Impaired Cu–Zn Superoxide Dismutase (SOD1) and Calcineurin (Cn) Interaction in ALS: A Presumed Consequence for TDP-43 and Zinc Aggregation in Tg SOD1G93A Rodent Spinal Cord Tissue

The Role of Metal Binding in the Amyotrophic Lateral Sclerosis-Related Aggregation of Copper-Zinc Superoxide Dismutase

(2017) et al.   MOLECULES

The phosphatase calcineurin regulates pathological TDP-43 phosphorylation

(2016) Nicole F. Liachko et al.   ACTA NEUROPATHOLOGICA

Destabilization of the metal site as a hub for the pathogenic mechanism of five ALS-linked mutants of copper, zinc superoxide dismutase

(2016) Raúl Mera-Adasme et al.   Metallomics

A New Phase in ALS Research

(2016) P. Andrew Chong et al.   STRUCTURE

The Disulfide Bond, but Not Zinc or Dimerization, Controls Initiation and Seeded Growth in Amyotrophic Lateral Sclerosis-linked Cu,Zn Superoxide Dismutase (SOD1) Fibrillation

(2015) Madhuri Chattopadhyay et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aberrant zinc binding to immature conformers of metal-free copper–zinc superoxide dismutase triggers amorphous aggregation

(2015) Sónia S. Leal et al.   Metallomics

Recent progress in the discovery of small molecules for the treatment of amyotrophic lateral sclerosis (ALS)

(2013) Allison S Limpert et al.   Beilstein Journal of Organic Chemistry

Cupric Ions Induce the Oxidation and Trigger the Aggregation of Human Superoxide Dismutase 1

(2013) Cheng Li et al.   PLoS One

Regulation of RCAN1 translation and its role in oxidative stress-induced apoptosis

(2012) Yili Wu et al.   FASEB JOURNAL

TDP-43 and FUS/TLS: cellular functions and implications for neurodegeneration

(2011) Fabienne C. Fiesel et al.   FEBS Journal

Phosphorylation Promotes Neurotoxicity in a Caenorhabditis elegans Model of TDP-43 Proteinopathy

(2010) N. F. Liachko et al.   JOURNAL OF NEUROSCIENCE

TAR DNA-binding protein 43 in neurodegenerative disease

(2010) Alice S. Chen-Plotkin et al.   Nature Reviews Neurology

TDP-43-Based Animal Models of Neurodegeneration: New Insights into ALS Pathology and Pathophysiology

(2010) Iga Wegorzewska et al.   Neurodegenerative Diseases

Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies

(2009) Manuela Neumann et al.   ACTA NEUROPATHOLOGICA

A Role for Copper in the Toxicity of Zinc-Deficient Superoxide Dismutase to Motor Neurons in Amyotrophic Lateral Sclerosis

(2009) Kari A. Trumbull et al.   ANTIOXIDANTS & REDOX SIGNALING

The ALS-Associated Mutation G93A in Human Copper-Zinc Superoxide Dismutase Selectively Destabilizes the Remote Metal Binding Region

(2009) Anna Katrine Museth et al.   BIOCHEMISTRY

Non–cell autonomous toxicity in neurodegenerative disorders: ALS and beyond

(2009) Hristelina Ilieva et al.   JOURNAL OF CELL BIOLOGY

Accumulation of labile zinc in neurons and astrocytes in the spinal cords of G93A SOD-1 transgenic mice

(2009) Jean Kim et al.   NEUROBIOLOGY OF DISEASE

Structures of the G85R Variant of SOD1 in Familial Amyotrophic Lateral Sclerosis

(2008) Xiaohang Cao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of zinc exposure on HNE and GLT-1 in spinal cord culture

(2008) Xiaomei Yao   NEUROTOXICOLOGY