Preclinical Evaluation of a Novel TSPO PET Ligand 2-(7-Butyl-2-(4-(2-[18F]Fluoroethoxy)phenyl)-5-Methylpyrazolo[1,5-a]Pyrimidin-3-yl)-N,N-Diethylacetamide (18F-VUIIS1018A) to Image Glioma

Evaluation of TSPO PET Ligands [18F]VUIIS1009A and [18F]VUIIS1009B: Tracers for Cancer Imaging

(2016) Dewei Tang et al.   MOLECULAR IMAGING AND BIOLOGY

Preclinical TSPO Ligand PET to Visualize Human Glioma Xenotransplants: A Preliminary Study

(2015) Jason R. Buck et al.   PLoS One

Facile synthesis of SSR180575 and discovery of 7-chloro- N , N ,5-trimethyl-4-oxo-3(6-[ 18 F]fluoropyridin-2-yl)-3,5-dihydro-4 H -pyridazino[4,5- b ]indole-1-acetamide, a potent pyridazinoindole ligand for PET imaging of TSPO in cancer

(2014) Yiu-Yin Cheung et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Preclinical Imaging Evaluation of Novel TSPO-PET Ligand 2-(5,7-Diethyl-2-(4-(2-[18F]fluoroethoxy)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)-N,N-diethylacetamide ([18F]VUIIS1008) in Glioma

(2014) Dewei Tang et al.   MOLECULAR IMAGING AND BIOLOGY

Positron-Emission Tomography Imaging of the TSPO with [18F]FEPPA in a Preclinical Breast Cancer Model

(2013) Neil Vasdev et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Synthesis and Structure–Activity Relationships of 5,6,7-Substituted Pyrazolopyrimidines: Discovery of a Novel TSPO PET Ligand for Cancer Imaging

(2013) Dewei Tang et al.   JOURNAL OF MEDICINAL CHEMISTRY

The translocator protein ligand [18F]DPA-714 images glioma and activated microglia in vivo

(2012) Alexandra Winkeler et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Molecular imaging of microglia/macrophages in the brain

(2012) Sriram Venneti et al.   GLIA

Quantitative Preclinical Imaging of TSPO Expression in Glioma Using N,N-Diethyl-2-(2-(4-(2-18F-Fluoroethoxy)Phenyl)-5,7-Dimethylpyrazolo[1,5-a]Pyrimidin-3-yl)Acetamide

(2012) D. Tang et al.   JOURNAL OF NUCLEAR MEDICINE

Pharmacokinetic Studies of 68Ga-Labeled Bombesin (68Ga-BZH3) and F-18 FDG PET in Patients With Recurrent Gliomas and Comparison to Grading

(2011) Antonia Dimitrakopoulou-Strauss et al.   CLINICAL NUCLEAR MEDICINE

Differential Expression of the 18 kDa Translocator Protein (TSPO) by Neoplastic and Inflammatory Cells in Mouse Tumors of Breast Cancer

(2011) Jinzi Zheng et al.   MOLECULAR PHARMACEUTICS

Quantitative, Preclinical PET of Translocator Protein Expression in Glioma Using 18F-N-Fluoroacetyl-N-(2,5-Dimethoxybenzyl)-2-Phenoxyaniline

(2010) J. R. Buck et al.   JOURNAL OF NUCLEAR MEDICINE

Advanced MRI and PET imaging for assessment of treatment response in patients with gliomas

(2010) Frederic G Dhermain et al.   LANCET NEUROLOGY

Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders

(2010) Rainer Rupprecht et al.   NATURE REVIEWS DRUG DISCOVERY

Microwave-assisted organic synthesis of a high-affinity pyrazolo-pyrimidinyl TSPO ligand

(2010) Dewei Tang et al.   TETRAHEDRON LETTERS

Molecular Imaging of the Translocator Protein (TSPO) in a Pre-Clinical Model of Breast Cancer

(2009) Shelby K. Wyatt et al.   MOLECULAR IMAGING AND BIOLOGY

PET Imaging of the Peripheral Benzodiazepine Receptor: Monitoring Disease Progression and Therapy Response in Neurodegenerative Disorders

(2008) Janine Doorduin et al.   CURRENT PHARMACEUTICAL DESIGN

Nuclear imaging of neuroinflammation: a comprehensive review of [11C]PK11195 challengers

(2008) Fabien Chauveau et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING