Novel identification of STAT1 as a crucial mediator of ETV6-NTRK3-induced tumorigenesis

Transcriptome sequencing identifiesETV6-NTRK3as a gene fusion involved in GIST

(2016) Monica Brenca et al.   JOURNAL OF PATHOLOGY

“Wild type” GIST: Clinicopathological features and clinical practice

(2016) Ryuichi Wada et al.   PATHOLOGY INTERNATIONAL

The JAK-STAT Pathway: Impact on Human Disease and Therapeutic Intervention

(2015) John J. O'Shea et al.   Annual Review of Medicine

Dynamic aberrant NF-κB spurs tumorigenesis: A new model encompassing the microenvironment

(2015) Spiros A. Vlahopoulos et al.   CYTOKINE & GROWTH FACTOR REVIEWS

STAT transcript levels in childhood acute lymphoblastic leukemia: STAT1 and STAT3 transcript correlations

(2015) Maria Adamaki et al.   LEUKEMIA RESEARCH

High STAT1 mRNA levels but not its tyrosine phosphorylation are associated with macrophage infiltration and bad prognosis in breast cancer

(2014) Piotr Tymoszuk et al.   BMC CANCER

Causal analysis approaches in Ingenuity Pathway Analysis

(2013) Andreas Krämer et al.   BIOINFORMATICS

SignaLink 2 – a signaling pathway resource with multi-layered regulatory networks

(2013) Dávid Fazekas et al.   BMC Systems Biology

ALK inhibitors in the treatment of advanced NSCLC

(2013) Cesare Gridelli et al.   CANCER TREATMENT REVIEWS

Mutation of the Salt Bridge-forming Residues in the ETV6-SAM Domain Interface Blocks ETV6-NTRK3-induced Cellular Transformation

(2013) Naniye Cetinbas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tumor STAT1 Transcription Factor Activity Enhances Breast Tumor Growth and Immune Suppression Mediated by Myeloid-derived Suppressor Cells

(2013) Laura M. Hix et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Architecture of the human regulatory network derived from ENCODE data

(2012) Mark B. Gerstein et al.   NATURE

H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs

(2012) Jiekai Chen et al.   NATURE GENETICS

The co-regulation mechanism of transcription factors in the human gene regulatory network

(2012) Junil Kim et al.   NUCLEIC ACIDS RESEARCH

Microarrays, deep sequencing and the true measure of the transcriptome

(2011) John H Malone et al.   BMC BIOLOGY

The Two Faces of Interferon-  in Cancer

(2011) M. R. Zaidi et al.   CLINICAL CANCER RESEARCH

ETV6-NTRK3-Mediated Breast Epithelial Cell Transformation Is Blocked by Targeting the IGF1R Signaling Pathway

(2010) C. E. Tognon et al.   CANCER RESEARCH

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

RNA-Seq gene expression estimation with read mapping uncertainty

(2009) Bo Li et al.   BIOINFORMATICS

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

A phosphorylation-acetylation switch regulates STAT1 signaling

(2009) O. H. Kramer et al.   GENES & DEVELOPMENT

Phosphorylation–acetylation switch in the regulation of STAT1 signaling

(2009) Oliver H. Krämer et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

RNA-Seq: a revolutionary tool for transcriptomics

(2008) Zhong Wang et al.   NATURE REVIEWS GENETICS

An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer

(2008) R. R. Weichselbaum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA