Article
Biochemistry & Molecular Biology
Azizah M. Malebari, Rakia Abd Alhameed, Zainab Almarhoon, Muhammad Farooq, Mohammad A. M. Wadaan, Anamika Sharma, Beatriz G. de la Torre, Fernando Albericio, Ayman El-Faham
Summary: The study synthesized derivatives containing morpholine/piperidine, anilines, and dipeptides, and evaluated their anticancer activity in vitro and in vivo, with one compound showing high cytotoxicity against breast cancer cells.
Article
Biochemistry & Molecular Biology
Firas Obaid Arhema Frejat, Hongjin Zhai, Yaquan Cao, Lihong Wang, Yaser A. Mostafa, Hesham A. M. Gomaa, Bahaa G. M. Youssif, Chunli Wu
Summary: Indazole is an important class of heterocyclic compounds with diverse biological activity. In this study, a novel series of differently substituted indazole derivatives 6a-v were synthesized and evaluated for their biological activity. The results demonstrated that compounds 6f, 6i, 6j, 6s, and 6n exhibited significant antiproliferative activity against cancer cells and showed promising potential as potent antiproliferative agents by inhibiting EGFR, CDK2, and c-Met and inducing apoptosis through cytochrome C overexpression and activation of the intrinsic apoptotic pathway.
BIOORGANIC CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Tinuccia Dettori, Giuseppina Sanna, Andrea Cocco, Gabriele Serreli, Monica Deiana, Vanessa Palmas, Valentina Onnis, Luca Pilia, Nicola Melis, Davide Moi, Paola Caria, Francesco Secci
Summary: This study investigated the antiproliferative effects of a series of halocoumarin derivatives on tumor and normal cell lines. The compound 6,8-dibromo-2-oxo-2H-chromene-3-carbonitrile (2h) and 6,8-diiodo-2-oxo-2H-chromene-3-carbonitrile (2k) exhibited the most potent antiproliferative effect on thyroid cancer cells. The mechanism behind these effects involved apoptosis induction and modulation of ROS levels.
Article
Biochemistry & Molecular Biology
Matteo Lusardi, Aldo Profumo, Chiara Rotolo, Erika Iervasi, Camillo Rosano, Andrea Spallarossa, Marco Ponassi
Summary: A library of highly functionalized phenylaminopyrazoles was synthesized, characterized, and tested for their cell-based activities, showing potential pharmaceutical applications.
Article
Chemistry, Medicinal
Joyce E. Gutierrez, Esteban Fernandez-Moreira, Miguel A. Rodriguez, Michael R. Mijares, Juan Bautista De Sanctis, Sona Gurska, Petr Dzubak, Marian Hajduch, Julia Bruno-Colmenarez, Luis Rojas, Denis Deffieux, Laurent Pouysegu, Stephane Quideau, Jaime Charris, Hegira Ramirez
Summary: Some sulfanyl and sulfinyl derivatives exhibited lower cytotoxicity for cancer cell lines compared to sulfonyl N-oxide derivatives. Compound 81 showed pronounced selectivity for human colorectal cancer cells and leukemia cell lines.
Article
Chemistry, Multidisciplinary
Qing-Min Li, Gui-Shan Lin, Wen-Gui Duan, Yu-Cheng Cui, Fang-Yao Li, Fu-Hou Lei, Dian-Peng Li
Summary: Eighteen novel longifolene-derived tetralin pyrimidine compounds were designed and synthesized using survivin as the target. These compounds exhibited promising antiproliferative activities and low cytotoxicity towards normal liver cells. The study also established a 3D-QSAR model and conducted molecular docking to investigate the structure-activity relationship and interaction mode between compounds and survivin protein.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Vanessa Brito, Mariana Marques, Marta Esteves, Catarina Serra-Almeida, Gilberto Alves, Paulo Almeida, Liliana Bernardino, Samuel Silvestre
Summary: Novel 16E-arylidene-5 alpha,6 alpha-epoxyepiandrosterone derivatives were synthesized and evaluated for their cytotoxicity and neuroprotective activity. Some of these compounds showed selective cytotoxic effects in tumoral cell lines with evidence of apoptosis activation. However, they did not demonstrate significant neuroprotection against 6-OHDA-induced neurotoxicity. Molecular docking simulations predicted a strong affinity between these compounds and 5 alpha-reductase and 17 alpha-hydroxylase-17,20-lyase enzymes.
Article
Chemistry, Multidisciplinary
Ihab Shawish, Assem Barakat, Ali Aldalbahi, Azizah M. Malebari, Mohamed S. Nafie, Adnan A. Bekhit, Amgad Albohy, Alamgir Khan, Zaheer Ul-Haq, Matti Haukka, Beatriz G. de la Torre, Fernando Albericio, Ayman El-Faham
Summary: In this study, a series of novel 1,3,5-triazine derivatives were synthesized and their inhibitory activity against cancer cells was evaluated through in vitro assays. Among them, compound 4f showed significant antitumor activity and induced apoptosis by targeting EGFR and its downstream pathway.
Article
Biochemistry & Molecular Biology
Sonal Jaiswal, Sushanta K. Parida, Sandip Murarka, Priyanka Singh
Summary: The study identifies S-aryl dithiocarbamates as a potential class of anticancer drugs, which inhibit cancer cell proliferation, induce apoptosis, and exhibit microtubule-stabilizing properties.
BIOORGANIC & MEDICINAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Jinfeng Ding, Tiantian Sun, Hongmei Wu, Hongwei Zheng, Sijia Wang, Dezhi Wang, Wenpei Shan, Yong Ling, Yanan Zhang
Summary: A series of novel canthin-6-one (CO) derivatives (8a-l) were synthesized, and their water solubility, antiproliferative activity, and preliminary mechanism were investigated. Most compounds exhibited high cytotoxicity against human cancer cell lines, especially HT29 cells. The compound 8h with the N-methyl piperazine group showed the highest antiproliferative capability and could induce apoptosis, DNA damage, and ferroptosis. It represents a promising anticancer candidate.
Article
Chemistry, Applied
Swarna Kumari Gaja, Siva Bandi, Pavan Kumar Pavuluri, Shainy Sambyal, Vinod Kumar Jaina, H. M. Sampath Kumar, Sai Balaji Andugulapati, V Ramalingam, K. Suresh Babu
Summary: Piscidinol A (1) isolated from Aphanamixis polystachya showed modest anticancer activity. Analogues were synthesised and tested for their anticancer potential. Compounds 6e and 6i demonstrated significant anticancer activity against DU145 prostate cancer cells, inducing cell cycle arrest and late apoptosis.
NATURAL PRODUCT RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Katarzyna Piechowska, Angelika Baranowska-Laczkowska, Krzysztof Z. Laczkowski, Jolanta Konieczkowska, Mariola Siwy, Marharyta Vasylieva, Pawel Gnida, Pawel Nitschke, Ewa Schab-Balcerzak
Summary: The paper presents the synthesis and characterization of nine new thiazolyl-(phenyldiazenyl)-2H-chromen-2-one dyes, and investigates their electrochemical properties, photoisomerization process, and photovoltaic response. The synthesized azocoumarin derivatives exhibit reversible trans-cis isomerization and show promising photovoltaic activity.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Crystallography
Hessa H. H. Al-Rasheed, Sarah A. A. AL-khamis, Assem Barakat, Ayman El-Faham, Matti Haukka, Saied M. M. Soliman
Summary: A series of novel isatin-s-triazine hydrazone derivatives were synthesized and characterized. The synthetic method involved the reaction of s-triazine hydrazine precursors with isatin derivatives, which resulted in the formation of target products 6a-e with high yields and purities. The crystal structure analysis of compound 6c revealed the presence of significant non-covalent interactions.
Article
Biochemistry & Molecular Biology
Andrea Bistrovic Popov, Robert Vianelo, Petra Grbcic, Mirela Sedic, Sandra Kraljevic Pavelic, Kresimir Pavelic, Silvana Raic-Malic
Summary: Novel symmetrical bis-pyrrolo[2,3-d]pyrimidines and bis-purines and their monomers were synthesized and evaluated for antiproliferative activity in various cancer cells. Ultrasound irradiation in Cu(I)-catalyzed azide-alkyne cycloaddition was found to improve reaction efficiency and yield symmetric bis-heterocycles. A specific monomer showed strong growth inhibitory effects on pancreatic cancer cells, possibly through apoptosis induction. Further structural optimization is needed for developing effective and non-toxic agents against pancreatic cancer.
Article
Chemistry, Organic
Gildardo Rivera, Luca De Angelis, Ammar Al-Sayyed, Soumen Biswas, Hadi Arman, Michael P. Doyle
Summary: A convenient, efficient, and inexpensive method has been developed for the synthesis of 1,2,3-triazine derivatives via deoxygenation of 1,2,3-triazine 1-oxide using trialkyl phosphites. This method provides a range of aromatic and aliphatic substituted 1,2,3-triazine-4-carboxylate derivatives cleanly in high yields. Unexpected 1,2,4-triazine derivatives were also obtained as minor products.
Article
Environmental Sciences
Suguna Perumal, Raji Atchudan, Srinivasan Ramalingam, S. Aldawood, Natarajan Devarajan, Wonmok Lee, Yong Rok Lee
Summary: Graphene-silver nanoparticle and graphene-silver nanoparticle-polyvinylpyrrolidone composites were prepared and characterized. The composites exhibited broad-spectrum antibacterial potential, with graphene-silver nanoparticle-polyvinylpyrrolidone having the lowest minimum inhibitory concentration against Staphylococcus aureus. The composite material disrupted cell permeability, damaged cell walls, and caused cell death efficiently.
ENVIRONMENTAL RESEARCH
(2023)
Article
Chemistry, Analytical
Vasanth Magesh, Ashok K. K. Sundramoorthy, Dhanraj Ganapathy, Raji Atchudan, Sandeep Arya, Razan A. A. Alshgari, Ahmed Muteb Aljuwayid
Summary: In this study, an electrochemical transducer using MXene/Pd(OH)(2)/C composite was developed for the identification of nicotine levels in human sweat. The MXene/PHC composite demonstrated high sensitivity and selectivity towards nicotine oxidation. The sensor showed promising accuracy, sensitivity, selectivity, and stability for the quantification of nicotine in human sweat samples.
Review
Chemistry, Physical
Kamal Batcha Mohamed Ismail, Manoharan Arun Kumar, Shanmugam Mahalingam, Junghwan Kim, Raji Atchudan
Summary: Energy storage and conversion are crucial for renewable energy integration and energy optimization. Supercapacitors, particularly those using MoS2-based nanocomposites, are recognized for their high power density, long life cycles, low cost, and fast charging-discharging capability. The unique structure of MoS2 enables efficient ion transport and storage, making it a promising material for high-performance energy storage devices. This review article provides a comprehensive overview of the recent advancements, properties, and applications of MoS2 and its nanocomposites in supercapacitors, as well as highlighting future research directions and challenges.
Article
Polymer Science
Suguna Perumal, Raji Atchudan, Thomas Nesakumar Jebakumar Immanuel Edison, Sambasivam Sangaraju, Weslen Vedakumari Sathyaraj, Yong Rok Lee
Summary: A one-step hydrothermal-assisted carbonization process was used to prepare nitrogen/phosphorous-doped carbon dots from a water-soluble polymer, PMPC. The prepared P-CDs exhibited bright fluorescence, excellent photostability, excitation-dependent emission, and high quantum yield. They were explored as fluorescent ink for anti-counterfeiting and cellular multicolor imaging.
Review
Polymer Science
Weslen Vedakumari Sathyaraj, Lokesh Prabakaran, Jayavardhini Bhoopathy, Sankari Dharmalingam, Ramadoss Karthikeyan, Raji Atchudan
Summary: Diabetic wounds pose a serious health issue for individuals with diabetes, as they have a slow and improper healing process. Current diabetic wound dressings vary in their ability to absorb wound exudates and may cause maceration to surrounding tissues. This review focuses on the recent advances in polymeric biomaterial-based wound dressings and novel therapeutic regimes for diabetic wound treatment, highlighting the importance of developing dressings that can absorb exudates, promote gas exchange, protect against infections, and support the synthesis of crucial biochemical factors for faster wound healing. The use of polymeric wound dressings loaded with bioactive compounds and their in vitro and in vivo performance in treating diabetic wounds are also discussed.
Article
Chemistry, Physical
Raji Atchudan, Suguna Perumal, Thomas Nesakumar Jebakumar Immanuel Edison, Ashok K. Sundramoorthy, Namachivayam Karthik, Sambasivam Sangaraju, Seung Tae Choi, Yong Rok Lee
Summary: Heteroatom-doped porous carbon material (H-PCM) was synthesized from cashew nut's skin through a simple pyrolysis route. The synthesized H-PCM exhibited a porous structure with sponge-like and sheet-like morphology, as well as a moderate degree of graphitization/crystallinity and various functionalities. The as-prepared H-PCM showed excellent electrocatalytic activity for hydrogen evolution reaction (HER) in 0.5 M H2SO4 aqueous solution, making it a promising candidate for metal-free carbonaceous catalysts in large-scale hydrogen production through electrochemical water splitting.
