IRF4, MC1R and TYR genes are risk factors for actinic keratosis independent of skin color

A Polymorphism in IRF4 Affects Human Pigmentation through a Tyrosinase-Dependent MITF/TFAP2A Pathway

(2013) Christian Praetorius et al.   CELL

The Rotterdam Study: 2014 objectives and design update

(2013) Albert Hofman et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans

(2013) Mingfeng Zhang et al.   HUMAN MOLECULAR GENETICS

Prevalence of Actinic Keratosis and Its Risk Factors in the General Population: The Rotterdam Study

(2013) Sophie C. Flohil et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

(2013) Joshua C Denny et al.   NATURE BIOTECHNOLOGY

Discovery and refinement of loci associated with lipid levels

(2013) Cristen J Willer et al.   NATURE GENETICS

Comprehensive candidate gene study highlights UGT1A and BNC2 as new genes determining continuous skin color variation in Europeans

(2012) Leonie C. Jacobs et al.   HUMAN GENETICS

MC1R Variant Allele Effects on UVR-Induced Phosphorylation of p38, p53, and DDB2 Repair Protein Responses in Melanocytic Cells in Culture

(2012) Shu Shyan Wong et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Shining a Light on Xeroderma Pigmentosum

(2012) John J. DiGiovanna et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Polymorphisms in Nevus-Associated Genes MTAP, PLA2G6, and IRF4 and the Risk of Invasive Cutaneous Melanoma

(2012) Marina Kvaskoff et al.   Twin Research and Human Genetics

A Germline Variant in the Interferon Regulatory Factor 4 Gene as a Novel Skin Cancer Risk Locus

(2011) J. Han et al.   CANCER RESEARCH

Genome-wide association study identifies novel alleles associated with risk of cutaneous basal cell carcinoma and squamous cell carcinoma

(2011) Hongmei Nan et al.   HUMAN MOLECULAR GENETICS

Genome-wide association study identifies three new melanoma susceptibility loci

(2011) Jennifer H Barrett et al.   NATURE GENETICS

Detecting Low Frequent Loss-of-Function Alleles in Genome Wide Association Studies with Red Hair Color as Example

(2011) Fan Liu et al.   PLoS One

Hundreds of variants clustered in genomic loci and biological pathways affect human height

(2010) Hana Lango Allen et al.   NATURE

Common SNPs explain a large proportion of the heritability for human height

(2010) Jian Yang et al.   NATURE GENETICS

Variant ofTYRand Autoimmunity Susceptibility Loci in Generalized Vitiligo

(2010) Ying Jin et al.   NEW ENGLAND JOURNAL OF MEDICINE

The genetics of generalized vitiligo: autoimmune pathways and an inverse relationship with malignant melanoma

(2010) Richard A Spritz   Genome Medicine

Digital Quantification of Human Eye Color Highlights Genetic Association of Three New Loci

(2010) Fan Liu et al.   PLoS Genetics

Web-Based, Participant-Driven Studies Yield Novel Genetic Associations for Common Traits

(2010) Nicholas Eriksson et al.   PLoS Genetics

MUM1/IRF4

(2010) Gabriela Gualco et al.   APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY

αMSH and Cyclic AMP Elevating Agents Control Melanosome pH through a Protein Kinase A-independent Mechanism

(2009) Yann Cheli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-Wide Association Study of Tanning Phenotype in a Population of European Ancestry

(2009) Hongmei Nan et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

New common variants affecting susceptibility to basal cell carcinoma

(2009) Simon N Stacey et al.   NATURE GENETICS

Genome-wide association study identifies three loci associated with melanoma risk

(2009) D Timothy Bishop et al.   NATURE GENETICS

Three Genome-wide Association Studies and a Linkage Analysis Identify HERC2 as a Human Iris Color Gene

(2008) Manfred Kayser et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Four novel human betapapillomaviruses of species 2 preferentially found in actinic keratosis

(2008) N. Vasiljevic et al.   JOURNAL OF GENERAL VIROLOGY

ASIP and TYR pigmentation variants associate with cutaneous melanoma and basal cell carcinoma

(2008) Daniel F Gudbjartsson et al.   NATURE GENETICS

Two newly identified genetic determinants of pigmentation in Europeans

(2008) Patrick Sulem et al.   NATURE GENETICS

A Genome-Wide Association Study Identifies Novel Alleles Associated with Hair Color and Skin Pigmentation

(2008) Jiali Han et al.   PLoS Genetics