Cross-fibrillation of insulin and amyloid β on chiral surfaces: Chirality affects aggregation kinetics and cytotoxicity

Insulin Levels are Decreased in the Cerebrospinal Fluid of Women with Prodomal Alzheimer's Disease

(2017) Francisco J. Gil-Bea et al.   JOURNAL OF ALZHEIMERS DISEASE

Reciprocal Molecular Interactions between the Aβ Peptide Linked to Alzheimer’s Disease and Insulin Linked to Diabetes Mellitus Type II

(2016) Jinghui Luo et al.   ACS Chemical Neuroscience

Ionizing radiation-engineered nanogels as insulin nanocarriers for the development of a new strategy for the treatment of Alzheimer's disease

(2016) Pasquale Picone et al.   BIOMATERIALS

Surface Roughness Modulates Diffusion and Fibrillation of Amyloid-β Peptide

(2016) Khurram Shezad et al.   LANGMUIR

Polyoxometalate-based nanozyme: Design of a multifunctional enzyme for multi-faceted treatment of Alzheimer’s disease

(2016) Nan Gao et al.   Nano Research

Protein/Peptide Aggregation and Amyloidosis on Biointerfaces

(2016) Qi Lu et al.   Materials

Contact between the β1 and β2 Segments of α-Synuclein that Inhibits Amyloid Formation

(2015) Hamed Shaykhalishahi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Unusual Cyclodextrin Derivatives as a New Avenue to Modulate Self- and Metal-Induced Aβ Aggregation

(2015) Valentina Oliveri et al.   CHEMISTRY-A EUROPEAN JOURNAL

How does brain insulin resistance develop in Alzheimer's disease?

(2014) Fernanda G. De Felice et al.   Alzheimers & Dementia

Chirality-Assisted Ring-Like Aggregation of Aβ(1-40) at Liquid-Solid Interfaces: A Stereoselective Two-Step Assembly Process

(2014) Guanbin Gao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Supramolecular Inhibition of Amyloid Fibrillation by Cucurbit[7]uril

(2014) Hong Hee Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Differential regulation of osteogenic differentiation of stem cells on surface roughness gradients

(2014) Ana B. Faia-Torres et al.   BIOMATERIALS

Differences between amyloid-β aggregation in solution and on the membrane: insights into elucidation of the mechanistic details of Alzheimer's disease

(2014) Samuel A. Kotler et al.   CHEMICAL SOCIETY REVIEWS

Chiral Effect at Protein/Graphene Interface: A Bioinspired Perspective To Understand Amyloid Formation

(2014) Guangyan Qing et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral Metallohelical Complexes Enantioselectively Target Amyloid β for Treating Alzheimer’s Disease

(2014) Meng Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Presence of an Air–Water Interface Affects Formation and Elongation of α-Synuclein Fibrils

(2014) Silvia Campioni et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The amyloid state and its association with protein misfolding diseases

(2014) Tuomas P. J. Knowles et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Opposing enantiomers of tartaric acid anchored on a surface generate different insulin assemblies and hence contrasting cellular responses

(2014) Weili Wei et al.   Chemical Science

The Catalytically Active Copper-Amyloid-Beta State: Coordination Site Responsible for Reactive Oxygen Species Production

(2013) Laure-Estelle Cassagnes et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Distinct α-Synuclein Strains Differentially Promote Tau Inclusions in Neurons

(2013) Jing L. Guo et al.   CELL

In Vitro and Mechanistic Studies of an Antiamyloidogenic Self-Assembled Cyclic d,l-α-Peptide Architecture

(2013) Michal Richman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Design and Synthesis of Curcumin Analogues for in Vivo Fluorescence Imaging and Inhibiting Copper-Induced Cross-Linking of Amyloid Beta Species in Alzheimer’s Disease

(2013) Xueli Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Amyloid-β nanotubes are associated with prion protein-dependent synaptotoxicity

(2013) Andrew J. Nicoll et al.   Nature Communications

The Amyloid Beta Peptide: A Chemist’s Perspective. Role in Alzheimer’s and Fibrillization

(2012) I. W. Hamley   CHEMICAL REVIEWS

Insulin Promotes Neuronal Survival via the Alternatively Spliced Protein Kinase CδII Isoform

(2012) André Apostolatos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Mobile Precursor Determines Amyloid-β Peptide Fibril Formation at Interfaces

(2012) Lei Shen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Insulin resistance and AD—extending the translational path

(2012) Suzanne Craft   Nature Reviews Neurology

The many faces of insulin-like peptide signalling in the brain

(2012) Ana M. Fernandez et al.   NATURE REVIEWS NEUROSCIENCE

Influence of Hydrophobicity on the Surface-Catalyzed Assembly of the Islet Amyloid Polypeptide

(2011) Adrian Keller et al.   ACS Nano

Cross-Amyloid Interaction of Aβ and IAPP at Lipid Membranes

(2011) Janine Seeliger et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Intranasal Insulin Therapy for Alzheimer Disease and Amnestic Mild Cognitive Impairment

(2011) Suzanne Craft   ARCHIVES OF NEUROLOGY

Interface influence

(2010) Ian W. Hamley   Nature Chemistry

Linking type 2 diabetes and Alzheimer's disease

(2010) W. Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bovine Insulin Filaments Induced by Reducing Disulfide Bonds Show a Different Morphology, Secondary Structure, and Cell Toxicity from Intact Insulin Amyloid Fibrils

(2009) Tamotsu Zako et al.   BIOPHYSICAL JOURNAL

Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of Aβ oligomers

(2009) Fernanda G. De Felice et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of Amyloid β Protein Fibrillation by Polymeric Nanoparticles

(2008) Celia Cabaleiro-Lago et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of A  toxicity

(2008) J. N. Buxbaum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insulin rescues amyloid β-induced impairment of hippocampal long-term potentiation

(2007) Cheng-Che Lee et al.   NEUROBIOLOGY OF AGING