COX-2 mediates pro-tumorigenic effects of PKCε in prostate cancer

The prognostic value of cyclooxygenase-2 expression in patients with esophageal cancer: evidence from a meta-analysis

(2017) Zaoxiu Hu et al.   OncoTargets and Therapy

Protein Kinase C Epsilon Cooperates with PTEN Loss for Prostate Tumorigenesis through the CXCL13-CXCR5 Pathway

(2017) Rachana Garg et al.   Cell Reports

Mutations in PIK3CA sensitize breast cancer cells to physiologic levels of aspirin

(2016) Sanja B. Turturro et al.   BREAST CANCER RESEARCH AND TREATMENT

Aspirin Suppresses Growth in PI3K-Mutant Breast Cancer by Activating AMPK and Inhibiting mTORC1 Signaling

(2016) Whitney S. Henry et al.   CANCER RESEARCH

Prostaglandin E2 and the EP receptors in malignancy: possible therapeutic targets?

(2015) G O'Callaghan et al.   BRITISH JOURNAL OF PHARMACOLOGY

mPGES-1 in prostate cancer controls stemness and amplifies epidermal growth factor receptor-driven oncogenicity

(2015) Federica Finetti et al.   ENDOCRINE-RELATED CANCER

PKC  Is an Essential Mediator of Prostate Cancer Bone Metastasis

(2015) A. Gutierrez-Uzquiza et al.   MOLECULAR CANCER RESEARCH

Transcriptional Regulation of Oncogenic Protein Kinase Cϵ (PKCϵ) by STAT1 and Sp1 Proteins

(2014) HongBin Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

EP2 signaling mediates suppressive effects of celecoxib on androgen receptor expression and cell proliferation in prostate cancer

(2014) E Kashiwagi et al.   PROSTATE CANCER AND PROSTATIC DISEASES

The Multifunctional Protein Kinase C-ε in Cancer Development and Progression

(2014) Kirti Jain et al.   Cancers

Cyclooxygenase-2 inhibitor suppresses tumour progression of prostate cancer bone metastases in nude mice

(2013) Marta Garcia et al.   BJU INTERNATIONAL

Aspirin and Colorectal Cancer: Back to the Future

(2013) David Tougeron et al.   CLINICAL CANCER RESEARCH

Prostaglandin receptor EP3 mediates growth inhibitory effect of aspirin through androgen receptor and contributes to castration resistance in prostate cancer cells

(2013) Eiji Kashiwagi et al.   ENDOCRINE-RELATED CANCER

Protein Kinase C -Calcineurin Cosignaling Downstream of Toll-Like Receptor 4 Downregulates Fibrosis and Induces Wound Healing Gene Expression in Cardiac Myofibroblasts

(2013) R. F. D. S. Mesquita et al.   MOLECULAR AND CELLULAR BIOLOGY

Protein kinase C and cancer: what we know and what we do not

(2013) R Garg et al.   ONCOGENE

Prostaglandin receptor EP2 in the crosshairs of anti-inflammation, anti-cancer, and neuroprotection

(2013) Jianxiong Jiang et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Selenium-containing histone deacetylase inhibitors for melanoma management

(2012) Raghavendra Gowda et al.   CANCER BIOLOGY & THERAPY

Use of aspirin, but not other non-steroidal anti-inflammatory drugs is associated with decreased prostate cancer risk at the population level

(2012) Thea Veitonmäki et al.   EUROPEAN JOURNAL OF CANCER

The atypical PKCs in inflammation: NF-κB and beyond

(2012) Maria T. Diaz-Meco et al.   IMMUNOLOGICAL REVIEWS

Activation of Nuclear Factor κB (NF-κB) in Prostate Cancer Is Mediated by Protein Kinase C ϵ (PKCϵ)

(2012) Rachana Garg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The STAMPEDE trial and celecoxib: how to adapt?

