Journal
MOLECULES
Volume 23, Issue 5, Pages -Publisher
MDPI
DOI: 10.3390/molecules23051119
Keywords
lectin; teleost; mucosal; innate immunology; antibacterial; phagocytosis; agglutination
Funding
- Norwegian Seafood Research Fund-FHF grant [901136]
Ask authors/readers for more resources
Mucosal surfaces are of key importance in protecting animals against external threats including pathogens. In the mucosal surfaces, host molecules interact with non-self to prevent infection and disease. Interestingly, both inhibition and stimulation of uptake hinder infection. In this review, the current knowledgebase on teleost mucosal lectins' ability to interact with non-self is summarised with a focus on agglutination, growth inhibition, opsonisation, cell adhesion, and direct killing activities. Further research on lectins is essential, both to understand the immune system of fishes, since they rely more on the innate immune system than mammals, and also to explore these molecules' antibiotic and antiparasitic activities against veterinary and human pathogens.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available