Targeted 5-HT1F Therapies for Migraine

Lasmiditan for the treatment of migraine

(2017) Matilde Capi et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Serotonin receptor targeted therapy for migraine treatment: an overview of drugs in phase I and II clinical development

(2017) Piero Barbanti et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

The safety and efficacy of the 5-HT 1F receptor agonist lasmiditan in the acute treatment of migraine

(2017) Bianca Raffaelli et al.   EXPERT OPINION ON PHARMACOTHERAPY

Triptans and migraine: advances in use, administration, formulation, and development

(2017) Amanda E. Macone et al.   EXPERT OPINION ON PHARMACOTHERAPY

An Update on Non-Pharmacological Neuromodulation for the Acute and Preventive Treatment of Migraine

(2017) Francesca Puledda et al.   HEADACHE

Current and novel insights into the neurophysiology of migraine and its implications for therapeutics

(2017) Simon Akerman et al.   PHARMACOLOGY & THERAPEUTICS

Pathophysiology of Migraine: A Disorder of Sensory Processing

(2017) Peter J. Goadsby et al.   PHYSIOLOGICAL REVIEWS

Headache research in 2015: progress in migraine treatment

(2016) Hans-Christoph Diener et al.   LANCET NEUROLOGY

Emerging therapeutic options for acute migraine: focus on the potential of lasmiditan

(2014) Paul Rizzoli   Neuropsychiatric Disease and Treatment

The pharmacological profile and clinical prospects of the oral 5-HT1F receptor agonist lasmiditan in the acute treatment of migraine

(2014) Uwe Reuter et al.   Therapeutic Advances in Neurological Disorders

The International Classification of Headache Disorders, 3rd edition (beta version)

(2013)   CEPHALALGIA

Drugs targeting 5-hydroxytryptamine receptors in acute treatments of migraine attacks. A review of new drugs and new administration forms of established drugs

(2013) Peer C Tfelt-Hansen et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Activation of 5-hydroxytryptamine1B/1D/1Freceptors as a mechanism of action of antimigraine drugs

(2013) Martha B Ramírez Rosas et al.   EXPERT OPINION ON PHARMACOTHERAPY

Dihydroergotamine, Ergotamine, Methysergide and Sumatriptan - Basic Science in Relation to Migraine Treatment

(2012) Carl Dahlöf et al.   HEADACHE

The 5-HT1F receptor agonist lasmiditan as a potential treatment of migraine attacks: a review of two placebo-controlled phase II trials

(2012) Peer C. Tfelt-Hansen et al.   JOURNAL OF HEADACHE AND PAIN

Efficacy and tolerability of lasmiditan, an oral 5-HT1F receptor agonist, for the acute treatment of migraine: a phase 2 randomised, placebo-controlled, parallel-group, dose-ranging study

(2012) Markus Färkkilä et al.   LANCET NEUROLOGY

mRNA expression of 5-hydroxytryptamine 1B, 1D, and 1F receptors and their role in controlling the release of calcitonin gene–related peptide in the rat trigeminovascular system

(2012) Dipak V. Amrutkar et al.   PAIN

Distribution of 5-HT 1B , 5-HT 1D and 5-HT 1F receptor expression in rat trigeminal and dorsal root ganglia neurons: Relevance to the selective anti-migraine effect of triptans

(2010) J.D. Classey et al.   BRAIN RESEARCH

5-Hydroxyptryptamine 1F (5-HT1F) receptor agonism. A possible new treatment principle for acute migraine attacks

(2010) Jes Olesen   CEPHALALGIA

Preclinical pharmacological profile of the selective 5-HT1F receptor agonist lasmiditan

(2010) David L Nelson et al.   CEPHALALGIA

Acute treatment of migraine with the selective 5-HT1F receptor agonist lasmiditan – A randomised proof-of-concept trial

(2010) Michel D Ferrari et al.   CEPHALALGIA

Colocalization of 5-HT1F receptor and glutamate in neurons of the vestibular nuclei in rats

(2009) Seong-Ki Ahn et al.   NEUROREPORT

Colocalization of 5-HT1F receptor and calcitonin gene-related peptide in rat vestibular nuclei

(2009) Seong-Ki Ahn et al.   NEUROSCIENCE LETTERS

The vascular theory of migraine—a great story wrecked by the facts

(2008) Peter J. Goadsby   BRAIN

History of Methysergide in Migraine

(2008) PJ Koehler et al.   CEPHALALGIA

History of the Use of Ergotamine and Dihydroergotamine in Migraine From 1906 and Onward

(2008) PC Tfelt-Hansen et al.   CEPHALALGIA

Sumatriptan Inhibits Synaptic Transmission in the Rat Midbrain Periaqueductal Grey

(2008) Hyo-Jin Jeong et al.   Molecular Pain