Problems in interpreting and using GWAS of conditional phenotypes illustrated by 'alcohol GWAS'

When Will Mendelian Randomization Become Relevant for Clinical Practice and Public Health?

(2017) George Davey Smith et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genetic Association of Waist-to-Hip Ratio With Cardiometabolic Traits, Type 2 Diabetes, and Coronary Heart Disease

(2017) Connor A. Emdin et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117)

(2017) T-K Clarke et al.   MOLECULAR PSYCHIATRY

Mendelian randomization in cardiometabolic disease: challenges in evaluating causality

(2017) Michael V. Holmes et al.   Nature Reviews Cardiology

Adjusting for Heritable Covariates Can Bias Effect Estimates in Genome-Wide Association Studies

(2015) Hugues Aschard et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

(2014) M. V. Holmes et al.   BMJ-British Medical Journal