Programmed death ligand 1 promotes lymph node metastasis and glucose metabolism in cervical cancer by activating integrin β4/SNAI1/SIRT3 signaling pathway

Integrins and Cell Metabolism: An Intimate Relationship Impacting Cancer

(2017) Rehman Ata et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The clinical significance and underlying correlation of pStat-3 and integrin αvβ6 expression in gallbladder cancer

(2017) Liu Enyu et al.   Oncotarget

The significance of programmed cell death ligand 1 expression in resected lung adenocarcinoma

(2017) Shafei Wu et al.   Oncotarget

Frequent PD-L1 expression in primary and metastatic penile squamous cell carcinoma: potential opportunities for immunotherapeutic approaches

(2016) A. M. Udager et al.   ANNALS OF ONCOLOGY

Cancer statistics in China, 2015

(2016) Wanqing Chen et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Tumor-Intrinsic PD-L1 Signals Regulate Cell Growth, Pathogenesis, and Autophagy in Ovarian Cancer and Melanoma

(2016) Curtis A. Clark et al.   CANCER RESEARCH

FBW7 (F-box and WD Repeat Domain-Containing 7) Negatively Regulates Glucose Metabolism by Targeting the c-Myc/TXNIP (Thioredoxin-Binding Protein) Axis in Pancreatic Cancer

(2016) S. Ji et al.   CLINICAL CANCER RESEARCH

The PD-1/PD-L1 axis contributes to immune metabolic dysfunctions of monocytes in chronic lymphocytic leukemia

(2016) M Qorraj et al.   LEUKEMIA

MYC regulates the antitumor immune response through CD47 and PD-L1

(2016) S. C. Casey et al.   SCIENCE

PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinations

(2016) Weiping Zou et al.   Science Translational Medicine

The role of PD-L1 in the radiation response and prognosis for esophageal squamous cell carcinoma related to IL-6 and T-cell immunosuppression

(2016) Miao-Fen Chen et al.   Oncotarget

Bufalin enhances antitumor effect of paclitaxel on cervical tumorigenesis via inhibiting the integrin α2/β5/FAK signaling pathway

(2016) Fei Liu et al.   Oncotarget

Prognostic value of the Hippo pathway transcriptional coactivators YAP/TAZ and β1-integrin in conventional osteosarcoma

(2016) Corinne Bouvier et al.   Oncotarget

Programmed death-ligand 1 overexpression is a prognostic marker for aggressive papillary thyroid cancer and its variants

(2016) Subrata Chowdhury et al.   Oncotarget

Genetic Basis for PD-L1 Expression in Squamous Cell Carcinomas of the Cervix and Vulva

(2016) Brooke E. Howitt et al.   JAMA Oncology

Recent Insight into the Role of the PD-1/PD-L1 Pathway in Feto-Maternal Tolerance and Pregnancy

(2015) Yong-Hong Zhang et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

IL10 and PD-1 Cooperate to Limit the Activity of Tumor-Specific CD8+ T Cells

(2015) Z. Sun et al.   CANCER RESEARCH

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression

(2015) Chih-Hao Chang et al.   CELL

α5β1 integrin recycling promotes Arp2/3-independent cancer cell invasion via the formin FHOD3

(2015) Nikki R. Paul et al.   JOURNAL OF CELL BIOLOGY

PD-L1 induces epithelial-to-mesenchymal transition via activating SREBP-1c in renal cell carcinoma

(2015) Yiwei Wang et al.   MEDICAL ONCOLOGY

Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

Sentinel lymph node metastases in cancer: Causes, detection and their role in disease progression

(2015) S.D. Nathanson et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Integrins and cancer: regulators of cancer stemness, metastasis, and drug resistance

(2015) Laetitia Seguin et al.   TRENDS IN CELL BIOLOGY

High PD-L1 expression was associated with poor prognosis in 870 Chinese patients with breast cancer

(2015) Tao Qin et al.   Oncotarget

Fibrillin-1, induced by Aurora-A but inhibited by BRCA2, promotes ovarian cancer metastasis

(2015) Ziliang Wang et al.   Oncotarget

Nodal metastasis in cervical cancer occurs in clearly delineated fields of immune suppression in the pelvic lymph catchment area

(2015) A. Marijne Heeren et al.   Oncotarget

PD-L1 and Survival in Solid Tumors: A Meta-Analysis

(2015) Pin Wu et al.   PLoS One

Micrometastatic cancer cells in lymph nodes, bone marrow, and blood: Clinical significance and biologic implications

(2014) Stanley P.L. Leong et al.   CA-A CANCER JOURNAL FOR CLINICIANS

The PD-1/PD-Ls pathway and autoimmune diseases

(2014) Suya Dai et al.   CELLULAR IMMUNOLOGY

PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation

(2014) Muhammad Zaeem Noman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

High and Interrelated Rates of PD-L1+CD14+ Antigen-Presenting Cells and Regulatory T Cells Mark the Microenvironment of Metastatic Lymph Nodes from Patients with Cervical Cancer

(2014) A. M. Heeren et al.   Cancer Immunology Research

SIRT3 Controls Cancer Metabolic Reprogramming by Regulating ROS and HIF

(2011) Paul T. Schumacker   CANCER CELL

SIRT3 Opposes Reprogramming of Cancer Cell Metabolism through HIF1α Destabilization

(2011) Lydia W.S. Finley et al.   CANCER CELL

SIRT3 Is a Mitochondria-Localized Tumor Suppressor Required for Maintenance of Mitochondrial Integrity and Metabolism during Stress

(2010) Hyun-Seok Kim et al.   CANCER CELL

B7-H1 Overexpression Regulates Epithelial–Mesenchymal Transition and Accelerates Carcinogenesis in Skin

(2010) Yujia Cao et al.   CANCER RESEARCH

Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling

(2010) Eric Verdin et al.   TRENDS IN BIOCHEMICAL SCIENCES

Genetic, immunologic, and immunohistochemical analysis of the programmed death 1/programmed death ligand 1 pathway in human systemic lupus erythematosus

(2009) George K. Bertsias et al.   ARTHRITIS AND RHEUMATISM

Overexpression of PD-L1 Significantly Associates with Tumor Aggressiveness and Postoperative Recurrence in Human Hepatocellular Carcinoma

(2009) Q. Gao et al.   CLINICAL CANCER RESEARCH

PD-1 and Its Ligands in Tolerance and Immunity

(2008) Mary E. Keir et al.   Annual Review of Immunology

PD-1 ligands expressed on myeloid-derived APC in the CNS regulate T-cell responses in EAE

(2008) Bettina Schreiner et al.   EUROPEAN JOURNAL OF IMMUNOLOGY