Genital inflammation undermines the effectiveness of tenofovir gel in preventing HIV acquisition in women

Genital—Systemic Chemokine Gradients and the Risk of HIV Acquisition in Women

(2017) Lenine J. P. Liebenberg et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Distinct Effects of the Cervicovaginal Microbiota and Herpes Simplex Type 2 Infection on Female Genital Tract Immunology

(2017) B. Shannon et al.   JOURNAL OF INFECTIOUS DISEASES

Vaginal bacteria modify HIV tenofovir microbicide efficacy in African women

(2017) Nichole R. Klatt et al.   SCIENCE

Efficacy of oral pre-exposure prophylaxis (PrEP) for HIV among women with abnormal vaginal microbiota: a post-hoc analysis of the randomised, placebo-controlled Partners PrEP Study

(2017) Renee Heffron et al.   Lancet HIV

Vaginal dysbiosis and pre-exposure prophylaxis efficacy

(2017) Janneke van de Wijgert et al.   Lancet HIV

Intracellular Tenofovir and Emtricitabine Anabolites in Genital, Rectal, and Blood Compartments from First Dose to Steady State

(2016) Sharon M. Seifert et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Cervicovaginal Inflammation Facilitates Acquisition of Less Infectious HIV Variants

(2016) Philippe Selhorst et al.   CLINICAL INFECTIOUS DISEASES

A Translational Pharmacology Approach to Predicting Outcomes of Preexposure Prophylaxis Against HIV in Men and Women Using Tenofovir Disoproxil Fumarate With or Without Emtricitabine

(2016) Mackenzie L. Cottrell et al.   JOURNAL OF INFECTIOUS DISEASES

Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label randomised trial

(2016) Sheena McCormack et al.   LANCET

Use of a Vaginal Ring Containing Dapivirine for HIV-1 Prevention in Women

(2016) Jared M. Baeten et al.   NEW ENGLAND JOURNAL OF MEDICINE

Factors Driving the HIV Epidemic in Southern Africa

(2016) Lyle R. McKinnon et al.   Current HIV/AIDS Reports

Genital Inflammation and the Risk of HIV Acquisition in Women

(2015) Lindi Masson et al.   CLINICAL INFECTIOUS DISEASES

Cervicovaginal Bacteria Are a Major Modulator of Host Inflammatory Responses in the Female Genital Tract

(2015) Melis N. Anahtar et al.   IMMUNITY

Genital Tenofovir Concentrations Correlate With Protection Against HIV Infection in the CAPRISA 004 Trial

(2015) Angela D. M. Kashuba et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Increased levels of inflammatory cytokines in the female reproductive tract are associated with altered expression of proteases, mucosal barrier proteins and an influx of HIV-susceptible target cells

(2015) Kelly B Arnold et al.   Mucosal Immunology

Tenofovir-Based Preexposure Prophylaxis for HIV Infection among African Women

(2015) Jeanne M. Marrazzo et al.   NEW ENGLAND JOURNAL OF MEDICINE

On-Demand Preexposure Prophylaxis in Men at High Risk for HIV-1 Infection

(2015) Jean-Michel Molina et al.   NEW ENGLAND JOURNAL OF MEDICINE

Estimating per-act HIV transmission risk

(2014) Pragna Patel et al.   AIDS

HIV pre-exposure prophylaxis in men who have sex with men and transgender women: a secondary analysis of a phase 3 randomised controlled efficacy trial

(2014) Susan P Buchbinder et al.   LANCET INFECTIOUS DISEASES

Defining genital tract cytokine signatures of sexually transmitted infections and bacterial vaginosis in women at high risk of HIV infection: a cross-sectional study

(2014) Lindi Masson et al.   SEXUALLY TRANSMITTED INFECTIONS

The Rise and Fall of HIV in High-Prevalence Countries: A Challenge for Mathematical Modeling

(2014) Nico J. D. Nagelkerke et al.   PLoS Computational Biology

Efficacy of preexposure prophylaxis for HIV-1 prevention among high-risk heterosexuals

(2013) Pamela M. Murnane et al.   AIDS

HIV pre-exposure prophylaxis in injecting drug users

(2013) Salim S Abdool Karim   LANCET

Concentrated HIV subepidemics in generalized epidemic settings

(2013) Frank Tanser et al.   Current Opinion in HIV and AIDS

Use of Antiretrovirals for HIV Prevention: What Do We Know and What Don’t We Know?

(2013) Jared M. Baeten et al.   Current HIV/AIDS Reports

Antiretroviral Preexposure Prophylaxis for Heterosexual HIV Transmission in Botswana

(2012) Michael C. Thigpen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Antiretroviral Prophylaxis for HIV Prevention in Heterosexual Men and Women

(2012) Jared M. Baeten et al.   NEW ENGLAND JOURNAL OF MEDICINE

Preexposure Prophylaxis for HIV Infection among African Women

(2012) Lut Van Damme et al.   NEW ENGLAND JOURNAL OF MEDICINE

Quality and quantity

(2012) Lyle R. McKinnon et al.   Current Opinion in HIV and AIDS

Natural Substrate Concentrations Can Modulate the Prophylactic Efficacy of Nucleotide HIV Reverse Transcriptase Inhibitors

(2011) J. G. Garcia-Lerma et al.   JOURNAL OF VIROLOGY

Recruitment of high risk women for HIV prevention trials: baseline HIV prevalence and sexual behavior in the CAPRISA 004 tenofovir gel trial

(2011) Quarraisha Abdool Karim et al.   Trials

Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men

(2010) Robert M. Grant et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women

(2010) Q. Abdool Karim et al.   SCIENCE

Heterosexual risk of HIV-1 infection per sexual act: systematic review and meta-analysis of observational studies

(2009) Marie-Claude Boily et al.   LANCET INFECTIOUS DISEASES

Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand

(2009) Supachai Rerks-Ngarm et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rethinking the heterosexual infectivity of HIV-1: a systematic review and meta-analysis

(2008) Kimberly A Powers et al.   LANCET INFECTIOUS DISEASES