Novel Structural Insight into Inhibitors of Heme Oxygenase-1 (HO-1) by New Imidazole-Based Compounds: Biochemical and In Vitro Anticancer Activity Evaluation

Nrf2 as regulator of innate immunity: A molecular Swiss army knife!

(2018) Maurizio Battino et al.   BIOTECHNOLOGY ADVANCES

Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions

(2018) Valeria Pittala et al.   CURRENT MEDICINAL CHEMISTRY

Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors

(2018) Loredana Salerno et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Hyphenated 3D-QSAR statistical model-scaffold hopping analysis for the identification of potentially potent and selective sigma-2 receptor ligands

(2017) Giuseppe Floresta et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Recent advances in drug discovery of phototherapeutic non-porphyrinic anticancer agents

(2017) Maria Dichiara et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

S2RSLDB: a comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands

(2017) Giovanni Nastasi et al.   Journal of Cheminformatics

A Focus on Heme Oxygenase-1 (HO-1) Inhibitors

(2016) V. Pittalà et al.   CURRENT MEDICINAL CHEMISTRY

Novel imidazole derivatives as heme oxygenase-1 (HO-1) and heme oxygenase-2 (HO-2) inhibitors and their cytotoxic activity in human-derived cancer cell lines

(2015) Loredana Salerno et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Heme oxygenase-1 in pregnancy and cancer: similarities in cellular invasion, cytoprotection, angiogenesis, and immunomodulation

(2015) Hui Zhao et al.   Frontiers in Pharmacology

Polymeric micelles as drug carriers: their lights and shadows

(2014) Masayuki Yokoyama   JOURNAL OF DRUG TARGETING

Antitumor properties of substituted (αE)-α-(1H-indol-3-ylmethylene)benzeneacetic acids or amides

(2013) Giuseppe Forte et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties

(2013) Loredana Salerno et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Expression of nerve growth factor and heme oxygenase-1 predict poor survival of breast carcinoma patients

(2013) Sang Jae Noh et al.   BMC CANCER

Oncogenic potential of Nrf2 and its principal target protein heme oxygenase-1

(2013) Hye-Kyung Na et al.   FREE RADICAL BIOLOGY AND MEDICINE

Experimental and in silico characterization of a biologically active inosose

(2013) Venerando Pistarà et al.   STRUCTURAL CHEMISTRY

The induction of heme oxygenase-1 suppresses heat shock protein 90 and the proliferation of human breast cancer cells through its byproduct carbon monoxide

(2013) Wen-Ying Lee et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Evaluation of Imidazole-Based Compounds as Heme Oxygenase-1 Inhibitors

(2012) Valeria Sorrenti et al.   Chemical Biology & Drug Design

Heme Oxygenase Inhibition by α-(1H-Imidazol-1-yl)-ω-phenylalkanes: Effect of Introduction of Heteroatoms in the Alkyl Linker

(2012) Jason Z. Vlahakis et al.   ChemMedChem

Anticancer nanomedicine and tumor vascular permeability; Where is the missing link?

(2012) Sebastien Taurin et al.   JOURNAL OF CONTROLLED RELEASE

Structural insights into human heme oxygenase-1 inhibition by potent and selective azole-based compounds

(2012) M. N. Rahman et al.   Journal of the Royal Society Interface

Could 2,6-bis((E)-2-(furan-2-yl)vinyl)-1-methylpyridinium iodide and analog compounds intercalate DNA? A first principle prediction based on structural and electronic properties

(2012) Cosimo G. Fortuna et al.   Computational and Theoretical Chemistry

Synthesis and molecular modeling of 1H-pyrrolopyrimidine-2,4-dione derivatives as ligands for the α1-adrenoceptors

(2011) Valeria Pittalà et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, Synthesis, Molecular Docking and Crystal Structure Prediction of New Azasugar Analogues of α-Glucosidase Inhibitors

(2011) Venerando Pistarà et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect

(2010) Jun Fang et al.   ADVANCED DRUG DELIVERY REVIEWS

Thieno[3,2-c]pyrazoles: A novel class of Aurora inhibitors with favorable antitumor activity

(2010) Simona Bindi et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Heme Oxygenase Inhibition by 1-Aryl-2-(1H-imidazol-1-yl/1H-1,2,4-triazol-1-yl)ethanones and Their Derivatives

(2010) Gheorghe Roman et al.   ChemMedChem

Gabedit-A graphical user interface for computational chemistry softwares

(2010) Abdul-Rahman Allouche   JOURNAL OF COMPUTATIONAL CHEMISTRY

A Novel Experimental Heme Oxygenase-1-Targeted Therapy for Hormone-Refractory Prostate Cancer

(2009) M. A. Alaoui-Jamali et al.   CANCER RESEARCH

Heme Oxygenase Inhibition by 2-Oxy-substituted 1-Azolyl-4-phenylbutanes: Effect of Variation of the Azole Moiety. X-Ray Crystal Structure of Human Heme Oxygenase-1 in Complex with 4-Phenyl-1-(1H-1,2,4-triazol-1-yl)-2-butanone

(2009) Gheorghe Roman et al.   Chemical Biology & Drug Design

Critical Role of Endogenous Heme Oxygenase 1 as a Tuner of the Invasive Potential of Prostate Cancer Cells

(2009) G. Gueron et al.   MOLECULAR CANCER RESEARCH

Pharmacological and Clinical Aspects of Heme Oxygenase

(2008) N. G. Abraham et al.   PHARMACOLOGICAL REVIEWS