Letter
Medicine, General & Internal
Vikram Fielding-Singh, Matthew W. Vanneman, Arden M. Morris, Glenn M. Chertow, Eugene Lin
Summary: This cohort study examines the relationship between patient characteristics and the time interval between hemodialysis and surgery in end-stage kidney disease patients.
Review
Pharmacology & Pharmacy
Yinghui Wang, Lu Gao
Summary: Chronic kidney disease and cardiac insufficiency often co-exist, especially in uremic patients on hemodialysis. Impaired renal function is often indicative of poor prognosis in patients with cardiac insufficiency. Inflammation plays a significant role in the development of cardiovascular complications in patients with chronic kidney disease and is indicative of prognosis.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Medicine, General & Internal
Elzbieta Dembowska, Aleksandra Jaron, Joanna Raslawska-Socha, Ewa Gabrysz-Trybek, Joanna Bladowska, Szymon Gacek, Grzegorz Trybek
Summary: This study assessed the extent of gingivitis and periodontitis in hemodialysis patients compared to healthy subjects. The study found that hemodialysis patients had a higher incidence and severity of gingivitis and periodontitis than the control group.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Clinical Neurology
Liling Yang, Zongping Li, Xiaoyu Dai, Lijun Wang, Xiaoyi Wang, Hongyuan Liu
Summary: Nontraumatic subdural hematoma (NSDH) is rare in hemodialysis (HD) patients, but if it occurs, the mortality rate is high. Surgical intervention can reduce the mortality rate of NSDH in HD patients, while atrial fibrillation and the use of oral anticoagulants are associated with an increased risk of mortality in NSDH.
FRONTIERS IN NEUROLOGY
(2023)
Article
Biochemistry & Molecular Biology
Wiktoria Grycuk, Zuzanna Jakubowska, Jolanta Malyszko
Summary: Recent study discovered that proenkephalin A (PENK A) does not reflect renal function and cardiac status in patients with end-stage kidney disease (ESKD). Further research is required to establish the clinical utility of this new biomarker in patients with impaired kidney function.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Immunology
Robson E. Silva, Eliziaria C. Santos, Patricia B. Justino, Margarida P. Santos, Giovane Galdino, Reggiani Goncalves, Romulo D. Novaes
Summary: The relationship between dialysis adequacy and circulating levels of inflammatory mediators was investigated, showing that low Kt/V results and creatinine accumulation may serve as potential indicators of systemic inflammatory stress.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2021)
Article
Medicine, General & Internal
Tomoki Tsurumi, Yuma Tamura, Yuki Nakatani, Tomoki Furuya, Hajime Tamiya, Masato Terashima, Takashi Tomoe, Asuka Ueno, Masahiro Shimoyama, Takanori Yasu
Summary: This study evaluated the effects of neuromuscular electrical stimulation (NMES) on glycemic control in hemodialysis patients. The results showed that both single and long-term application of NMES could lower blood glucose levels and reduce glycemic fluctuations.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Multidisciplinary Sciences
Risako Mikami, Koji Mizutani, Tomohito Gohda, Yusuke Matsuyama, Hiromichi Gotoh, Keita Nakagawa, Shu Takemura, Norio Aoyama, Takanori Matsuura, Daisuke Kido, Kohei Takeda, Natsumi Saito, Yuichi Izumi, Takanori Iwata
Summary: This study investigated the association between oral health status and MIA syndrome in hemodialysis patients. The results showed that severe periodontitis was significantly associated with MIA syndrome, particularly with inflammation and malnutrition, while occlusal support was not associated with MIA syndrome.