Article
Chemistry, Physical
Somasundaram Chandra Kishore, Suguna Perumal, Raji Atchudan, Thomas Nesakumar Jebakumar Immanuel Edison, Ashok K. Sundramoorthy, Muthulakshmi Alagan, Sambasivam Sangaraju, Yong Rok Lee
Summary: In this study, functionalized carbon nanodots (F-CNDs) were synthesized from cashew nut skin waste using a hydrothermal method. The F-CNDs exhibited excellent dispersion, hydrophilicity, and biocompatibility. These findings suggest that the F-CNDs may have potential applications in the field of biomedicine.
Article
Chemistry, Multidisciplinary
Raji Atchudan, Suguna Perumal, Ashok K. Sundramoorthy, Devaraj Manoj, Raju Suresh Kumar, Abdulrahman I. Almansour, Yong Rok Lee
Summary: Nitrogen, oxygen, and sulfur co-doped porous carbon materials were prepared by direct pyrolysis of Anacardium occidentale nut-skin waste for high-performance supercapacitors. These materials exhibited high specific surface area, moderate degree of graphitization, and delivered excellent electrochemical performance and cycling stability. Therefore, the use of waste biomass materials for supercapacitor fabrication through a simple pyrolysis route provides a cost-effective and environmentally friendly strategy.
Article
Crystallography
Gokul Sridharan, Kaushik L. Babu, Dhanraj Ganapathy, Raji Atchudan, Sandeep Arya, Ashok K. Sundramoorthy
Summary: In this study, Phyllanthus Reticulatus fruit extract was used as a reducing agent to synthesize silver nanoparticles (Ag-NPs) for the first time. Various methods were employed to analyze the samples, revealing that the synthesized Ag-NPs had a spherical shape and uniform size. XRD and UV-VIS analysis confirmed the crystal structure and optical energy absorption spectrum of the Ag-NPs. This new method provides a simple and eco-friendly approach to produce silver and other noble metals in large quantities. Additionally, the Ag-NPs modified glassy carbon electrode showed enhanced electron transfer rate and good electrocatalytic performance for nicotine oxidation.
Article
Materials Science, Multidisciplinary
Radhika Rajendhiran, Raji Atchudan, Jayabal Palanisamy, Athinarayanan Balasankar, Tae Hwan Oh, Venugopal Deivasigamani, Subramaniyan Ramasundaram
Summary: Plant extracts, such as prickly pear fruit extract (PPE), can be used as ecofriendly natural reducing agents for the synthesis of metal oxide nanomaterials. PPE was used to synthesize titanium dioxide nanoparticles (TiO2 NPs) and as a sensitizer for dye-sensitized solar cells (DSSCs). The use of PPE resulted in discrete TiO2 NPs and increased power-conversion efficiency for DSSCs.
Review
Chemistry, Analytical
Rubiya Raveendran, Lokesh Prabakaran, Rethinam Senthil, Beryl Vedha Yesudhason, Sankari Dharmalingam, Weslen Vedakumari Sathyaraj, Raji Atchudan
Summary: Biosensors are devices used for quantifying biologically significant information in various applications, such as disease diagnosis and environmental pollutant detection. Recent advancements in microfluidics, nanotechnology, and electronics have led to the development of implantable and wearable biosensors for the monitoring of diseases like diabetes, glaucoma, and cancer. This review focuses on the use of nanotechnology in detecting and treating glaucoma and continuous monitoring of intraocular pressure (IOP), discussing achievements such as nanoparticle/nanofiber-based contact lenses and biosensors for efficient glaucoma detection.
Review
Biochemistry & Molecular Biology
Somasundaram Chandra Kishore, Suguna Perumal, Raji Atchudan, Muthulakshmi Alagan, Mohammad Ahmad Wadaan, Almohannad Baabbad, Devaraj Manoj
Summary: Hydrogen energy is converted to electricity through fuel cells with the help of nanostructured materials. Despite its potential, fuel cell technology still faces challenges such as high cost and durability issues. Nanomaterials can address these drawbacks by enhancing catalysts, electrodes, and fuel cell membranes.
