A Docosahexaenoic Acid-Derived Pro-resolving Agent, Maresin 1, Protects Motor Neuron Cells Death

Modulation of central endocannabinoid system results in gastric mucosal protection in the rat

(2018) V.E. Tóth et al.   BRAIN RESEARCH BULLETIN

Edaravone is a candidate agent for spinal muscular atrophy: In vitro analysis using a human induced pluripotent stem cells-derived disease model

(2017) Shiori Ando et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Roxatidine attenuates mast cell-mediated allergic inflammation via inhibition of NF-κB and p38 MAPK activation

(2017) Minho Lee et al.   Scientific Reports

The pro-resolving lipid mediator Maresin 1 protects against cerebral ischemia/reperfusion injury by attenuating the pro-inflammatory response

(2016) Wenjing Xian et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Th17 Cell Response inSOD1G93AMice following Motor Nerve Injury

(2016) Allen Ni et al.   MEDIATORS OF INFLAMMATION

Maresin 1, a Proresolving Lipid Mediator, Mitigates Carbon Tetrachloride-Induced Liver Injury in Mice

(2016) Ruidong Li et al.   Oxidative Medicine and Cellular Longevity

Genome-wide RNA-Seq of Human Motor Neurons Implicates Selective ER Stress Activation in Spinal Muscular Atrophy

(2015) Shi-Yan Ng et al.   Cell Stem Cell

Oxr1 improves pathogenic cellular features of ALS-associated FUS and TDP-43 mutations

(2015) M. J. Finelli et al.   HUMAN MOLECULAR GENETICS

Astrocytes influence the severity of spinal muscular atrophy

(2015) Hansjörg Rindt et al.   HUMAN MOLECULAR GENETICS

Activation of ER Stress and Autophagy Induced by TDP-43 A315T as Pathogenic Mechanism and the Corresponding Histological Changes in Skin as Potential Biomarker for ALS with the Mutation

(2015) Xuejing Wang et al.   International Journal of Biological Sciences

MARESIN 1 PREVENTS LIPOPOLYSACCHARIDE-INDUCED NEUTROPHIL SURVIVAL AND ACCELERATES RESOLUTION OF ACUTE LUNG INJURY

(2015) Jie Gong et al.   SHOCK

Maresin-1 reduces airway inflammation associated with acute and repetitive exposures to organic dust

(2015) Tara M. Nordgren et al.   Translational Research

Inflammation Induces TDP-43 Mislocalization and Aggregation

(2015) Ana Sofia Correia et al.   PLoS One

Endoplasmic reticulum stress triggers ROS signalling, changes the redox state, and regulates the antioxidant defence of Arabidopsis thaliana

(2014) Rengin Ozgur et al.   JOURNAL OF EXPERIMENTAL BOTANY

Axonal Transport of TDP-43 mRNA Granules Is Impaired by ALS-Causing Mutations

(2014) Nael H. Alami et al.   NEURON

SOD1 Function and Its Implications for Amyotrophic Lateral Sclerosis Pathology

(2014) Rosie K. A. Bunton-Stasyshyn et al.   NEUROSCIENTIST

Metabotyping of Docosahexaenoic Acid - Treated Alzheimer’s Disease Cell Model

(2014) Priti Bahety et al.   PLoS One

Chemokine Receptor CCR8 Is Required for Lipopolysaccharide-Triggered Cytokine Production in Mouse Peritoneal Macrophages

(2014) Tomoyuki Oshio et al.   PLoS One

Astrocytes expressing mutant SOD1 and TDP43 trigger motoneuron death that is mediated via sodium channels and nitroxidative stress

(2014) Fabiola Rojas et al.   Frontiers in Cellular Neuroscience

ω-3 Fatty Acid Supplementation as a Potential Therapeutic Aid for the Recovery from Mild Traumatic Brain Injury/Concussion

(2014) Erin Cernkovich Barrett et al.   Advances in Nutrition

Dietary ω-3 Polyunsaturated Fatty Acid Intake and Risk for Amyotrophic Lateral Sclerosis

(2014) Kathryn C. Fitzgerald et al.   JAMA Neurology

Maresin 1, a Proresolving Lipid Mediator Derived from Omega-3 Polyunsaturated Fatty Acids, Exerts Protective Actions in Murine Models of Colitis

(2013) R. Marcon et al.   JOURNAL OF IMMUNOLOGY

SA4503, a sigma-1 receptor agonist, suppresses motor neuron damage in in vitro and in vivo amyotrophic lateral sclerosis models

(2013) Yoko Ono et al.   NEUROSCIENCE LETTERS

The Omega-3 Fatty Acid Eicosapentaenoic Acid Accelerates Disease Progression in a Model of Amyotrophic Lateral Sclerosis

(2013) Ping K. Yip et al.   PLoS One

Early pathogenesis in the adult-onset neurodegenerative disease amyotrophic lateral sclerosis

(2012) Brigitte van Zundert et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

ER Stress Activates NF-κB by Integrating Functions of Basal IKK Activity, IRE1 and PERK

(2012) Arvin B. Tam et al.   PLoS One

Wild-type and A315T mutant TDP-43 exert differential neurotoxicity in a Drosophila model of ALS

(2011) Patricia S. Estes et al.   HUMAN MOLECULAR GENETICS

An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity

(2011) Weirui Guo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Docosahexaenoic Acid-Derived Neuroprotectin D1 Induces Neuronal Survival via Secretase- and PPARγ-Mediated Mechanisms in Alzheimer's Disease Models

(2011) Yuhai Zhao et al.   PLoS One

Crosstalk of reactive oxygen species and NF-κB signaling

(2010) Michael J Morgan et al.   CELL RESEARCH

Constitutively active NF- B triggers systemic TNF -dependent inflammation and localized TNF -independent inflammatory disease

(2010) J. Dong et al.   GENES & DEVELOPMENT

Aggregation of Copper–Zinc Superoxide Dismutase in Familial and Sporadic ALS

(2009) Madhuri Chattopadhyay et al.   ANTIOXIDANTS & REDOX SIGNALING

Omega-3 PUFA derived anti-inflammatory lipid mediator resolvin E1

(2009) Hiroyuki Seki et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

TDP-43A315T mutation in familial motor neuron disease

(2008) Michael A. Gitcho et al.   ANNALS OF NEUROLOGY

Expression of Amyotrophic Lateral Sclerosis-linked SOD1 Mutant Increases the Neurotoxic Potential of Microglia via TLR2

(2008) Yang Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions

(2008) Charles N. Serhan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neuroglobin protects PC12 cells against oxidative stress

(2007) Richard C. Li et al.   BRAIN RESEARCH