Dynamin-2 mutations associated with centronuclear myopathy are hypermorphic and lead to T-tubule fragmentation

BAR Domain Scaffolds in Dynamin-Mediated Membrane Fission

(2014) Oliver Daumke et al.   CELL

Actin scaffolding by clathrin heavy chain is required for skeletal muscle sarcomere organization

(2014) Stéphane Vassilopoulos et al.   JOURNAL OF CELL BIOLOGY

Reducing dynamin 2 expression rescues X-linked centronuclear myopathy

(2014) Belinda S. Cowling et al.   JOURNAL OF CLINICAL INVESTIGATION

The myopathy-causing mutation DNM2-S619L leads to defective tubulation in vitro and in developing zebrafish

(2013) E. M. Gibbs et al.   Disease Models & Mechanisms

The myotubularin–amphiphysin 2 complex in membrane tubulation and centronuclear myopathies

(2013) Barbara Royer et al.   EMBO REPORTS

Dual Role of BAR Domain-containing Proteins in Regulating Vesicle Release Catalyzed by the GTPase, Dynamin-2

(2013) Sylvia Neumann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cooperative Recruitment of Dynamin and BIN/Amphiphysin/Rvs (BAR) Domain-containing Proteins Leads to GTP-dependent Membrane Scission

(2013) Michael Meinecke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuromuscular junction abnormalities in DNM2-related centronuclear myopathy

(2013) Elizabeth M. Gibbs et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Analyzing membrane remodeling and fission using supported bilayers with excess membrane reservoir

(2013) Sylvia Neumann et al.   Nature Protocols

Dynamin 2 mutations in Charcot–Marie–Tooth neuropathy highlight the importance of clathrin-mediated endocytosis in myelination

(2012) Páris N. M. Sidiropoulos et al.   BRAIN

Mutation spectrum in the large GTPase dynamin 2, and genotype-phenotype correlation in autosomal dominant centronuclear myopathy

(2012) Johann Böhm et al.   HUMAN MUTATION

Dynamin, a membrane-remodelling GTPase

(2012) Shawn M. Ferguson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural Insights into Dynamin-Mediated Membrane Fission

(2012) Katja Faelber et al.   STRUCTURE

Defective Membrane Remodeling in Neuromuscular Diseases: Insights from Animal Models

(2012) Belinda S. Cowling et al.   PLoS Genetics

Increased Expression of Wild-Type or a Centronuclear Myopathy Mutant of Dynamin 2 in Skeletal Muscle of Adult Mice Leads to Structural Defects and Muscle Weakness

(2011) Belinda S. Cowling et al.   AMERICAN JOURNAL OF PATHOLOGY

A Pseudoatomic Model of the Dynamin Polymer Identifies a Hydrolysis-Dependent Powerstroke

(2011) Joshua S. Chappie et al.   CELL

Crystal structure of nucleotide-free dynamin

(2011) Katja Faelber et al.   NATURE

Molecular mechanism and physiological functions of clathrin-mediated endocytosis

(2011) Harvey T. McMahon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mild Functional Differences of Dynamin 2 Mutations Associated to Centronuclear Myopathy and Charcot-Marie-Tooth Peripheral Neuropathy

(2011) Olga S. Koutsopoulos et al.   PLoS One

Differential curvature sensing and generating activities of dynamin isoforms provide opportunities for tissue-specific regulation

(2011) Y.-W. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T-tubule biogenesis and triad formation in skeletal muscle and implication in human diseases

(2011) Lama Al-Qusairi et al.   Skeletal Muscle

Defects in amphiphysin 2 (BIN1) and triads in several forms of centronuclear myopathies

(2010) Anne Toussaint et al.   ACTA NEUROPATHOLOGICA

Supported Bilayers with Excess Membrane Reservoir: A Template for Reconstituting Membrane Budding and Fission

(2010) Thomas J. Pucadyil et al.   BIOPHYSICAL JOURNAL

Direct dynamin–actin interactions regulate the actin cytoskeleton

(2010) Changkyu Gu et al.   EMBO JOURNAL

Dynamin GTPase regulation is altered by PH domain mutations found in centronuclear myopathy patients

(2010) Jon A Kenniston et al.   EMBO JOURNAL

A centronuclear myopathy-dynamin 2 mutation impairs skeletal muscle structure and function in mice

(2010) Anne-Cécile Durieux et al.   HUMAN MOLECULAR GENETICS

Dynamin 2 Mutants Linked to Centronuclear Myopathies Form Abnormally Stable Polymers

(2010) Lei Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamin 2 and human diseases

(2010) Anne-Cécile Durieux et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

G domain dimerization controls dynamin's assembly-stimulated GTPase activity

(2010) Joshua S. Chappie et al.   NATURE

Dissecting dynamin's role in clathrin-mediated endocytosis

(2009) Marcel Mettlen et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Membrane Insertion of the Pleckstrin Homology Domain Variable Loop 1 Is Critical for Dynamin-catalyzed Vesicle Scission

(2009) Rajesh Ramachandran et al.   MOLECULAR BIOLOGY OF THE CELL

Cargo and Dynamin Regulate Clathrin-Coated Pit Maturation

(2009) Dinah Loerke et al.   PLOS BIOLOGY

Isoform and Splice-Variant Specific Functions of Dynamin-2 Revealed by Analysis of Conditional Knock-Out Cells

(2008) Ya-Wen Liu et al.   MOLECULAR BIOLOGY OF THE CELL

Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes

(2008) Michele Markstein et al.   NATURE GENETICS

Membrane Traffic and Muscle: Lessons from Human Disease

(2008) James J. Dowling et al.   TRAFFIC