Checkpoint inhibition: NK cells enter the scene

Blockade of the checkpoint receptor TIGIT prevents NK cell exhaustion and elicits potent anti-tumor immunity

(2018) Qing Zhang et al.   NATURE IMMUNOLOGY

Natural killer cell immunotherapies against cancer: checkpoint inhibitors and more

(2017) Laura Chiossone et al.   SEMINARS IN IMMUNOLOGY

Molecular Pathways: Targeting CD96 and TIGIT for Cancer Immunotherapy

(2016) S. J. Blake et al.   CLINICAL CANCER RESEARCH

The urgent need to recover MHC class I in cancers for effective immunotherapy

(2016) Federico Garrido et al.   CURRENT OPINION IN IMMUNOLOGY

Suppression of Metastases Using a New Lymphocyte Checkpoint Target for Cancer Immunotherapy

(2016) S. J. Blake et al.   Cancer Discovery

Features of Memory-Like and PD-1+ Human NK Cell Subsets

(2016) Mariella Della Chiesa et al.   Frontiers in Immunology

The Immunoreceptor TIGIT Regulates Antitumor and Antiviral CD8 + T Cell Effector Function

(2014) Robert J. Johnston et al.   CANCER CELL

CTLA-4 Is Expressed by Activated Mouse NK Cells and Inhibits NK Cell IFN-  Production in Response to Mature Dendritic Cells

(2014) A. Stojanovic et al.   JOURNAL OF IMMUNOLOGY

The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity

(2009) N. Stanietsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells

(2008) Xin Yu et al.   NATURE IMMUNOLOGY