Article
Chemistry, Analytical
Vasanth Magesh, Vishaka S. Kothari, Dhanraj Ganapathy, Raji Atchudan, Sandeep Arya, Deepak Nallaswamy, Ashok K. Sundramoorthy
Summary: This study developed an electrochemical sensor for the determination of ethanol in human salivary samples. The sensor, modified with sparfloxacin-stabilized gold nanoparticles, showed enhanced electrocatalytic activity and sensitivity for ethanol oxidation. The sensor demonstrated high stability and sensitivity, and successfully determined ethanol in saliva samples with a recovery rate of 99.6%.
Article
Chemistry, Analytical
Kavitha Kamalasekaran, Vasanth Magesh, Raji Atchudan, Sandeep Arya, Ashok K. Sundramoorthy
Summary: In this study, a precise and sensitive electrochemical sensor for nicotine detection in saliva samples was developed. The sensor exhibited excellent selectivity and sensitivity, and showed good detection performance in the presence of common interfering molecules.
Article
Chemistry, Physical
Kamatam Hari Prasad, S. Vinoth, V. Ganesh, Ramesh Ade
Summary: Different concentrations of indium (In)-doped MoO3 thin films were synthesized using nebulizer spray pyrolysis method for room temperature ammonia gas sensing. The prepared 3% In-doped MoO3 film exhibited the highest gas response for NH3 detection at ambient temperature, along with faster response and recovery times.
Article
Chemistry, Multidisciplinary
Zihan Ma, Lishuang Wang, Tingting Chen, Guangning Wang
Summary: In this study, two kinds of 3D self-doped (N/O) lilac-based and coriander-based porous carbons with high performance have been prepared.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Qin Wang, Yun-Fan Yan, Jiao-Lin Weng, Ying Huang, Fu Yang, Hao-Hui Xie, Fei Tan, Fa-Kun Zheng, Jian-Gang Xu
Summary: Balancing energy and mechanical sensitivities is a challenging issue in the field of energetic materials. This study constructed a 3D energetic metal-organic framework with nitrogen-rich ligand and NO3- anions. The framework demonstrated high stability, energy density, and excellent mechanical sensitivities, making it a potential insensitive energetic material.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Marrium Saeed, Urooj Kamran, Amina Khan, Md Irfanul Haque Siddiqui, Hasan Jamal, Haq Nawaz Bhatti
Summary: In this study, magnesium-aluminum layered double hydroxides (Mg-Al-LDH) were synthesized using an environmentally friendly hydrothermal technique for adsorbing the dye reactive green 5 (RG5). To improve the adsorption capability, composites were prepared by combining Mg-Al-LDH with low-cost Mangifera indica stone biomass (MISB). The results showed that the composites had high adsorption capacities for RG5 dye and could be regenerated.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Xuanlin Zhan, Xiaojie Li, Yunyan Zeng, Siyan Jiang, Chao Pan, Shiyu Pan, Jiaquan Huang, Heqian Zhang, Zhiwei Qin
Summary: This study reports on the potential prospects of natural products derived from the rhizosphere for the development of antibiotics and herbicides, as well as the advancements in cultivating a mutant strain that produces a substantial quantity of lydicamycins, a potent family for herbicide development.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Jie Zhu, Jiangtao Yu, Linhua Zhu, Xiaoxiao Yu, Jixing Liu, Yanhong Chao, Jingzhou Yin, Peiwen Wu, Jian Liu, Wenshuai Zhu
Summary: This study successfully demonstrates the 3D printing of attapulgite monoliths and investigates the influence of thermal treatment on their properties. The thermal treated monoliths show superior catalytic performance at low temperatures.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Yanzhu Ye, Yixiang Ye, Jiannan Cai, Zhongshui Li, Shen Lin
Summary: In this paper, a novel Pt/CoP/C photo-electro synergistic catalyst was successfully synthesized and its performance was investigated. The catalyst exhibited excellent photo-electro catalytic performance, with significantly higher hydrogen production compared to a commercial catalyst. The introduction of cobalt phosphide and the existence of Co3O4 were identified as key factors for enhancing the catalytic activity.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Nurul Hidayah Abu Bakar, Wan Norfazilah Wan Ismail, Hartina Mohd Yusop, Noreen Farzuhana Mohd Zulkifli
Summary: Hydrophobic coatings inspired by the lotus effect have gained popularity for their ability to solve various problems. The sol-gel method, utilizing silica, alumina, and titania, is explored as an environmentally friendly approach to produce water-based hydrophobic coatings. This study focuses on producing water-based hydrophobic coatings for cotton and polyester fabrics using a one-step sol-gel method. The coated fabrics exhibited improved hydrophobic properties, altered surface morphologies, and lower air permeability compared to uncoated fabrics. TEOS-PDMS coating provides a promising approach for enhancing the hydrophobic and surface properties of cotton and polyester fabrics.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Nikita Belko, Hanna Maltanava, Anatol Lugovski, Polina Shabunya, Sviatlana Fatykhava, Evgeny Bondarenko, Pavel Chulkin, Sergey Poznyak, Michael Samtsov
