ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism

Published 2018 View Full Article

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Title
ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism
Authors
Keywords
ATXN1, CIC, neurodegeneration, ataxia, cerebellum, toxicity, polyglutamine, RAN translation, RNA toxicity
Journal
NEURON
Volume 97, Issue 6, Pages 1235-1243.e5
Publisher
Elsevier BV
Online
2018-03-09
DOI
10.1016/j.neuron.2018.02.013

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