defects

(2012) Shobi Veleri et al.   PLoS One

Genome-Wide Association for Sensitivity to Chronic Oxidative Stress in Drosophila melanogaster

(2012) Katherine W. Jordan et al.   PLoS One

Genome-Wide Association Analysis of Oxidative Stress Resistance in Drosophila melanogaster

(2012) Allison L. Weber et al.   PLoS One

Association of Shank 1A Scaffolding Protein with Cone Photoreceptor Terminals in the Mammalian Retina

(2012) Salvatore L. Stella et al.   PLoS One

Modifier Genes and the Plasticity of Genetic Networks in Mice

(2012) Bruce A. Hamilton et al.   PLoS Genetics

The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function

(2010) David Warde-Farley et al.   NUCLEIC ACIDS RESEARCH

ER stress protects from retinal degeneration

(2009) César S Mendes et al.   EMBO JOURNAL

Mechanistic insights into Bardet-Biedl syndrome, a model ciliopathy

(2009) Norann A. Zaghloul et al.   JOURNAL OF CLINICAL INVESTIGATION

Decanalization and the origin of complex disease

(2009) Greg Gibson   NATURE REVIEWS GENETICS

Overexpression of Myocilin in the Drosophila Eye Activates the Unfolded Protein Response: Implications for Glaucoma

(2009) Mary Anna Carbone et al.   PLoS One

Suppression of retinal degeneration in Drosophila by stimulation of ER-associated degradation

(2009) M.-J. Kang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Inflammatory Response to Cell Death

(2008) Kenneth L. Rock et al.   Annual Review of Pathology-Mechanisms of Disease