SCIENTIFIC REPORTS
(2023)
Article
Infectious Diseases
Jose Molto, Fredzzia Graterol, Adrian Curran, Natalia Ramos, Arkaitz Imaz, Diego Sandoval, Francisco Perez, Lucia Bailon, Saye Khoo, Laura Else, Roger Paredes
Summary: This study evaluated the effect of haemodialysis on doravirine concentrations in people living with HIV (PLWH) undergoing routine haemodialysis. The results showed that despite moderate removal of doravirine by haemodialysis, trough doravirine concentrations in plasma after the haemodialysis sessions remained in excess of the protein-binding-adjusted EC50 (5 ng/mL). Therefore, doravirine dosage adjustments are unnecessary in PLWH undergoing intermittent haemodialysis.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2022)
Article
Environmental Sciences
Hsiu-Lan Li, Pei-Hui Tai, Yi-Ting Hwang, Shih-Wei Lin, Li-Ching Lan
Summary: This study investigated whether the cause of hospital admission changed for patients with end-stage kidney disease (ESKD) before and after receiving hemodialysis. The results revealed that hypertension was the most common comorbidity, pneumonia was more prevalent in older patients, and changes in the ICD-9-CM codes were significantly correlated with age.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Health Care Sciences & Services
Chia-Chen Hsieh, Ming-Jen Chan, Yi-Jiun Su, Jen-Fen Fu, I-Kuan Wang, Chao-Yu Chen, Cheng-Hao Weng, Wen-Hung Huang, Ching-Wei Hsu, Tzung-Hai Yen
Summary: This study found that bone marrow pathology is more severe in patients with ESKD, with lower percentage of blasts and higher incidence of hypocellular bone marrow. ESKD status and megakaryocyte count within bone marrow were significant predictors for bone marrow hypocellularity.
Article
Health Care Sciences & Services
Montira Assanatham, Oraluck Pattanaprateep, Anan Chuasuwan, Kriengsak Vareesangthip, Ouppatham Supasyndh, Adisorn Lumpaopong, Paweena Susantitaphong, Chutatip Limkunakul, Wanchana Ponthongmak, Kamolpat Chaiyakittisopon, Ammarin Thakkinstian, Atiporn Ingsathit
Summary: Using updated real-practice data, the study evaluated the cost-utility of the Peritoneal Dialysis (PD)-First policy compared to hemodialysis (HD) in Thai patients with End-stage Kidney Disease (ESKD) under a universal health coverage scheme. The PD-first policy was found to be more cost-effective than the HD-first policy at the current willingness to pay. However, HD resulted in more quality-adjusted life years than PD. This study provides valuable information for clinicians and policymakers in making decisions regarding dialysis modality selection and kidney replacement therapy reimbursement policies for ESKD patients.
BMC HEALTH SERVICES RESEARCH
(2022)
Article
Multidisciplinary Sciences
Ryoichi Maenosono, Tatsuo Fukushima, Daisuke Kobayashi, Tomohisa Matsunaga, Yusuke Yano, Shunri Taniguchi, Yuya Fujiwara, Kazumasa Komura, Hirofumi Uehara, Maki Kagitani, Hajime Hirano, Teruo Inamoto, Hayahito Nomi, Haruhito Azuma
Summary: Patients with ESRD are at risk of malnutrition and high mortality. The study found an association between unplanned hemodialysis and low GNRI scores with mortality risk.
SCIENTIFIC REPORTS
(2022)
Article
Medicine, General & Internal
Elzbieta Dembowska, Aleksandra Jaron, Ewa Gabrysz-Trybek, Joanna Bladowska, Szymon Gacek, Grzegorz Trybek
Summary: Patients with end-stage renal disease undergoing hemodialysis experience lower quality of life, especially in the physical sphere, compared to healthy subjects. Comprehensive psychological care is indicated for hemodialysis patients due to their poor psychosocial status.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Urology & Nephrology
Masoume Rambod, Nilofar Pasyar, Ali Mohammad Parviniannasab
Summary: This qualitative study aimed to describe hope and identify challenges, strategies, and outcomes of hope in Iranian ESRD patients undergoing hemodialysis. The findings revealed that patients described hope as a positive feeling of expectation and desire for a special thing to happen. They faced threats and opportunities to achieve hope, leading to the need for positive coping strategies and ultimately resulting in growth and excellence.
