Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy

Glycolytic-to-oxidative fiber-type switch and mTOR signaling activation are early-onset features of SBMA muscle modified by high-fat diet

(2016) Anna Rocchi et al.   ACTA NEUROPATHOLOGICA

A small-molecule Nrf1 and Nrf2 activator mitigates polyglutamine toxicity in spinal and bulbar muscular atrophy

(2016) Laura C. Bott et al.   HUMAN MOLECULAR GENETICS

Identification of a Potent Antiandrogen that Targets the BF3 Site of the Androgen Receptor and Inhibits Enzalutamide-Resistant Prostate Cancer

(2014) Ravi S.N. Munuganti et al.   CHEMISTRY & BIOLOGY

Coregulator Control of Androgen Receptor Action by a Novel Nuclear Receptor-binding Motif

(2014) Katja Jehle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discovery of 1H-Indole-2-carboxamides as Novel Inhibitors of the Androgen Receptor Binding Function 3 (BF3)

(2014) Fuqiang Ban et al.   JOURNAL OF MEDICINAL CHEMISTRY

Correlation of clinical and molecular features in spinal bulbar muscular atrophy

(2014) P. Fratta et al.   NEUROLOGY

Association between CAG repeat polymorphisms and the risk of prostate cancer: A meta-analysis by race, study design and the number of (CAG)n repeat polymorphisms

(2013) JUN-HYUN SUN et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Targeting the Binding Function 3 (BF3) Site of the Androgen Receptor Through Virtual Screening. 2. Development of 2-((2-phenoxyethyl) thio)-1H-benzimidazole Derivatives

(2013) Ravi Shashi Nayana Munuganti et al.   JOURNAL OF MEDICINAL CHEMISTRY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Inhibitors of Androgen Receptor Activation Function-2 (AF2) Site Identified through Virtual Screening

(2011) Peter Axerio-Cilies et al.   JOURNAL OF MEDICINAL CHEMISTRY

Targeting the Binding Function 3 (BF3) Site of the Human Androgen Receptor through Virtual Screening.

(2011) Nathan A. Lack et al.   JOURNAL OF MEDICINAL CHEMISTRY

Corepressor effect on androgen receptor activity varies with the length of the CAG encoded polyglutamine repeat and is dependent on receptor/corepressor ratio in prostate cancer cells

(2011) Grant Buchanan et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Perspectives of Kennedy's disease

(2010) J. Finsterer   JOURNAL OF THE NEUROLOGICAL SCIENCES

Efficacy and safety of leuprorelin in patients with spinal and bulbar muscular atrophy (JASMITT study): a multicentre, randomised, double-blind, placebo-controlled trial

(2010) Masahisa Katsuno et al.   LANCET NEUROLOGY

Suppression of the androgen receptor function by quercetin through protein–protein interactions of Sp1, c-Jun, and the androgen receptor in human prostate cancer cells

(2010) Huiqing Yuan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Native Functions of the Androgen Receptor Are Essential to Pathogenesis in a Drosophila Model of Spinobulbar Muscular Atrophy

(2010) Natalia B. Nedelsky et al.   NEURON

Phase 2 trial of leuprorelin in patients with spinal and bulbar muscular atrophy

(2009) Haruhiko Banno et al.   ANNALS OF NEUROLOGY

Spinal cord blood flow measurement by arterial spin labeling

(2008) Guillaume Duhamel et al.   MAGNETIC RESONANCE IN MEDICINE

Structural basis for nuclear receptor corepressor recruitment by antagonist-liganded androgen receptor

(2008) Myles C. Hodgson et al.   MOLECULAR CANCER THERAPEUTICS

Natural history of spinal-bulbar muscular atrophy

(2008) N. Chahin et al.   NEUROLOGY

Physiologically based Pharmacokinetic Modeling of Chloroethane Disposition in Mice, Rats, and Women

(2008) Michael L. Gargas et al.   TOXICOLOGICAL SCIENCES

Androgen receptor variants and prostate cancer in humanized AR mice

(2007) Diane M. Robins et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Spinal and bulbar muscular atrophy: Skeletal muscle pathology in male patients and heterozygous females

(2007) Gianni Sorarù et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES