4.6 Article

Electrochemical Aptamer-Based Sensors for Rapid Point-of-Use Monitoring of the Mycotoxin Ochratoxin A Directly in a Food Stream

Journal

MOLECULES
Volume 23, Issue 4, Pages -

Publisher

MDPI
DOI: 10.3390/molecules23040912

Keywords

food taint; E-AB sensor; biosensor; mycotoxin; point-of-care; electrochemical sensor; aptamer

Funding

  1. Institute for Collaborative Bio-technologies from the U.S. Army Research Office [W911NF-09-0001]
  2. National Institutes of Health [R01EB022015]
  3. National Cancer Institute of the National Institute of Health [NRSA F31CA183385]
  4. NATIONAL CANCER INSTITUTE [F31CA183385] Funding Source: NIH RePORTER
  5. NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [R01EB022015] Funding Source: NIH RePORTER

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The ability to measure the concentration of specific small molecules continuously and in real-time in complex sample streams would impact many areas of agriculture, food safety, and food production. Monitoring for mycotoxin taint in real time during food processing, for example, could improve public health. Towards this end, we describe here an inexpensive electrochemical DNA-based sensor that supports real-time monitor of the mycotoxin ochratoxin A in a flowing stream of foodstuffs.

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