Article
Health Care Sciences & Services
Jennifer E. Flythe, Adeline Dorough, Julia H. Narendra, Rebecca L. Wingard, Lorien S. Dalrymple, Darren A. DeWalt
QUALITY OF LIFE RESEARCH
(2019)
Article
Urology & Nephrology
Scott Sibbel, Adam G. Walker, Carey Colson, Francesca Tentori, Steven M. Brunelli, Jennifer Flythe
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2019)
Editorial Material
Urology & Nephrology
Jennifer E. Flythe, Thomas H. Hostetter
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2019)
Editorial Material
Medicine, General & Internal
Jennifer E. Flythe
ANNALS OF INTERNAL MEDICINE
(2019)
Article
Urology & Nephrology
Magdalene M. Assimon, M. Alan Brookhart, Jennifer E. Flythe
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2019)
Review
Urology & Nephrology
Jennifer E. Flythe, Nisha Bansal
SEMINARS IN DIALYSIS
(2019)
Article
Urology & Nephrology
Dhruti P. Chen, Jennifer E. Flythe
HEMODIALYSIS INTERNATIONAL
(2020)
Article
Urology & Nephrology
Magdalene M. Assimon, Patrick H. Pun, Lily Wang, Sana M. Al-Khatib, M. Alan Brookhart, David J. Weber, Wolfgang C. Winkelmayer, Jennifer E. Flythe
Summary: This study conducted two cohort studies using the United States Renal Data System to compare the cardiac safety of azithromycin with amoxicillin-based antibiotics and levofloxacin in the hemodialysis population. The results showed that azithromycin treatment was associated with a higher risk of sudden cardiac death compared to amoxicillin-based antibiotics, but a lower risk compared to levofloxacin.
KIDNEY INTERNATIONAL
(2022)
Article
Urology & Nephrology
Yuzhi Xi, David B. Richardson, Abhijit V. Kshirsagar, Jennifer E. Flythe, Eric A. Whitsel, Timothy J. Wade, Ana G. Rappold
Summary: This study aimed to investigate the association between short-term PM2.5 exposure and serum biomarkers. The results from a retrospective study showed that an increase in same-day PM2.5 exposure was associated with lower serum hemoglobin and albumin among patients receiving in-center hemodialysis.
Article
Urology & Nephrology
Rebekah P. P. Nash, Marci M. Loiselle, Jessica L. L. Stahl, Jamie L. Conklin, Terra L. Rose, Alissa Hutto, Donna M. Evon, Jennifer E. Flythe, Eileen J. Burker
Summary: PTG, resilience, and benefit finding seem to reduce the risk of PTSD, promote well-being, and reduce the risk of graft failure in KT recipients.
Article
Urology & Nephrology
Adeline Dorough, Julia H. Narendra, Caroline Wilkie, Akhil Hegde, Kawan Swain, Emily H. Chang, Terence Oliver, Jennifer E. Flythe
Summary: By collaborating with key stakeholders, the research team developed mixed media vascular access education materials that were well-received by patients and providers. Preliminary findings indicate that the materials are promising in improving patients' understanding of vascular access.
Article
Urology & Nephrology
Jennifer E. Flythe, Julia H. Narendra, Christina Yule, Surya Manivannan, Shannon Murphy, Shoou-Yih D. Lee, Tara S. Strigo, Sarah Peskoe, Jane F. Pendergast, L. Ebony Boulware, Jamie A. Green
Summary: This study implemented a quality improvement program to enhance pre-HD vascular access care, resulting in improved patient knowledge and self-efficacy. The findings suggest that interventions targeting patient and health system barriers can effectively improve patient engagement in vascular access care.
Article
Medicine, Research & Experimental
Matthew J. Tugman, Julia H. Narendra, Quefeng Li, Yueting Wang, Alan L. Hinderliter, Steven M. Brunelli, Jennifer E. Flythe
CONTEMPORARY CLINICAL TRIALS COMMUNICATIONS
(2019)
Letter
Urology & Nephrology
Magdalene M. Assimon, Lily Wang, Jennifer E. Flythe
KIDNEY INTERNATIONAL REPORTS
(2019)
Article
Urology & Nephrology
Jennifer E. Flythe, Derek Forfang, Nieltje Gedney, David M. White, Caroline Wilkie, Kerri L. Cavanaugh, Raymond C. Harris, Mark Unruh, Grace Squillaci, Melissa West, Carol Mansfield, Cindy S. Soloe, Katherine Treiman, Dallas Wood, Frank P. Hurst, Carolyn Y. Neuland, Anindita Saha, Murray Sheldon, Michelle E. Tarver
Summary: This study aimed to capture patients' preferences for wearable dialysis devices and in-center hemodialysis through interviews and surveys. A 54-item web-based survey was developed to estimate the maximal acceptable risk for the described wearable device and willingness to wait for wearable devices with lower risk.