Summary: This study investigates the difference in electrochemical behavior between rhodamine B hydrazide and rhodamine B acylhydrazone, and finds that rhodamine B acylhydrazone exhibits higher reversibility in electrooxidation. These results can be applied for developing new sensors with desired electrochemical properties.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Showket Ahmad Bhat, Mohd Ikram
Summary: In this study, 0-3 particulate multiferroic composites were synthesized and characterized. The composites exhibited excellent ferroelectric and ferromagnetic properties, as well as high piezoelectric strain and magnetoelectric coupling effects.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Carla Gomes, Mariana Costa, Susana M. M. Lopes, Bernardo Albuquerque Nogueira, Rui Fausto, Jose A. Paixao, Teresa M. V. D. e Melo, Luisa M. D. R. S. Martins, Marta Pineiro
Summary: The development of sustainable processes requires the integration of green chemistry principles. In this study, a solvent-free synthesis method was developed to prepare new copper catalysts, which efficiently catalyze cycloaddition reactions under solvent-free mechanochemical conditions. Through this process, the principles of atom economy, reduction of solvents and auxiliaries, design for energy efficiency, and reduction of derivatives and catalysis are combined.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Zhihua Liu, Jinzhe Li, Jianguo Zhou
Summary: This study demonstrates the enhancement of photoelectrochemical activity of BiFeO3 photoelectrodes through ion modification, which increases visible light absorption and active area, leading to improved PEC water splitting performance.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Yisheng Zhang, Wensong Li, Jing Li, Fang Li, Wei Xue, Xinqiang Zhao, Yanji Wang
Summary: Pt/C and SO42-/ZrO2 were used as catalysts for the synthesis of p-aminophenol through the catalytic transfer hydrogenation of nitrobenzene in water with formic acid as the hydrogen source. The optimal Pt loading for PAP selectivity was found to be 1 wt%. The presence of different valence states of Pt affected both the nitrobenzene hydrogenation and formic acid decomposition. Among different solid acid catalysts tested, SO42-/ZrO2 exhibited the highest catalytic activity for p-aminophenol formation. Under the optimized reaction conditions, the conversion of nitrobenzene reached 80.0%, with a selectivity of 47.6% for p-aminophenol.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Pradyota Kumar Behera, Papita Behera, Amlan Swain, Santosh Kumar Sahu, Ajeena Sahoo, Laxmidhar Rout
Summary: We have developed a simple and direct method for the synthesis of diaryl ether using an oxygen bridged bimetallic CuMoO4 nanocatalyst under mild reaction conditions. The catalyst exhibited tolerance towards a wide range of substrates with various functional groups. It is efficient and recyclable. This methodology allows easy access to nitrofen derivatives (herbicides) from unactivated 2,4-dichlorophenol, which are important for agriculture and pharmaceuticals.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Yihua Fu, Yan Zhang, Changwei Hu, Zhishan Su
Summary: The mechanism of the reaction between CO2 and styrene oxide for cyclic carbonate was revealed using density functional theory calculations. The noncatalytic reaction occurred via a concerted mechanism, while in the presence of guanidine and tetrabutylammonium iodide (TBAI) co-catalysts, the epoxide ring-opening by nucleophilic attack of an iodide anion was predicted to be the rate-determining step. Guanidine acted as the H-bond donor to activate styrene oxide, facilitating the reaction with a lower activation barrier.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Saikat Khamarui, Sirshendu Ghosh
Summary: Copper nanorods (Cu-NRs) exhibit significant plasmonic behavior and can act as efficient catalysts in redox processes and coupling. A benign decarboxylative approach, utilizing localized surface plasmon resonance (LSPR) assisted catalysis with Cu-NRs, has been developed for the production of alkane analogues from alkyl carboxylic acids under visible light. The catalyst shows a broad substrate scope and high functional group tolerance, without the need for an external oxidant or proton source. A plausible mechanism for this recyclable nano-catalyst has also been proposed based on control experiments.
NEW JOURNAL OF CHEMISTRY
(2024)
