Dehydroepiandrosterone Induces Temozolomide Resistance Through Modulating Phosphorylation and Acetylation of Sp1 in Glioblastoma

CBTRUS Statistical Report: Primary brain and other central nervous system tumors diagnosed in the United States in 2010–2014

(2017) Quinn T Ostrom et al.   NEURO-ONCOLOGY

Upregulation of CYP17A1 by Sp1-mediated DNA demethylation confers temozolomide resistance through DHEA-mediated protection in glioma

(2017) J-Y Chuang et al.   Oncogenesis

Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O 6 -methylguanine-DNA methyltransferase

(2017) Kwang-Yu Chang et al.   Redox Biology

DNA Repair Capacity in Multiple Pathways Predicts Chemoresistance in Glioblastoma Multiforme

(2016) Zachary D. Nagel et al.   CANCER RESEARCH

Augmented HR Repair Mediates Acquired Temozolomide Resistance in Glioblastoma

(2016) C. R. Gil del Alcazar et al.   MOLECULAR CANCER RESEARCH

New insights into acquired temozolomide resistance in glioblastoma?

(2015) Caroline Happold et al.   BRAIN

Phosphorylated Sp1 is the regulator of DNA-PKcs and DNA ligase IV transcription of daunorubicin-resistant leukemia cell lines

(2014) Yayoi Nishida et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

LYN-activating mutations mediate antiestrogen resistance in estrogen receptor–positive breast cancer

(2014) Luis J. Schwarz et al.   JOURNAL OF CLINICAL INVESTIGATION

The Role of Gene Body Cytosine Modifications in MGMT Expression and Sensitivity to Temozolomide

(2014) E. L. Moen et al.   MOLECULAR CANCER THERAPEUTICS

Glioblastoma and Other Malignant Gliomas

(2013) Antonio Omuro   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Stimulation of the Sigma-1 Receptor by DHEA Enhances Synaptic Efficacy and Neurogenesis in the Hippocampal Dentate Gyrus of Olfactory Bulbectomized Mice

(2013) Shigeki Moriguchi et al.   PLoS One

Sp1 Facilitates DNA Double-Strand Break Repair through a Nontranscriptional Mechanism

(2012) K. Beishline et al.   MOLECULAR AND CELLULAR BIOLOGY

Sp1 phosphorylation by cyclin-dependent kinase 1/cyclin B1 represses its DNA-binding activity during mitosis in cancer cells

(2012) J-Y Chuang et al.   ONCOGENE

Overcoming Temozolomide Resistance in Glioblastoma via Dual Inhibition of NAD+ Biosynthesis and Base Excision Repair

(2011) E. M. Goellner et al.   CANCER RESEARCH

Chromosomal Instability Confers Intrinsic Multidrug Resistance

(2011) A. J. X. Lee et al.   CANCER RESEARCH

Blockade of testicular and adrenal androgens in prostate cancer treatment

(2011) Fernand Labrie   Nature Reviews Urology

Temozolomide: Mechanisms of Action, Repair and Resistance

(2011) Jihong Zhang et al.   Current Molecular Pharmacology

MGMT-Independent Temozolomide Resistance in Pediatric Glioblastoma Cells Associated with a PI3-Kinase-Mediated HOX/Stem Cell Gene Signature

(2010) N. Gaspar et al.   CANCER RESEARCH

Sp1 acetylation is associated with loss of DNA binding at promoters associated with cell cycle arrest and cell death in a colon cell line

(2010) Jennifer S Waby et al.   Molecular Cancer

Analysis of DNA Double-strand Break (DSB) Repair in Mammalian Cells

(2010) Andrei Seluanov et al.   Jove-Journal of Visualized Experiments

Neurosteroid dehydroepiandrosterone exerts anti-apoptotic effects by membrane-mediated, integrated genomic and non-genomic pro-survival signaling pathways

(2008) Ioannis Charalampopoulos et al.   JOURNAL OF NEUROCHEMISTRY

Persistent LYN Signaling in Imatinib-Resistant, BCR-ABL–Independent Chronic Myelogenous Leukemia

(2008) Thomas O'Hare et al.   JNCI-Journal of the National Cancer Institute