Rapid proteomic analysis for solid tumors reveals LSD1 as a drug target in an end-stage cancer patient

Cancer Genome Interpreter annotates the biological and clinical relevance of tumor alterations

(2018) David Tamborero et al.   Genome Medicine

Tranylcypromine in mind (Part I): Review of pharmacology

(2017) Sven Ulrich et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Region and cell-type resolved quantitative proteomic map of the human heart

(2017) Sophia Doll et al.   Nature Communications

Inhibition of LSD1 epigenetically attenuates oral cancer growth and metastasis

(2017) Saqer F. Alsaqer et al.   Oncotarget

Integrated analysis of genes associated with poor prognosis of patients with colorectal cancer liver metastasis

(2017) Zhenyuan Qian et al.   Oncotarget

Pan-cancer EMT-signature identifies RBM47 down-regulation during colorectal cancer progression

(2017) Matjaz Rokavec et al.   Scientific Reports

Irreversible LSD1 Inhibitors: Application of Tranylcypromine and Its Derivatives in Cancer Treatment

(2016) Yi C. Zheng et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Urachal Carcinoma Shares Genomic Alterations with Colorectal Carcinoma and May Respond to Epidermal Growth Factor Inhibition

(2016) Ana Collazo-Lorduy et al.   EUROPEAN UROLOGY

Proteomics reveals the effects of sustained weight loss on the human plasma proteome

(2016) Philipp E Geyer et al.   Molecular Systems Biology

Mass-spectrometric exploration of proteome structure and function

(2016) Ruedi Aebersold et al.   NATURE

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

Clinical, prognostic, and therapeutic aspects of urachal carcinoma—A comprehensive review with meta-analysis of 1,010 cases

(2016) Tibor Szarvas et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status

(2016) F. Coscia et al.   Nature Communications

Associations of THBS2 and THBS4 polymorphisms to gastric cancer in a Southeast Chinese population

(2016) Xiandong Lin et al.   Cancer Genetics

Whole exome sequencing of urachal adenocarcinoma reveals recurrent NF1 mutations

(2016) Harshabad Singh et al.   Oncotarget

Plasma Proteome Profiling to Assess Human Health and Disease

(2016) Philipp E. Geyer et al.   Cell Systems

THBS2 is a Potential Prognostic Biomarker in Colorectal Cancer

(2016) Xue Wang et al.   Scientific Reports

FOLFOX4 plus cetuximab treatment and RAS mutations in colorectal cancer

(2015) C. Bokemeyer et al.   EUROPEAN JOURNAL OF CANCER

Personalized medicine: Time for one-person trials

(2015) Nicholas J. Schork   NATURE

Preclinical activity of combined HDAC and KDM1A inhibition in glioblastoma

(2015) Melissa M. Singh et al.   NEURO-ONCOLOGY

Rapid and Deep Proteomes by Faster Sequencing on a Benchtop Quadrupole Ultra-High-Field Orbitrap Mass Spectrometer

(2014) Christian D. Kelstrup et al.   JOURNAL OF PROTEOME RESEARCH

The Q Exactive HF, a Benchtop Mass Spectrometer with a Pre-filter, High-performance Quadrupole and an Ultra-high-field Orbitrap Analyzer

(2014) Richard Alexander Scheltema et al.   MOLECULAR & CELLULAR PROTEOMICS

Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ

(2014) Jürgen Cox et al.   MOLECULAR & CELLULAR PROTEOMICS

Minimal, encapsulated proteomic-sample processing applied to copy-number estimation in eukaryotic cells

(2014) Nils A Kulak et al.   NATURE METHODS

Periostin is a novel therapeutic target that predicts and regulates glioma malignancy

(2014) Andrei M. Mikheev et al.   NEURO-ONCOLOGY

Periostin suppression induces decorin secretion leading to reduced breast cancer cell motility and invasion

(2014) Toshiyuki Ishiba et al.   Scientific Reports

High-stage urachal adenocarcinoma can be associated with microsatellite instability and KRAS mutations

(2013) S. Joseph Sirintrapun et al.   HUMAN PATHOLOGY

Expression and Prognostic Significance of a Comprehensive Epithelial-Mesenchymal Transition Gene Set in Renal Cell Carcinoma

(2013) Dong Chen et al.   JOURNAL OF UROLOGY

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

(2013) Kristian Cibulskis et al.   NATURE BIOTECHNOLOGY

The Cancer Genome Atlas Pan-Cancer analysis project

(2013) John N Weinstein et al.   NATURE GENETICS

Panitumumab–FOLFOX4 Treatment and RAS Mutations in Colorectal Cancer

(2013) Jean-Yves Douillard et al.   NEW ENGLAND JOURNAL OF MEDICINE

Proteomic workflow for analysis of archival formalin-fixed and paraffin-embedded clinical samples to a depth of 10 000 proteins

(2012) Jacek R. Wiśniewski et al.   Proteomics Clinical Applications

High Recovery FASP Applied to the Proteomic Analysis of Microdissected Formalin Fixed Paraffin Embedded Cancer Tissues Retrieves Known Colon Cancer Markers

(2011) Jacek R. Wiśniewski et al.   JOURNAL OF PROTEOME RESEARCH

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

Advances Pertaining to the Pharmacology and Interactions of Irreversible Nonselective Monoamine Oxidase Inhibitors

(2010) Peter Kenneth Gillman   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases LSD1 and LSD2

(2010) Claudia Binda et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

A Mediator of Rho-dependent Invasion Moonlights as a Methionine Salvage Enzyme

(2009) Yukihito Kabuyama et al.   MOLECULAR & CELLULAR PROTEOMICS

The cancer genome

(2009) Michael R. Stratton et al.   NATURE

Thrombospondins function as regulators of angiogenesis

(2009) Paul Bornstein   Journal of Cell Communication and Signaling

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY