Article
Pediatrics
Chitmandeep Josan, Samantha Shiplo, Gerhard Fusch, Sandeep Raha, Alison K. Shea
Summary: This study investigates the effects of maternal cannabis use on the levels of macronutrients and bioactive factors in breast milk. The results show that cannabinoids are present in the milk of cannabis users, accompanied by increased lactose levels and decreased SIgA levels, which may have significant implications for infant health.
PEDIATRIC RESEARCH
(2023)
Article
Chemistry, Applied
Julie Hoova, Ines Velasco Lopez, Eduardo Garcia Soblechero, Ana Arias-Borrego, Tamara Garcia-Barrera
Summary: Selenoprotein P is found in human breast milk and plays a crucial role in selenium transfer during lactation. Concentration of selenium in maternal serum is higher than cord serum and breast milk, with glutathione peroxidase mainly transferred through breast milk.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2021)
Article
Pharmacology & Pharmacy
Natalie Dinavitser, Elkana Kohn, Maya Berlin, Nurit Brandriss, Adina Bar-Chaim, Rimona Keidar, Ayelet Livne, David Stepensky, Matitiahu Berkovitch, Revital Sheinberg
Summary: This study examined the excretion of levetiracetam in breastmilk in breastfeeding women with epilepsy, finding that exposure to the drug in breastmilk may lead to infant toxicities. The study also revealed a close correlation between levetiracetam dose, maternal serum concentration, and breastmilk levels. Further studies are needed to assess the short- and long-term safety of levetiracetam in breastfeeding infants.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2022)
Article
Obstetrics & Gynecology
Palika Datta, Avery Bramnik, Kathleen Rewers-Felkins, Kaytlin Krutsch, Teresa Baker, Thomas W. Hale
Summary: Studies indicate that high levels of apixaban are transferred into breast milk, suggesting that breastfeeding women may prefer other anticoagulants.
OBSTETRICS AND GYNECOLOGY
(2021)
Article
Nursing
Cosima Lisi, Claudia De Freitas, Henrique Barros
Summary: This study used high performance liquid chromatography mass spectrometry to analyze the concentration of cetirizine in human milk and found a relative infant dose of 1.77% at 24 hr. Additionally, no adverse effects were reported in the infants. The study suggests that transfer of cetirizine into human milk is minimal and unlikely to pose a significant risk to breastfeeding infants.
JOURNAL OF HUMAN LACTATION
(2021)
Article
Nursing
Hannah Wilkerson, Palika Datta, Kathleen Rewers-Felkins, Teresa Baker, Thomas W. Hale
Summary: The study used high performance liquid chromatography mass spectrometry to analyze the concentration of cetirizine in human milk. The relative infant dose was calculated to be 1.77% at 24 hr, with no reported adverse effects in infants. This study suggests that the transfer of cetirizine into human milk is minimal and unlikely to pose a significant risk to breastfeeding infants.
JOURNAL OF HUMAN LACTATION
(2021)
Article
Immunology
Katrin Lazar, Thorsten Kussmann, Graham Pawelec, Simone Poeschel, Rangmar Goelz, Klaus Hamprecht, Kilian Wistuba-Hamprecht
Summary: The presence of lymphocyte subsets in breast milk may be more influenced by the HCMV-seropositivity of the mother than previously recognized, as evidenced by significantly higher T cell frequencies in the mature milk of HCMV-seropositive mothers compared to seronegative mothers.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Pediatrics
Michael J. Moss, Ittai Bushlin, Steven Kazmierczak, Dennis Koop, Robert G. Hendrickson, Katharine E. Zuckerman, Tamara M. Grigsby
Summary: This study quantified cannabinoids in plasma and breast milk of breastfeeding mothers and found that THC and CBD accumulate in breast milk. It also showed that breastfeeding mothers tend to increase cannabis use in the early postpartum period. Further research is needed to evaluate infant exposure to cannabinoids via breast milk and its effects on infant health.
