Identifying the biological pathways underlying human focal epilepsy: from complexity to coherence to centrality

Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus

(2015) Michael R. Johnson et al.   Nature Communications

DrugComboRanker: drug combination discovery based on target network analysis

(2014) L. Huang et al.   BIOINFORMATICS

Describing the genetic architecture of epilepsy through heritability analysis

(2014) Doug Speed et al.   BRAIN

A validation of the new definition of drug-resistant epilepsy by the International League Against Epilepsy

(2014) Jose F. Téllez-Zenteno et al.   EPILEPSIA

Mendelian genes for Parkinson's disease contribute to the sporadic forms of the disease†

(2014) Nino Spataro et al.   HUMAN MOLECULAR GENETICS

Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies

(2014)   LANCET NEUROLOGY

Drug treatment of epilepsy in adults

(2014) D. Schmidt et al.   BMJ-British Medical Journal

Integrative Functional Genomic Analyses Implicate Specific Molecular Pathways and Circuits in Autism

(2013) Neelroop N. Parikshak et al.   CELL

Dissection of Regulatory Networks that Are Altered in Disease via Differential Co-expression

(2013) David Amar et al.   PLoS Computational Biology

A System-Level Transcriptomic Analysis of Schizophrenia Using Postmortem Brain Tissue Samples

(2012) Panos Roussos et al.   ARCHIVES OF GENERAL PSYCHIATRY

The mu-opioid receptor-selective peptide antagonists, antanal-1 and antanal-2, produce anticonvulsant effects in mice

(2012) Jakub Fichna et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Independent surrogate variable analysis to deconvolve confounding factors in large-scale microarray profiling studies

(2011) Andrew E. Teschendorff et al.   BIOINFORMATICS

Exploring pathway interactions in insulin resistant mouse liver

(2011) Thomas Kelder et al.   BMC Systems Biology

Exploring the genomic basis of pharmacoresistance in epilepsy: an integrative analysis of large-scale gene expression profiling studies on brain tissue from epilepsy surgery

(2011) Nasir Mirza et al.   HUMAN MOLECULAR GENETICS

Activation of κ opioid receptors increases intrinsic excitability of dentate gyrus granule cells

(2011) Carmel M. McDermott et al.   JOURNAL OF PHYSIOLOGY-LONDON

Dynamics of Short-Term Gene Expression Profiling in Liver Following Thermal Injury

(2011) Qian Yang et al.   JOURNAL OF SURGICAL RESEARCH

Transcriptomic analysis of autistic brain reveals convergent molecular pathology

(2011) Irina Voineagu et al.   NATURE

Decreased CREB levels suppress epilepsy

(2011) Xinjian Zhu et al.   NEUROBIOLOGY OF DISEASE

Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study

(2010) Dalia Kasperavičiūtė et al.   BRAIN

Revised terminology and concepts for organization of seizures and epilepsies: Report of the ILAE Commission on Classification and Terminology, 2005-2009

(2010) Anne T. Berg et al.   EPILEPSIA

Mu opioid receptor mRNA expression, binding, and functional coupling to G-proteins in human epileptic hippocampus

(2010) Manola Cuellar-Herrera et al.   HIPPOCAMPUS

A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk

(2010) Matthias Heinig et al.   NATURE

GSA-SNP: a general approach for gene set analysis of polymorphisms

(2010) Dougu Nam et al.   NUCLEIC ACIDS RESEARCH

Preliminary Exploration of Time Course DNA Microarray Data with Correlation Maps

(2010) Robert M. Flight et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Enrichment Map: A Network-Based Method for Gene-Set Enrichment Visualization and Interpretation

(2010) Daniele Merico et al.   PLoS One

Statistical methods for gene set co-expression analysis

(2009) YounJeong Choi et al.   BIOINFORMATICS

Dissecting the dynamics of dysregulation of cellular processes in mouse mammary gland tumor

(2009) Wieslawa I Mentzen et al.   BMC GENOMICS

A global pathway crosstalk network

(2008) Yong Li et al.   BIOINFORMATICS

Identifying gene-disease associations using centrality on a literature mined gene-interaction network

(2008) A. Ozgur et al.   BIOINFORMATICS

Overexpression of N-WASP in the brain of human epilepsy

(2008) Fei Xiao et al.   BRAIN RESEARCH

Possible role of the innate immunity in temporal lobe epilepsy

(2008) Koen L.I. van Gassen et al.   EPILEPSIA

Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set

(2008) Winnie S. Liang et al.   PHYSIOLOGICAL GENOMICS

Intrinsic Severity as a Determinant of Antiepileptic Drug Refractoriness

(2008) Michael A. Rogawski et al.   Epilepsy Currents