(2012) Andrew J Armstrong   LANCET ONCOLOGY

Celecoxib plus hormone therapy versus hormone therapy alone for hormone-sensitive prostate cancer: first results from the STAMPEDE multiarm, multistage, randomised controlled trial

(2012) Nicholas D James et al.   LANCET ONCOLOGY

Aspirin Use, TumorPIK3CAMutation, and Colorectal-Cancer Survival

(2012) Xiaoyun Liao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Non-Small Cell Lung Carcinoma Cell Motility, Rac Activation and Metastatic Dissemination Are Mediated by Protein Kinase C Epsilon

(2012) M. Cecilia Caino et al.   PLoS One

Genetic Ablation of PKC Epsilon Inhibits Prostate Cancer Development and Metastasis in Transgenic Mouse Model of Prostate Adenocarcinoma

(2011) B. B. Hafeez et al.   CANCER RESEARCH

Transgenic overexpression of PKCε in the mouse prostate induces preneoplastic lesions

(2011) Fernando Benavides et al.   CELL CYCLE

Proteins kinase Cɛ is required for non-small cell lung carcinoma growth and regulates the expression of apoptotic genes

(2011) M C Caino et al.   ONCOGENE

COX-2 is overexpressed in primary prostate cancer with metastatic potential and may predict survival. A comparison study between COX-2, TGF-β, IL-10 and Ki67

(2010) Elin Richardsen et al.   Cancer Epidemiology

Atorvastatin and Celecoxib in Combination Inhibits the Progression of Androgen-Dependent LNCaP Xenograft Prostate Tumors to Androgen Independence

(2010) X. Zheng et al.   Cancer Prevention Research

NF-κB Signaling Pathway, Inflammation and Colorectal Cancer

(2010) Soly Wang et al.   Cellular & Molecular Immunology

Regression of prostate tumors upon combination of hormone ablation therapy and celecoxib in vivo

(2010) Parisa Abedinpour et al.   PROSTATE

Modular therapy approach in metastatic castration-refractory prostate cancer

(2010) B. Walter et al.   WORLD JOURNAL OF UROLOGY

Protein Kinase C  Activates RelA/p65 and Nuclear Factor- B Signaling in Response to Tumor Necrosis Factor- 

(2009) Z.-G. Lu et al.   CANCER RESEARCH

Protein kinase Cε: an oncogene and emerging tumor biomarker

(2009) Michael A Gorin et al.   Molecular Cancer

The role of COX-2 in intestinal inflammation and colorectal cancer

(2009) D Wang et al.   ONCOGENE

aPKC /  promotes growth of prostate cancer cells in an autocrine manner through transcriptional activation of interleukin-6

(2009) H. Ishiguro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Simultaneous inactivation of Par-4 and PTEN in vivo leads to synergistic NF- B activation and invasive prostate carcinoma

(2009) P. J. Fernandez-Marcos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microsomal prostaglandin E synthase 1 determines tumor growth in vivo of prostate and lung cancer cells

(2009) H. Hanaka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyclooxygenase-2 (cox-2) blockade in the chemoprevention of cancers of the colon, breast, prostate, and lung

(2009) R. E. Harris   INFLAMMOPHARMACOLOGY

Prostaglandin E2 Regulates Tumor Angiogenesis in Prostate Cancer

(2008) S. Jain et al.   CANCER RESEARCH

Phorbol ester-stimulated NF-κB-dependent transcription: Roles for isoforms of novel protein kinase C

(2008) Neil S. Holden et al.   CELLULAR SIGNALLING

Cyclooxygenase-2 Expression Is an Independent Predictor of Poor Prognosis in Colon Cancer

(2008) S. Ogino et al.   CLINICAL CANCER RESEARCH

A new prostate cancer therapeutic approach: Combination of androgen ablation with COX-2 inhibitor

(2008) Yi Cai et al.   INTERNATIONAL JOURNAL OF CANCER