The mechanisms of a mammalian splicing enhancer

Saturation mutagenesis reveals manifold determinants of exon definition

(2017) Shengdong Ke et al.   GENOME RESEARCH

Mutations of Pre-mRNA Splicing Regulatory Elements: Are Predictions Moving Forward to Clinical Diagnostics?

(2017) Lucie Grodecká et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Pathogenic variants that alter protein code often disrupt splicing

(2017) Rachel Soemedi et al.   NATURE GENETICS

Rbfox Proteins Regulate Splicing as Part of a Large Multiprotein Complex LASR

(2016) Andrey Damianov et al.   CELL

The complete local genotype–phenotype landscape for the alternative splicing of a human exon

(2016) Philippe Julien et al.   Nature Communications

EGFP oligomers as natural fluorescence and hydrodynamic standards

(2016) György Vámosi et al.   Scientific Reports

Large-scale remodeling of a repressed exon ribonucleoprotein to an exon definition complex active for splicing

(2016) Somsakul Pop Wongpalee et al.   eLife

Learning the Sequence Determinants of Alternative Splicing from Millions of Random Sequences

(2015) Alexander B. Rosenberg et al.   CELL

SRSF1-Regulated Alternative Splicing in Breast Cancer

(2015) Olga Anczuków et al.   MOLECULAR CELL

Targeting SR Proteins Improves SMN Expression in Spinal Muscular Atrophy Cells

(2014) Claribel D. Wee et al.   PLoS One

The human splicing code reveals new insights into the genetic determinants of disease

(2014) H. Y. Xiong et al.   SCIENCE

A Targeted Oligonucleotide Enhancer of SMN2 Exon 7 Splicing Forms Competing Quadruplex and Protein Complexes in Functional Conditions

(2014) Lindsay D. Smith et al.   Cell Reports

Pick one, but be quick: 5' splice sites and the problems of too many choices

(2013) X. Roca et al.   GENES & DEVELOPMENT

Genome-wide Analysis Reveals SR Protein Cooperation and Competition in Regulated Splicing

(2013) Shatakshi Pandit et al.   MOLECULAR CELL

A compendium of RNA-binding motifs for decoding gene regulation

(2013) Debashish Ray et al.   NATURE

MBNL1 and PTB cooperate to repress splicing of Tpm1 exon 3

(2013) Clare Gooding et al.   NUCLEIC ACIDS RESEARCH

Single-molecule colocalization FRET evidence that spliceosome activation precedes stable approach of 5' splice site and branch site

(2013) D. J. Crawford et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isolated pseudo-RNA-recognition motifs of SR proteins can regulate splicing using a noncanonical mode of RNA recognition

(2013) A. Clery et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alternative Spliceosome Assembly Pathways Revealed by Single-Molecule Fluorescence Microscopy

(2013) Inna Shcherbakova et al.   Cell Reports

An RNA Splicing Enhancer that Does Not Act by Looping

(2012) Helen Lewis et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and biological properties of chemically modified siRNAs bearing 1-deoxy-d-ribofuranose in their 3′-overhang region

(2012) Kazumi Taniho et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The transition in spliceosome assembly from complex E to complex A purges surplus U1 snRNPs from alternative splice sites

(2012) M. J. Hodson et al.   NUCLEIC ACIDS RESEARCH

Prp2-mediated protein rearrangements at the catalytic core of the spliceosome as revealed by dcFCCS

(2012) T. Ohrt et al.   RNA

Conjugation of PEG and gold nanoparticles to increase the accessibility and valency of tethered RNA splicing enhancers

(2012) Andrew J. Perrett et al.   Chemical Science

The RNA-binding landscapes of two SR proteins reveal unique functions and binding to diverse RNA classes

(2012) Minna-Liisa Änkö et al.   GENOME BIOLOGY

Quantitative evaluation of all hexamers as exonic splicing elements

(2011) Shengdong Ke et al.   GENOME RESEARCH

Molecular basis of purine-rich RNA recognition by the human SR-like protein Tra2-β1

(2011) Antoine Cléry et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Design principles for bifunctional targeted oligonucleotide enhancers of splicing

(2011) N. Owen et al.   NUCLEIC ACIDS RESEARCH

Interaction between the RNA binding domains of Ser-Arg splicing factor 1 and U1-70K snRNP protein determines early spliceosome assembly

(2011) S. Cho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Separation of preferential interaction and excluded volume effects on DNA duplex and hairpin stability

(2011) D. B. Knowles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Using positional distribution to identify splicing elements and predict pre-mRNA processing defects in human genes

(2011) K. H. Lim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ordered and Dynamic Assembly of Single Spliceosomes

(2011) A. A. Hoskins et al.   SCIENCE

Stoichiometry of a regulatory splicing complex revealed by single-molecule analyses

(2010) Dmitry Cherny et al.   EMBO JOURNAL

Antagonistic factors control the unproductive splicing of SC35 terminal intron

(2009) Natacha Dreumont et al.   NUCLEIC ACIDS RESEARCH

The SR protein family

(2009) Peter J Shepard et al.   GENOME BIOLOGY

The SR protein family of splicing factors: master regulators of gene expression

(2008) Jennifer C. Long et al.   BIOCHEMICAL JOURNAL

Splicing factor SFRS1 recognizes a functionally diverse landscape of RNA transcripts

(2008) J. R. Sanford et al.   GENOME RESEARCH