PEDIATRIC RESEARCH
(2021)
Article
Pharmacology & Pharmacy
Siri Amundsen, Hedvig Nordeng, Ole-Martin Fuskevag, Elisabet Nordmo, Georg Sager, Olav Spigset
Summary: This study investigated the excretion of six different triptans into human breast milk among 19 breastfeeding women with migraine. The results showed that infant drug exposure through breastfeeding is low and indicates compatibility of triptans with breastfeeding. Naratriptan may not be the first choice for breastfeeding mothers initiating triptans during the neonatal period.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
(2021)
Article
Medicine, General & Internal
Nazeeh Hanna, Claudia Manzano De Mejia, Ari Heffes-Doon, Xinhua Lin, Bishoy Botros, Ellen Gurzenda, Christie Clauss-Pascarelli, Amrita Nayak
Summary: This study evaluated the presence and potential translational activity of COVID-19 vaccine mRNA in breast milk of lactating women. The results showed that while trace amounts of vaccine mRNA were detectable in breast milk, it was not expressed in breast milk extracellular vesicles and did not induce its expression in cells. Therefore, breastfeeding after 48 hours of vaccination is considered safe.
Article
Food Science & Technology
Miroslava Jandova, Michaela Fiserova, Pavla Paterova, Lucie Cackova, Pavel Mericka, Jan Maly, Marian Kacerovsky, Eliska Kovarikova, Jan Strohalm, Katerina Demnerova, Jana Kadava, Hana Sykorova, Radomir Hyspler, Dana Cizkova, Ales Bezrouk, Milan Houska
Summary: The study aimed to find an alternative method for processing breast milk to increase its availability and reduce waste. It found that pressure in cycles was more effective in reducing spore count compared to cumulative pressure, and the method was reproducible. The use of this method could increase the availability of milk for newborns and preserve its nutritional quality.
Article
Agriculture, Dairy & Animal Science
Mahmoud K. Eldahshoury, Ian P. Hurley
Summary: The demand for commercially available human breast milk has been increasing lately, and there is a concern that it is being adulterated with other types of milk. This fraudulent practice can put infants at risk due to potential intolerance or allergy to cow milk. To address this issue, a specific and sensitive assay called the direct sandwich anti-bovine IgG ELISA has been developed, which is able to detect even a small amount of cow milk in adulterated human breast milk.
JOURNAL OF DAIRY SCIENCE
(2023)
Article
Veterinary Sciences
Wenhao Li, Weike Zeng, Yanping Zhang, Zhijie Ma, Xingyan Fang, Yingcang Han, Yonggang Sun, Xiayang Jin, Liuyin Ma
Summary: This study investigates the metabolite composition of yak milk and its role in hypoxic stress tolerance, comparing it to human milk. The results show that yak milk relies on certain essential amino acids to tolerate hypoxic stress, while human milk utilizes neuroprotective effects of non-essential amino acids or derivates. Additionally, metabolites related to hypoxic stress are more abundant in yak colostrum compared to yak mature milk.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Article
Microbiology
Margherita D'Alessandro, Carola Parolin, Silvia Patrignani, Gilda Sottile, Patrizio Antonazzo, Beatrice Vitali, Rosalba Lanciotti, Francesca Patrignani
Summary: This study focuses on the isolation and characterization of lactobacilli/bifidobacteria from human breast milk to find new probiotic candidates for food products. The breast milk strains demonstrate good adhesion to intestinal cells, antagonistic activity against food spoilage and pathogenic species, and the potential to release aroma compounds associated with sensory quality of dairy products.
Review
Immunology
Lina Tingo, Emelie Ahlberg, Lovisa Johansson, Sindre Andre Pedersen, Konika Chawla, Pal Saetrom, Erika Cione, Melanie Rae Simpson
Summary: Breast milk contains a variety of RNA types, including miRNAs, with some miRNAs being widely reported across different fractions. It is currently challenging to determine which factors influence the characteristics of the miRNA profile, but studies suggest that certain miRNAs are highly expressed and stable in breast milk. Future research needs to further explore the biological effects of miRNAs in breast milk and characterize other ncRNAs.
FRONTIERS IN IMMUNOLOGY
(2021)