Article
Immunology
Johnna R. Swartz, Angelica F. Carranza, Laura M. Tully, Annchen R. Knodt, Janina Jiang, Michael R. Irwin, Camelia E. Hostinar
Summary: The study found associations between peripheral inflammation and adolescent brain connectivity, with higher TNF-α levels linked to changes in neural network connections. Associations with IL-6 and CRP were not significant, suggesting that inflammation may have unique effects on brain connectivity during adolescence.
BRAIN BEHAVIOR AND IMMUNITY
(2021)
Article
Behavioral Sciences
Leehyun Yoon, Angelica F. Carranza, Johnna R. Swartz
Summary: This study examines the association between personality dimensions and brain functional connectivity in adolescents, specifically focusing on extraversion and agreeableness. The results reveal sex-specific neural connectivity patterns associated with these personality dimensions and suggest that intrinsic functional connectivity contributes to individual differences in extraversion and agreeableness in adolescents.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE
(2022)
Article
Neurosciences
David E. Warren, Anthony J. Rangel, Nicholas J. Christopher-Hayes, Jacob A. Eastman, Michaela R. Frenzel, Julia M. Stephen, Vince D. Calhoun, Yu-Ping Wang, Tony W. Wilson
Summary: The study examined the hippocampal rs-FC in healthy children before adolescence, finding associations between hippocampal rs-FC, brain networks, age, and hippocampal-dependent memory, but not with working memory. These findings contribute to our understanding of neural development and cognitive development theories.
HUMAN BRAIN MAPPING
(2021)
Article
Neurosciences
Xin Hao, Taicheng Huang, Yiying Song, Xiangzhen Kong, Jia Liu
Summary: The study reveals age-related changes in the navigation network organization, with increasing modularity under resting-state and increasing flexibility under task-state. Task-modulated FC changes were found to be greater in adults than in children, suggesting differences in network organization between age groups during tasks.
Article
Neurosciences
Limin Peng, Zhiguo Luo, Ling-Li Zeng, Chenping Hou, Hui Shen, Zongtan Zhou, Dewen Hu
Summary: This study developed a brain parcellation method based on dynamic functional connectivity and created a new functional brain atlas. The atlas can reveal finer functional boundaries that static methods may overlook, and shows good agreement with cytoarchitectonic areas and task activation maps.
Article
Multidisciplinary Sciences
Ning Yang, Shuyi Yuan, Chunlong Li, Wenqing Xiao, Shuangcong Xie, Liming Li, Guihua Jiang, Xiaofen Ma
Summary: This study investigated the potential of using amplitude of low-frequency fluctuation (ALFF) and functional connectivity (FC) features as neurological markers for identifying chronic insomnia (CI). The results showed significant differences in ALFF and FC features between CI patients and healthy controls, and these features were correlated with clinical characteristics. This suggests that ALFF and FC may serve as potential neuromarkers for diagnosing CI.
SCIENTIFIC REPORTS
(2023)
Article
Psychiatry
Hanie Edalati, Mohammad H. Afzali, Sean Spinney, Josiane Bourque, Alain Dagher, Patricia J. Conrod
Summary: This study found that peer victimization during adolescence is associated with changes in neural responses in regions responsible for emotional regulation and an increased risk of psychopathology. The study also demonstrated the mediating effects of resting-state functional connectivity between adolescent peer victimization and subsequent internalizing symptoms. These findings have important implications for interventions targeting internalizing symptoms in victimized adolescents.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Clinical Neurology
Yuqi Cai, Nourhan M. Elsayed, Deanna M. Barch
Summary: Family history of Major Depressive Disorder (MDD) is a strong predictor of MDD onset in early adolescence. Negative wDMN rsFC is associated with current depression in children and current depressive symptoms in parents. Familial risk for depression interacts with wDMN rsFC in association with past MDD diagnosis in children and current depressive symptoms in parents.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Neurosciences
Anees Abrol, Zening Fu, Yuhui Du, Tony W. W. Wilson, Yu-Ping Wang, Julia M. M. Stephen, Vince D. D. Calhoun
Summary: The brain's functional architecture and organization undergo continuous development and modification throughout adolescence. This study systematically evaluated over 47,000 youth and adult brains to examine time-resolved functional connectivity patterns and found distinct differences between the two life stages, indicating an overall inverted U-shaped trajectory in the strengthening and modularization of functional coupling. These findings suggest greater synchrony and integration of the brain's functional connections beyond adolescence, with a gradual decline during healthy aging.
HUMAN BRAIN MAPPING
(2023)
Article
Clinical Neurology
Divyangana Rakesh, Jinglei Lv, Andrew Zalesky, Nicholas B. Allen, Dan Lubman, Murat Yucel, Sarah Whittle
Summary: The study identified different neural circuits between adolescent SUD and problematic substance use, with greater negative coupling in problematic substance users possibly indicating a risk for future development of SUD or other mental health problems. Furthermore, hypoconnectivity within the insula in adolescents with SUD may suggest addiction-related alterations in interoceptive awareness or impairments in decision-making.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Psychology, Clinical
Lizhu Luo, Christelle Langley, Laura Moreno-Lopez, Keith Kendrick, David K. Menon, Emmanuel A. Stamatakis, Barbara J. Sahakian
Summary: This study examined the association between depressive symptoms in traumatic brain injury (TBI) patients and altered resting-state functional connectivity (rs-fc) or voxel-based morphology in brain regions involved in emotional regulation and associated with depression. The results showed a positive association between depression scores and rs-fc between limbic regions and cognitive control regions, while there was a negative association between depression scores and rs-fc between limbic and frontal regions involved in emotion regulation. These findings contribute to a better understanding of the mechanisms underlying depression following TBI and can inform treatment decisions.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Neurosciences
Serafeim Loukas, Lara Lordier, Djalel-Eddine Meskaldji, Manuela Filippa, Joana Sa de Almeida, Dimitri Van de Ville, Petra S. Hueppi
Summary: Research indicates that even during the newborn period, familiar music and unfamiliar music are processed differently by the brain. After music listening, functional connectivity between brain regions in all newborns is modulated. Premature infants exposed to music experience enhanced functional connectivity between brain regions after listening to music.
HUMAN BRAIN MAPPING
(2022)
Article
Psychology, Multidisciplinary
Emil Holmer, Krister Schonstrom, Josefine Andin
Summary: This study investigates the associations between linguistic skills in sign language and resting-state functional connectivity (rsFC). The results show that worse sentence processing skill is associated with stronger positive rsFC between the left inferior frontal gyrus (IFG) and left sensorimotor regions. Additionally, sign language phonological processing skill is associated with positive rsFC from right IFG to middle frontal gyrus/frontal pole, although this association could possibly be explained by domain-general cognitive functions.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Neurosciences
Ke Song, Yong Wang, Mei-Xia Ren, Jiao Li, Ting Su, Si-Yi Chen, Yi Shao, Ya-Li Lv
Summary: Using resting-state functional connectivity, this study found abnormal neural activities in specific brain regions of patients with optic neuritis, with significant changes in rsFC, longFCD, and IFCD values, which may help identify the specific mechanism of change in brain function in ON.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Neurosciences
Dorine Van Dyck, Nicolas Deconinck, Alec Aeby, Simon Baijot, Nicolas Coquelet, Nicola Trotta, Antonin Rovai, Serge Goldman, Charline Urbain, Vincent Wens, Xavier De Tiege
Summary: This study explores the relationship between procedural sequence learning performance and prior brain resting-state functional connectivity (rsFC) in school-aged children. It also investigates the rapid changes in brain rsFC induced by sequence learning. The findings suggest that pre-learning interhemispheric rsFC within the sensorimotor network influences sequence learning and visuomotor performance in children.
Article
Neurosciences
Jose Sanchez-Bornot, Roberto C. Sotero, J. A. Scott Kelso, Ozguer Simsek, Damien Coyle
Summary: This study proposes a multi-penalized state-space model for analyzing unobserved dynamics, using a data-driven regularization method. Novel algorithms are developed to solve the model, and a cross-validation method is introduced to evaluate regularization parameters. The effectiveness of this method is validated through simulations and real data analysis, enabling a more accurate exploration of cognitive brain functions.